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AuthorAjith, Saniha
AuthorAlmomani, Fares
AuthorElhissi, Abdelbary
AuthorHusseini, Ghaleb A.
Available date2024-03-13T05:14:57Z
Publication Date2023
Publication NameHeliyon
ResourceScopus
ISSN24058440
URIhttp://dx.doi.org/10.1016/j.heliyon.2023.e21227
URIhttp://hdl.handle.net/10576/52978
AbstractThe past decade has witnessed a breakthrough in novel strategies to treat cancer. One of the most common cancer treatment modalities is chemotherapy which involves administering anti-cancer drugs to the body. However, these drugs can lead to undesirable side effects on healthy cells. To overcome this challenge and improve cancer cell targeting, many novel nanocarriers have been developed to deliver drugs directly to the cancerous cells and minimize effects on the healthy tissues. The majority of the research studies conclude that using drugs encapsulated in nanocarriers is a much safer and more effective alternative than delivering the drug alone in its free form. This review provides a summary of the types of nanocarriers mainly studied for cancer drug delivery, namely: liposomes, polymeric micelles, dendrimers, magnetic nanoparticles, mesoporous nanoparticles, gold nanoparticles, carbon nanotubes and quantum dots. In this review, the synthesis, applications, advantages, disadvantages, and previous studies of these nanomaterials are discussed in detail. Furthermore, the future opportunities and possible challenges of translating these materials into clinical applications are also reported.
Languageen
PublisherElsevier
SubjectCancer therapy
Drug delivery
Nanocarriers
Nanomaterials
Nanomedicine
TitleNanoparticle-based materials in anticancer drug delivery: Current and future prospects
TypeArticle Review
Issue Number11
Volume Number9
dc.accessType Open Access


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