Oxidative Stress Markers In Gestational Diabetes Mellitus

Abstract

Oxidative stress is typically the result of an imbalance between the reactive oxygen species (ROS) and the antioxidant. The increased production of ROS could lead into some serious physiological problems on the cell, such as: damage of DNA, and peroxidation of lipids and proteins. Normal pregnancy is characterized by an increase of free radical production and lipoperoxidation towards the end of the pregnancy compared with normal non-pregnant women. It is expected that pregnant women with gestational diabetes mellitus (GDM) are highly susceptible of having some imbalance between ROS and antioxidant that could be proved by measuring the level of oxidative stress markers.