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Now showing items 1121-1130 of 1162
The mitochondria: A target of polyphenols in the treatment of diabetic cardiomyopathy
(
MDPI
, 2020 , Article)
Diabetic cardiomyopathy (DCM) is a constellation of symptoms consisting of ventricular dysfunction and cardiomyocyte disarray in the presence of diabetes. The exact cause of this type of cardiomyopathy is still unknown; ...
Assessing the burden of intestinal parasites affecting newly arrived immigrants in Qatar
(
BioMed Central
, 2016 , Article)
In the last decades, the enormous influx of immigrants to industrialized countries has led to outbreaks of parasitic diseases, with enteric infections being amongst the most frequently encountered. In its strategy to control ...
Genotype-phenotype correlation in patients with isovaleric acidaemia: comparative structural modelling and computational analysis of novel variants.
(
Oxford University Press (OUP)
, 2017 , Article)
Isovaleric acidaemia (IVA) is an autosomal recessive inborn error of leucine metabolism. It is caused by a deficiency in the mitochondrial isovaleryl-CoA dehydrogenase (IVD) enzyme. In this study, we investigated eight ...
Spatial modelling of contribution of individual level risk factors for mortality from Middle East respiratory syndrome coronavirus in the Arabian Peninsula.
(
Public Library of Science
, 2017 , Article)
Middle East respiratory syndrome coronavirus is a contagious respiratory pathogen that is contracted via close contact with an infected subject. Transmission of the pathogen has occurred through animal-to-human contact at ...
Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells
(
Impact Journals
, 2016 , Article)
Drug resistance of cancer cells is recognized as the primary cause of failure of chemotherapeutic treatment in most human cancers. Growing evidences support the idea that deregulated cellular metabolism is linked to such ...
Platelets as a Possible Reservoir of HCV And Predictor of Response to Treatment
(
SciTechnol
, 2016 , Article)
In the era of new Hepatitis C Virus (HCV) therapy, and the detection of
extrahepatic HCV reservoirs such as peripheral blood mononuclear
cells and platelets, it is important to understand the factors underlying
resistance ...
Positioning the Scholarship of Teaching and Learning Firmly in the Center of Health Promotion Pedagogy
(
SAGE Publications Inc.
, 2022 , Other)
Historically, the work of Scholarship of Teaching and Learning (SoTL) scholars has been grounded in multi-disciplinary connections to educational psychology and pedagogical research. SoTL research and commentary intends ...
The impact of ICCPR's Global Audit of Cardiac Rehabilitation: where are we now and where do we need to go?
(
Elsevier
, 2023 , Other)
Despite the global epidemic of cardiovascular disease and the well-established mitigating benefits of cardiovascular rehabilitation (CR), availability is known to be grossly insufficient, and little was known about the ...
Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia
(
Public Library of Science (USA)
, 2016 , Article)
Sideroblastic anemias are acquired or inherited anemias that result in a decreased ability to
synthesize hemoglobin in red blood cells and result in the presence of iron deposits in the
mitochondria of red blood cell ...
The cost-effectiveness of a patient centred pressure ulcer prevention care bundle: Findings from the INTACT cluster randomised trial.
(
Elsevier
, 2017 , Article)
Pressure ulcers are serious, avoidable, costly and common adverse outcomes of healthcare. To evaluate the cost-effectiveness of a patient-centred pressure ulcer prevention care bundle compared to standard care. Cost-effectiveness ...