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المؤلفSalaheldin, Taher A.
المؤلفHusseiny, Sherif M.
المؤلفAl-Enizi, Abdullah M.
المؤلفElzatahry, Ahmed
المؤلفCowley, Alan H.
تاريخ الإتاحة2016-10-24T10:08:11Z
تاريخ النشر2016-03-03
اسم المنشورInternational Journal of Molecular Science
المعرّفhttp://dx.doi.org/10.3390/ijms17030329
الاقتباسSalaheldin, T.A.; Husseiny, S.M.; Al-Enizi, A.M.; Elzatahry, A.; Cowley, A.H. Evaluation of the Cytotoxic Behavior of Fungal Extracellular Synthesized Ag Nanoparticles Using Confocal Laser Scanning Microscope. Int. J. Mol. Sci. 2016, 17, 329.
معرّف المصادر الموحدhttp://hdl.handle.net/10576/4922
الملخصSilver nanoparticles have been synthesized by subjecting a reaction medium to a Fusarium oxysporum biomass at 28 °C for 96 h. The biosynthesized Ag nanoparticles were characterized on the basis of their anticipated peak at 405 nm using UV-Vis-NIR spectroscopy. Structural confirmation was evident from the characteristic X-ray diffraction (XRD) pattern, high-resolution transmission electron Microscopy (HRTEM) and the particle size analyzer. The Ag nanoparticles were of dimension 40 ± 5 nm and spherical in shape. The study mainly focused on using the confocal laser scanning microscope (CLSM) to examine the cytotoxic activities of fungal synthesized Ag nanoparticles on a human breast carcinoma cell line MCF7 cell, which featured remarkable vacuolation, thus indicating a potent cytotoxic activity.
راعي المشروعDeanship of Scientific Research at King Saud University for its funding this Prolific Research group (PRG-1436-14).
اللغةen
الناشرMDPI AG
الموضوعsilver nanoparticles
cytotoxicity
breast cancer
confocal laser scanning microcopy
العنوانEvaluation of the Cytotoxic Behavior of Fungal Extracellular Synthesized Ag Nanoparticles Using Confocal Laser Scanning Microscope
النوعArticle
رقم العدد3
رقم المجلد17
ESSN1422-0067
dc.accessType Open Access


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