Phytochemical Analysis of Anastatica hierochuntica and Aerva javanica Grown in Qatar: Their Biological Activities and Identification of Some Active Ingredients
Date
2023-04-01Metadata
Show full item recordAbstract
Plant-derived compounds and their extracts are known to exhibit chemo preventive (antimicrobial, antioxidant and other) activities. The levels of such chemo preventive compounds vary depending on environmental factors, including the regions where they grow. Described in this study are: (i) a phytochemical analysis of the two plants grown in the desert environment of Qatar, viz., Anastatica hierochuntica and Aerva javanica; (ii) the antibacterial, antifungal and antioxidant activities of various solvent extracts of these plants; (iii) a report on the isolation of several pure compounds from these plants. The phytochemical screening indicated the presence of glycosides, tannins, flavonoids, terpenoids, saponins, phenol and anthraquinones in various extracts of each of the plants. Antibacterial and antioxidant activities were studied using agar diffusion and DPPH methods, respectively. The extracts of Anastatica hierochuntica as well as Aerva javanica inhibit the growth of both gram-positive and gram-negative bacterial species. Various extracts of the two plants also exhibited higher or similar antioxidant activities as those of the standard antioxidants, α-tocopherol and ascorbic acid. The extracts of these plants were further purified by HPLC and characterized by IR and NMR techniques. This process has led to identification of β-sitosterol, campesterol and methyl-9-(4-(3,4-dihydroxy-1′-methyl-5′-oxocyclohexyl)-2-hydroxycyclohexyl)nonanoate from Anastatica hierochuntica, and lupenone, betulinic acid, lupeol acetate and persinoside A and B from Aerva javanica. The results reported herein suggests that Anastatica hierochuntica and Aerva javanica are potent sources of phytomedicines.
Collections
- Chemistry & Earth Sciences [555 items ]
Related items
Showing items related by title, author, creator and subject.
-
Developing a Framework for Optimal Performance of Activated Carbon/ Graphene Oxide/Activated Carbon-Graphene Oxide Nano Adsorbent for the Removal of Antibiotics from Wastewater
Varde, Sunita Roshankumar (2021 , Master Thesis)Antibiotics are important drugs for treating infectious diseases and they have undoubtedly saved the lives of millions of people. A growing global problem is the emergence of antibiotic resistance, which means that the ... -
An Integrated Approach to Produced Water Treatment using Sand Filtration, Activated Carbon and Microemulsions modified Activated Carbon
Al-Kaabi, Maryam Ali; Al-Ghouti, Mohammad Ahmad; Zouari, Nabil A.; Ahmed, Talaat Abdelfattah ( Qatar University Press , 2021 , Poster)The produced water from natural gas production process in the North field offshore is considered as the largest wastewater volume in Qatar, which could be potentially used for clean water resources for the industry as well ... -
Validity of clinical disease activity index (CDAI) to evaluate the disease activity of rheumatoid arthritis patients in Sri Lanka: A prospective follow up study based on newly diagnosed patients
Dissanayake, Keerthie; Jayasinghe, Chandrika; Wanigasekara, Priyani; Dissanayake, Jayampathy; Sominanda, Ajith ( Public Library of Science , 2022 , Article)Routine use of the Disease Activity Score-28 (DAS28) to assess the disease activity in rheumatoid arthritis (RA) is limited due to its dependency on laboratory investigations and the complex calculations involved. In ...