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AuthorPountos, Ippokratis
AuthorTutar, Rumeysa
AuthorTellisi, Nazzar
AuthorDarabi, Mohammad Ali
AuthorHasan, Anwarul
AuthorAshammakhi, Nureddin
Available date2024-07-24T10:13:51Z
Publication Date2021
Publication NameDesign, Fabrication, and Characterization of Multifunctional Nanomaterials
ResourceScopus
URIhttp://dx.doi.org/10.1016/B978-0-12-820558-7.00008-X
URIhttp://hdl.handle.net/10576/57064
AbstractNanotechnology is a rapidly evolving field that promises to revolutionize several areas of clinical practice ranging from gene therapy, research, and drug delivery. One of the major difficulties of such advances reaching the clinic is the prolonged testing and inefficient preclinical models for testing. Recently, organ-on-a-chip systems have been developed, and they are microscale bioengineered systems capable of recapitulating complex organ functions in health and disease. They represent a valuable in vitro tool with applications in the study of treatment modalities for an wide range of conditions ranging from drug discovery to cancer treatment. The aim of this chapter is to discuss the development and evolution of organ-on-a-chip models in testing the safety, efficacy, and function of nanomaterials. This chapter will also further elaborate on future avenues of research and discuss the challenges that remain to be addressed.
Languageen
PublisherElsevier
SubjectMicrofluidics
Nanomaterials
Nanomedicine
Organ-on-a-chip
Tissue culture systems
TitleThe use of organ-on-a-chip methods for testing of nanomaterials
TypeBook chapter
Pagination147-161
dc.accessType Abstract Only


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