Now showing items 581-600 of 724

    • “Safe” Chitosan Zinc Oxide Nanocomposite Has Minimal Organ-Specific Toxicity on Early Stages of Zebrafish Development 

      Younes, Nadin; Pintus, Gianfranco; Al-Asmakh, Maha; Rasool, Kashif; Younes, Salma; ... more authors ( American Chemical Society , 2019 , Article)
      Marine biofouling is considered one of the most challenging issues affecting maritime industries worldwide. In this regard, traditional biocides, being used to combat biofouling, have high toxicity toward the aquatic system. ...
    • Sanguinarine Induces Apoptosis in Papillary Thyroid Cancer Cells via Generation of Reactive Oxygen Species. 

      Khan, Abdul Q; Mohamed, Elham A N; Hakeem, Ishrat; Nazeer, Aneeza; Kuttikrishnan, Shilpa; ... more authors ( MDPI , 2020 , Article)
      Sanguinarine (SNG), a natural compound with an array of pharmacological activities, has promising therapeutic potential against a number of pathological conditions, including malignancies. In the present study, we have ...
    • Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling. 

      Akhtar, Sabah; Achkar, Iman W; Siveen, Kodappully S; Kuttikrishnan, Shilpa; Prabhu, Kirti S; ... more authors ( Frontiers Media , 2019 , Article)
      Sanguinarine (SNG), a benzophenanthridine alkaloid, has displayed various anticancer abilities in several vivo and studies. However, the anticancer potential of SNG is yet to be established in multiple myeloma (MM), a ...
    • SARS-CoV-2 and immune-microbiome interactions: Lessons from respiratory viral infections 

      Farhan, Cyprian; Sohail, Muhammad Umar; Abdelhafez, Ibrahim; Salman, Salma; Attique, Zakria; ... more authors ( Elsevier , 2021 , Article)
      By the beginning of 2020, infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had rapidly evolved into an emergent worldwide pandemic, an outbreak whose unprecedented consequences highlighted ...
    • SARS-CoV-2 antibody-positivity protects against reinfection for at least seven months with 95% efficacy 

      Laith J., Abu-Raddad; Chemaitelly, Hiam; Coyle, Peter; Malek, Joel A.; Ahmed, Ayeda A.; ... more authors ( Elsevier , 2021 , Article)
      Background Reinfection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been documented, raising public health concerns. SARS-CoV-2 reinfections were assessed in a cohort of antibody-positive persons ...
    • SARS-CoV-2 infection among primary healthcare workers: a cross- sectional study 

      Qotba, Hamda; Hamed, Ehab; Alnuaimi, Ahmed; Saad, Azza; Nasrallah, Gheyath; ... more authors ( GERMS , 2021 , Article)
      Healthcare workers (HCWs) are critical to the healthcare system and are at an increased risk of SARS-CoV-2 infection. They may acquire infections from the community and their work settings. To date, the majority of the ...
    • SARS-CoV-2 infection and effects of age, sex, comorbidity, and vaccination among older individuals: A national cohort study 

      Mahmoud, Mai A.; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Hasan, Mohammad R.; ... more authors ( Wiley , 2023 , Article)
      Background: We investigated the contribution of age, coexisting medical conditions, sex, and vaccination to incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and of severe, critical, or ...
    • SARS-CoV-2 Infection and Smoking: What is the association? A brief review 

      Ishita, Gupta; Sohail, Muhammad Umar; Elzawawi, Khaled E.; Amarah, Ahmed H.; Vranic, Semir; ... more authors ( Elsevier , 2021 , Article)
      Susceptibility to severe illness from COVID-19 is anticipated to be associated with cigarette smoking as it aggravates the risk of cardiovascular and respiratory illness, including infections. This is particularly important ...
    • SARS-CoV-2 Infection Is at Herd Immunity in the Majority Segment of the Population of Qatar. 

      Al-Thani, Mohamed H; Farag, Elmoubasher; Bertollini, Roberto; Al Romaihi, Hamad Eid; Abdeen, Sami; ... more authors ( Oxford University Press , 2021 , Article)
      Qatar experienced a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic that disproportionately affected the craft and manual worker (CMW) population, who comprise 60% of the total population. This study ...
    • SARS-CoV-2 infection triggers more potent antibody-dependent cellular cytotoxicity (ADCC) responses than mRNA-, vector-, and inactivated virus-based COVID-19 vaccines 

      Zedan, Hadeel T.; Smatti, Maria K.; Al-Sadeq, Duaa W.; Al Khatib, Hebah A.; Nicolai, Eleonora; ... more authors ( Wiley , 2024 , Article)
      Neutralizing antibodies (NAbs) are elicited after infection and vaccination and have been well studied. However, their antibody-dependent cellular cytotoxicity (ADCC) functionality is still poorly characterized. Here, we ...
    • SARS-CoV-2 seroprevalence in the urban population of Qatar: An analysis of antibody testing on a sample of 112,941 individuals 

      Peter V., Coyle; Chemaitelly, Hiam; Ben Hadj Kacem, Mohamed Ali; Abdulla Al Molawi, Naema Hassan; El Kahlout, Reham Awni; ... more authors ( Elsevier , 2021 , Article)
      The study objective was to the assess level of detectable severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the urban population of Qatar. Antibody testing was performed on residual blood specimens ...
    • Screening and diagnostic testing protocols for HIV and Syphilis infections in health care setting in Qatar: Evaluation and recommendations 

      Nasrallah, Gheyath K.; Al-Buainain, Raniya; Younes, Nadin; Dargham, Soha R.; Al-Sadeq, Duaa W.; ... more authors ( Public Library of Science , 2023 , Article)
      Background HIV and Syphilis are common STIs, which have become a concern and burden on healthcare systems, as many infections go untreated and lead to potentially serious complications. HIV is usually diagnosed with Western ...
    • Screening Novel Molecular Targets of Metformin in Breast Cancer by Proteomic Approach. 

      Al-Zaidan, Lobna; El Ruz, Rasha Abu; Malki, Ahmed M. ( Frontiers Media , 2017 , Article)
      Metformin is a commonly prescribed antihyperglycemic drug, and has been investigated in vivo and in vitro for its effect to improve the comorbidity of diabetes and various types of cancers. Several studies investigated the ...
    • Screening the growth inhibition mechanism of sulfate reducing bacteria by chitosan/lignosulfonate nanocomposite (CS@LS) in seawater media 

      Kashif, Rasool; Pandey, Ravi P.; Rasheed, P. Abdul; Gomez, Tricia; Al-Absi, Enas S.; ... more authors ( Elsevier , 2021 , Article)
      Sulfate-reducing bacteria (SRBs) induced biofilm formation is a global industrial concern due to its role in the development of microbial-induced corrosion (MIC). Herein, we have developed a biodegradable chitosan/lignosulfonate ...
    • Senolytics in diseases: killing to survive 

      Massoud, Gaelle P.; Eid, Ali E.; Booz, George W.; Rached, Layale; Yabluchanskiy, Andriy; ... more authors ( Elsevier , 2023 , Book chapter)
      Since the discovery of cellular senescence in 1961, numerous studies have investigated the role of senescent cells in the pathogenesis of many chronic diseases. Cellular senescence, defined by irreversible cell cycle arrest, ...
    • Serious Games for Learning Among Older Adults With Cognitive Impairment: Systematic Review and Meta-analysis 

      Abd-Alrazaq, Alaa; Abuelezz, Israa; AlSaad, Rawan; Al-Jafar, Eiman; Ahmed, Arfan; ... more authors ( National library of medicine , 2023 , Article)
      BACKGROUND: Learning disabilities are among the major cognitive impairments caused by aging. Among the interventions used to improve learning among older adults are serious games, which are participative electronic games ...
    • Seroprevalence and incidence of hepatitis E virus among blood donors: A review. 

      Al-Sadeq, Duaa W.; Majdalawieh, Amin F.; Nasrallah, Gheyath K. ( Wiley , 2017 , Article)
      Hepatitis E virus (HEV) is an RNA virus with 4 main genotypes. HEV-1 and HEV-2 infect solely humans, while HEV-3 and HEV-4 infect humans and various animals such as pigs, deer, and rabbits. HEV-5 and HEV-6 infect mainly ...
    • Seroprevalence of hepatitis E virus (HEV) among male craft and manual workers in Qatar (2020–2021) 

      Nadin, Younes; Yassine, Hadi M.; Nizamuddin, Parveen Banu; Kourentzi, Katerina; Tang, Patrick; ... more authors ( Elsevier , 2023 , Article)
      BackgroundThe rapid growth of Qatar in the last two decades has attracted a large influx of immigrant craft and manual workers (CMWs) seeking employment in jobs associated with food handling, domestic service, and construction. ...
    • Seroprevalence of hepatitis E virus among blood donors in Qatar (2013-2016) 

      Nasrallah, Gheyath K.; Al Absi, Enas S.; Ghandour, Rula; Ali, Nadima H.; Taleb, Sara; ... more authors ( Wiley , 2017 , Article)
      BACKGROUND Hepatitis E virus (HEV) is an RNA virus transmitted mainly through zoonotic transmission or fecal–oral route. More than 80% of Qatar's population are expatriates, including many coming from hyperendemic ...
    • Seroprevalence of herpes simplex virus type 1 and type 2 among the migrant workers in Qatar 

      Nasrallah, Gheyath K.; Dargham, Soha R.; Al-Sadeq, Duaa W.; Amanullah, Fathima H.; Shurrab, Farah M.; ... more authors ( Springer , 2023 , Article)
      Background: Limited data exists on herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) infections in migrant populations. This study investigated HSV-1 and HSV-2 seroprevalences and associations among craft and manual ...