College of Health Sciences: Recent submissions
Now showing items 241-260 of 1741
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Identification of Potential Inhibitors Targeting GTPase-Kirsten RAt Sarcoma Virus (K-Ras) Driven Cancers via E-Pharmacophore-Based Virtual Screening and Drug Repurposing Approach
( IMR Press Limited , 2023 , Article)Background: Mutations in the K-Ras gene are among the most frequent genetic alterations in various cancers, and inhibiting RAS signaling has shown promising results in treating solid tumors. However, finding effective drugs ... -
Patterns and trends of hepatitis C virus infection in Jordan: an observational study
( Frontiers Media SA , 2023 , Article)Background: Hepatitis C virus (HCV) infection levels in Jordan remain uncertain. No HCV national population-based survey has ever been conducted in the country. To meet the World Health Organization’s target of reducing ... -
The effectiveness and safety of palbociclib and ribociclib in stage IV HR+/HER-2 negative breast cancer: a nationwide real world comparative retrospective cohort study
( Frontiers Media SA , 2023 , Article)Introduction: Palbociclib and ribociclib are indicated in the first-line treatment of hormonal receptor-positive HER-2 negative (HR+/HER2- negative) advanced breast cancer. Although randomized-controlled trials (RCTs) ... -
Transforming cancer clinical trials: The integral role of artificial intelligence in electronic health records for efficient patient recruitment
( Elsevier , 2023 , Article)Healthcare is one of the sectors where artificial intelligence (AI) is currently viewed as a crucial driving factor. Patient care, medical research, and clinical trial enrollment could all significantly improve due to AI's ... -
Challenges in Managing Nonmotor Symptoms of Parkinson's Disease in Low-Resourced Settings with Unavailability of Newer Drugs
( John Wiley and Sons Inc , 2024 , Article)Nonmotor symptoms (NMS) are prevalent in people with Parkinson's disease (PD). They can be just as debilitating and challenging to manage as the motor symptoms that are often more well known. The available evidence supporting ... -
Genomic insights and advanced machine learning: characterizing autism spectrum disorder biomarkers and genetic interactions
( Springer , 2024 , Article)Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by altered brain connectivity and function. In this study, we employed advanced bioinformatics and explainable AI to analyze gene ... -
Congenital absence of appendix: a rare condition that could result in severe complications-a review of literature
( Oxford University Press , 2023 , Article)Acute appendicitis is the most frequent cause of abdominal pain and acute emergency surgeries, with a mortality risk of 6-7% at its onset. Since atypical deviations in these structures are rare, they can lead to diagnosis ... -
Rational design of a multivalent vaccine targeting arthropod-borne viruses using reverse vaccinology strategies
( Elsevier , 2024 , Article)Viruses transmitted by arthropods, such as Dengue, Zika, and Chikungunya, represent substantial worldwide health threats, particularly in countries like India. The lack of approved vaccines and effective antiviral therapies ... -
Redefining Postpartum Depression Treatment: The Clinical Potential of Zuranolone
( Elsevier , 2024 , Article)We write to bring to attention a pressing health concern: Postpartum Depression (PPD), which affects a significant 17% of mothers globally (Wang et al., 2021). This psychiatric condition manifests as intense mood swings, ... -
Chronic kidney diseases and the risk of colorectal cancer: A systematic review and meta-analysis
( Taylor and Francis Ltd. , 2023 , Article)Objective: We conducted this review to offer a comprehensive search and up-to-date overview of the currently available information about the probability risk of colorectal cancer among chronic kidney disease patients. ... -
Academic Entitlement Among Pharmacy Students in the Arab World: A Multi-National Exploratory Study
(2024 , Article)OBJECTIVE: The study's aim was to explore academic entitlement among pharmacy students in different pharmacy colleges in the Arab World and assess associated factors. METHODS: This study design was a cross-sectional survey. ... -
Functional Characterization of Novel MC4R Variants Identified in Two Unrelated Patients with Morbid Obesity in Qatar
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)The leptin–melanocortin pathway is pivotal in appetite and energy homeostasis. Pathogenic variants in genes involved in this pathway lead to severe early-onset monogenic obesity (MO). The MC4R gene plays a central role in ... -
Call for emergency action to restore dietary diversity and protect global food systems in times of COVID-19 and beyond: Results from a cross-sectional study in 38 countries
( Elsevier , 2023 , Article)Background The COVID-19 pandemic has revealed the fragility of the global food system, sending shockwaves across countries' societies and economy. This has presented formidable challenges to sustaining a healthy and ... -
Exploring Emotional Intelligence and Sociodemographics in Higher Education; the Imperative for Skills and Curriculum Development
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)There is increasing interest in understanding the nature and impact of emotional intelligence (EI) in educational institutions and the workplace since EI is associated with academic performance, career success, job ... -
Association between body weight misperception and snacking patterns among adolescents: a population-based cross-sectional study
( BioMed Central Ltd , 2023 , Article)Background Unhealthy snacking behaviors and body weight misperception are both significant concerns in adolescent health. Weight misperception are common among youth and may influence their motivation to engage in ... -
Influence of adolescents' and parental dietary knowledge on adolescents' body mass index (BMI), overweight/obesity in 2004-2015: a longitudinal study
( BioMed Central Ltd , 2023 , Article)Objective: The global epidemic of overweight/obesity in children and adolescents poses a significant public health threat. This longitudinal study aims to investigate the relationship between adolescents' and their parents' ... -
Corrigendum to “Toxic metals in packed rice: Effects of size, type, origin, packing season, and storage duration” [J. Food Compos. (2023) 104920]
( Academic Press Inc. , 2024 , Article)The authors regret to inform you that they missed putting the funding agency in this article. It would be great if you kindly add a section on Funding: The research work was co-funded by the President Intramural Research ... -
Advances in essential oils encapsulation: development, characterization and release mechanisms
( Taylor and Francis Ltd. , 2023 , Article Review)Recent developments in micro and nanoencapsulation are promising tools to encounter the different limitations of essential oil formulations, enhance their functionalities, and protect them from the external environmental ... -
Estimating protection afforded by prior infection in preventing reinfection: Applying the test-negative study design.
( Oxford University Press , 2023 , Article)The COVID-19 pandemic has highlighted the need to use infection testing databases to rapidly estimate effectiveness of prior infection in preventing reinfection ($P{E}_S$) by novel SARS-CoV-2 variants. Mathematical modeling ... -
Development and Evaluation of the International Council of Cardiovascular Prevention and Rehabilitation (ICCPR) Program Certification for Low-Resource Settings.
( Dove Press Ltd , 2023 , Article)Cardiac rehabilitation (CR) is a proven model of secondary prevention, but new sites, providing quality care, are needed in low-resource settings. This study (1) described the development of International Council of ...
