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The Regulation of BRN3B in Adipocytes by Glucose and Insulin
(2014 , Master Thesis)
Obesity is the inappropriate accumulation of excess fat stored in the adipocytes of the adipose tissue. Understanding the molecular mechanisms that regulate the process of the preadipocyte to adipocyte conversion, adipogenesis, ...
Molecular Analysis of Campylobacter Jejuni Virulence Genes From Clinical Isolates In Qatar
(2014 , Master Thesis)
Background: Campylobacter jejuni is the main cause of gastroenteritis worldwide. Symptoms of C. jejuni infections range from asymptomatic to bloody diarrhea. Previous studies showed a strong association between diversity ...
Managing a Multicultural Diversity Workforce in the Medical Laboratory Environment at Hamad Medical Corporation (HMC)
(2014 , Master Thesis)
Governmental facilities are expected to provide public services to meet the demands of the society. Hamad Medical Corporation (HMC), being the main health care provider in Qatar is no difference. By 2030, Qatar aims to be ...
Molecular Epidemiology and Genotype Distribution of Human Papillomavirus Among Arab Women in State of Qatar
(2014 , Master Thesis)
Background: Human papillomavirus (HPV) are the most commonly known sexually transmitted agents. To date, few reports are available on distribution of most prevalent and variants types of HPV in Arab women. Therefore, the ...
ASSOCIATION BETWEEN INSULIN RESISTANCE AND NITRIC OXIDE IN HUMAN RETINAL MICROVASCULAR ENDOTHELIAL CELLS IN VITRO
(2015 , Master Thesis)
Diabetic retinopathy (DR) a major consequence of diabetes is considered the leading
cause of vision loss and blindness worldwide among working adults. Endothelial
dysfunction expediting imbalance in vascular homeostasis, ...
APPLICATION OF MALDI-TOF MASS SPECTROMETRY AS A TOOL FOR BIOTYPING OF B. MELITENSIS
(2015 , Master Thesis)
Background: Brucellosis is a global zoonosis caused by the bacteria of the genus Brucella a hazard group III pathogen. Typing of Brucella species is of great importance for understanding the epidemiology of the disease and ...
Brn-3b and PPARy Nuclear Receptor Expression in Adipose Tissue of Human Subjects
(2014 , Master Thesis)
Obesity rates have reached alarming heights globally, having more than doubled since the 1980's. Over 60% of diabetic patients are obese, and the increasing severity of the disease is associated with Type 2 Diabetes ...
Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes
(2015 , Master Thesis)
Background: Docosahexaenoic acid (DHA; omega-3 fatty acid) has been reported to have potential anti-obesity properties. Hypoxia is a condition that results from the excessive expansion of white adipose tissue resulting in ...
Discovery of Novel Pyridine Derivatives as Anti-Cancer Agents
(2015 , Master Thesis)
The International Agency for Research on Cancer indicated that cancer burden was raised in 2012 to 14.1 million incidence cases and 8.2 mortality cases. Consequently, novel approaches are urgently required for further ...
INVESTIGATING MOLECULAR PATHWAYS OF ROS-INDUCED PRO-INFLAMMATORY SENESCENCE IN PREADIPOCYTES
(2015 , Master Thesis)
Obesity has been associated with chronic low-grade inflammation, which is
considered to be a major cause for insulin resistance and type 2 diabetes (T2D). The
therapeutic interventions for T2D are lacking due to the ...