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Blood Homocysteine Levels Mediate the Association Between Blood Lead Levels and Cardiovascular Mortality
(
Springer Nature
, 2024 , Article)
Lead is a heavy, toxic metal and its exposure to humans can lead to increased risk of cardiovascular disease development and mortality. Lead exposure has been shown to induce hyperhomocysteinemia (HHCy) which may be a major ...
A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
(
American Society for Biochemistry and Molecular Biology
, 2015 , Article)
Retinal hyperpermeability and subsequent macular edema is a cardinal feature of early diabetic retinopathy (DR). Here, we investigated the role of bioactive lipid metabolites, in particular 12/15-lipoxygenase (LOX)-derived ...
Helicobacter pylori and epithelial mesenchymal transition in human gastric cancers: An update of the literature
(
Elsevier
, 2023 , Article Review)
Gastric cancer, a multifactorial disease, is considered one of the most common malignancies worldwide. In addition to genetic and environmental risk factors, infectious agents, such as Epstein-Barr virus (EBV) and Helicobacter ...
Fructose intake and its association with relative telomere length: an exploratory study among healthy Lebanese adults
(
Frontiers Media
, 2023 , Article)
Introduction: Shorter relative telomere length (RTL) has been associated with increased incidence of morbidity. Although still disputed, available evidence suggests that dietary factors, including sugar-sweetened beverages ...
Seroprevalence of hepatitis E virus (HEV) among male craft and manual workers in Qatar (2020–2021)
(
Elsevier
, 2023 , Article)
BackgroundThe rapid growth of Qatar in the last two decades has attracted a large influx of immigrant craft and manual workers (CMWs) seeking employment in jobs associated with food handling, domestic service, and construction. ...
Laboratory testing efficiency during the COVID pandemic: Findings from the Primary Health Care Corporation laboratories in the State of Qatar
(
Elsevier Ltd
, 2024 , Article)
Background
Little is known about how the COVID-19 pandemic altered laboratory testing efficiency in the State of Qatar. The aim of this study was to assess laboratory testing efficiency with respect to the total number ...
Testosterone treatment and change of categories of the International prostate symptom score (IPSS) in hypogonadal patients: 12 years prospective controlled registry study
(
Taylor and Francis Ltd.
, 2023 , Article)
Functional hypogonadism is a condition characterized by low testosterone concentrations, occurring more commonly in men as they age. The International Prostate Symptom Score (IPSS) is used to categorize the severity of ...
Impact of price reductions, subsidies, or financial incentives on healthy food purchases and consumption: a systematic review and meta-analysis
(
Elsevier
, 2024 , Article)
Poor diets are a global concern and are linked with various adverse health outcomes. Healthier foods such as fruit and vegetables are often more expensive than unhealthy options. This study aimed to assess the effect of ...
Computational design of anti-cancer peptides tailored to target specific tumor markers
(
Springer Nature
, 2024 , Article)
Anti-cancer peptides (ACPs) are short peptides known for their ability to inhibit tumor cell proliferation, migration, and the formation of tumor blood vessels. In this study, we designed ACPs to target receptors often ...
Validation of a risk prediction model for COVID-19: the PERIL prospective cohort study.
(
Future Medicine
, 2023 , Article)
This study aims to perform an external validation of a recently developed prognostic model for early prediction of the risk of progression to severe COVID-19. Patients were recruited at their initial diagnosis at two ...