Biomedical Sciences: Recent submissions
Now showing items 1-20 of 64
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IDENTIFICATION AND FUNCTIONAL VALIDATION OF RARE MISSENSE VARIANTS IN PLXNA1 AS A CANDIDATE GENE FOR SEVERE EARLY-ONSET OBESITY
(2024 , Master Thesis)Childhood obesity is a pressing issue in Qatar, with a reported prevalence of 49% among school-aged children and adolescents. This complex problem involves a combination of genetic and environmental factors. Monogenic ... -
CHARACTERIZATION OF PATHOGEN-ASSOCIATED ANTIBODY PROFILES IN DIABETES MELLITUS-TYPE 2 PATIENTS USING IMMUNOPROTEOMICS APPROACH
(2024 , Master Thesis)Type 2 diabetes mellitus (T2DM) is a common health concern globally. 80% of diabetic patients are T2DM patients. T2DM can result in many serious complications. For instance, cardiovascular diseases, renal diseases, eye ... -
UNRAVELING THE MICROBIOME DIVERSITY AND DYNAMICS IN DIFFERENT SAMPLE TYPES DURING CORONAVIRUS INFECTIONS
(2024 , Master Thesis)Background: Mucosal immunity and gut microbiome influence respiratory diseases like those caused by coronaviruses (HCoV). This study explores the relationship between HCoV infection and the respiratory and gut microbiome. ... -
ASSESSMENT OF GNAS LOSS OF FUNCTION IN MONOGENIC OBESITY USING THE ZEBRAFISH MODEL
(2024 , Master Thesis)GNAS (Guanine Nucleotide-Binding Protein, Alpha Stimulating) is an imprinted gene that encodes the alpha subunit of the stimulatory G protein (Gs), which participates in the signaling of various G protein-coupled receptors. ... -
ANALYSIS OF MUTATIONS USING ANCIENT DNA GENOMES TO UNDERSTAND PATHOGENIC EMERGENCE AND DISEASE EVOLUTION
(2024 , Master Thesis)Paleogenomics, the study of ancient DNA, has revolutionized our comprehension of human history by providing access to genomic data spanning hundreds of thousands of years. High-throughput sequencing methods have enabled ... -
Dissecting the Role of Physical Activity and Sleep in Metabolically Healthy Obese Subjects: A National Study
(2024 , Master Thesis)In the last decade, researchers brought attention to a subgroup of obesity that has a lower risk of cardiometabolic abnormalities. Considering Qatar is one of the top-ranked countries in terms of obesity, this study aims ... -
Machine Learning Prediction of Cancer from The Publicly Available Dataset
(2024 , Master Thesis)Prostate cancer in the second most common cause of cancer in men around the world and in Qatar with a high incidence rate worldwide. This has resulted in an increased mortality rate, making prostate cancer a healthcare ... -
Quality Control and Regulatory Framework for Implementing Machine Learning in Clinical Diagnosis: The DNA Methylation Classifier in Pediatric Brain Tumors
(2024 , Master Thesis)Background: Accurately diagnosing CNS tumors is essential but difficult, with a notable risk of errors. To enhance diagnostic precision, the WHO now combines molecular data with traditional methods. While AI and ML ... -
INTERACTION BETWEEN CLOCK GENE AND LIFESTYLE FACTOR IN RELATION TO OBESITY RISK FACTOR
(2024 , Master Thesis)Background: Circadian rhythms regulate vital biological processes affecting metabolic pathways. Its dysregulation is associated with obesity, cardiovascular diseases, insulin resistance, and other signs of metabolic syndrome. ... -
MACHINE LEARNING PREDICTION OF DIABETES FROM A PUBLICLY AVAILABLE DATASET
(2024 , Professional Masters Project)A wide array of medical conditions necessitate invasive diagnostic techniques, with diabetes being one of the most well-known among them. To address this challenge, a predictive model was developed using a publicly available ... -
Dietary Quality, Meal Timing and Circadian Syndrome Among Adults Attending NHANES 2005-2016
(2023 , Master Thesis)Background: Apart from diet quality, meal timing and shift work have also emerged as risk factors for cardiometabolic disease and are associated with circadian rhythm disturbances. Circadian Syndrome (CircS) is a novel ... -
Dietary Patterns and Cognition among Qatari Adults
(2023 , Master Thesis)Objectives: To assess the association between dietary patterns and cognitive function among Qatari adults. Methods: In a cross-sectional analysis, data on 1,000 Qatari adults attending the Qatar Biobank Study (QBB) aged ... -
The impact of COVID-19 crisis on the testing process of the Primary Health Care Corporation (PHCC) Laboratories in state of Qatar
(2023 , Master Thesis)Introduction The global healthcare systems have been significantly impacted by the coronavirus COVID-19 pandemic. It was a public health emergency that affects many health care services, including primary health care and ... -
Exploring the Trait Emotional Intelligence Levels among Qatar University Students and Employees
(2023 , Master Thesis)Background: Emotional Intelligence (EI) has gained attention for its association with professional success and effective management, as higher EI can enhance job control, commitment, and organizational outcomes. Object ... -
Managing students with special educational needs; educator's perspective and training needs
(2023 , Master Thesis)Introduction: The number of students with special educational needs (SEN) who are able to attend higher education is increasing. Faculty members are the key players for the implementation of inclusion education and inclusion ... -
The Association between Dietary Patterns and Hypothyroidism in Adult Population
(2023 , Master Thesis)Background: The thyroid gland produces hormones that are essential for various body functions. Hypothyroidism occurs when the thyroid gland cannot produce enough hormones. Even though several studies have found associations ... -
Testing the Anticancer Effect of Matcha Using Zebrafish as an Animal Model
(2023 , Master Thesis)Cancer is the second leading cause of death worldwide. Triple-negative breast cancer (TNBC) patients show the poorest prognosis and survival and the highest metastasis prevalence among all breast cancer subtypes. Matcha ... -
DIFFERENTIAL EXPRESSION OF MICRORNAS BY ANTI-OBESITY TREATMENT SULFORAPHANE IN SKELETAL MUSCLE OF DIET-INDUCED OBESITY IN MICE
(2023 , Master Thesis)Background: Skeletal muscles account for 40-60% of total body weight and are responsible for 30% of resting metabolic rate. They are essential for metabolic homeostasis in the body as they provide the leading site for ... -
PROFILE OF LONG NON-CODING RNA IN RESPONSE TO SULFORAPHANE ANTI-OBESITY TREATMENT IN SKELETAL MUSCLES OF DIET INDUCED OBESITY MICE
(2023 , Master Thesis)Background: World Health Organization data reveal a rapid growth in obesity worldwide, making it a major public health concern. Obesity has been studied extensively in recent decades; however, it is still challenging due ... -
CHARACTERIZING WITHIN-HOST DIVERSITY IN SHORT-TERM AND VACCINATED COVID-19 PATIENTS
(2023 , Master Thesis)SARS-CoV-2 is the etiological agent of the ongoing COVID-19 pandemic, which has caused massive losses in human lives and strained global health resources. The ongoing vaccination campaigns in many countries have spurred ...
