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Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish.
(
Frontiers Media
, 2019 , Article)
Ultrasonography is the most widely used imaging technique in cardiovascular medicine. In this technique, a piezoelectric crystal produces, sends, and receives high frequency ultrasound waves to the body to create an image ...
Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
(
Wiley
, 2020 , Article)
© 2020 Wiley Periodicals, Inc. Myosin-binding protein C 3 (MYBPC3) variants are the most common cause of hypertrophic cardiomyopathy (HCM). HCM is a complex cardiac disorder due to its significant genetic and clinical ...
Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model.
(
MDPI
, 2019 , Article)
Advanced oxidation processes (AOPs) have recently attracted great interest in water pollution management. Using the zebrafish embryo model, we investigated the environmental impacts of two thermally (RGOTi)- and hydrogen ...
Resveratrol Inhibits Oxidative Stress and Prevents Mitochondrial Damage Induced by Zinc Oxide Nanoparticles in Zebrafish (Danio rerio)
(
MDPI
, 2020 , Article)
Despite their wide industrial use, Zinc oxide (ZnO) nanoparticles (NPs) exhibit a high
toxic potential while concerns of their health-related risks are still present, urging additional in vivo
clarification studies. ...
Design and Microinjection of Morpholino Antisense Oligonucleotides and mRNA into Zebrafish Embryos to Elucidate Specific Gene Function in Heart Development
(
MyJove Corporation
, 2022 , Article)
The morpholino oligomer-based knockdown system has been used to identify the function of various gene products through loss or reduced expression. Morpholinos (MOs) have the advantage in biological stability over DNA oligos ...
Nanotechnology in medicine – our experiences
(
Macedonian Pharmaceutical Association
, 2022 , Article)
The success of design criteria for long-circulating drug delivery systems to support membrane receptor-ligand interaction and internalization has been limited and there is a need to develop smarter approaches for efficient ...
Zebrafish as a Model for Anticancer Nanomedicine Studies.
(
MDPI
, 2021 , Article Review)
Nanomedicine is a new approach to fight against cancer by the development of anticancer nanoparticles (NPs) that are of high sensitivity, specificity, and targeting ability to detect cancer cells, such as the ability of ...
Reduced Cardiotoxicity of Ponatinib-Loaded PLGA-PEG-PLGA Nanoparticles in Zebrafish Xenograft Model.
(
MDPI
, 2022 , Article)
Tyrosine kinase inhibitors (TKIs) are the new generation of anti-cancer drugs with high potential against cancer cells' proliferation and growth. However, TKIs are associated with severe cardiotoxicity, limiting their ...
Effect of Water-Pipe Smoking on the Normal Development of Zebrafish
(
MDPI
, 2021 , Article)
Background: Among all types of tobacco consumption,Water-Pipe Smoking (WPS) is the
most widely used in the Middle East and second-most in several other countries. The effect of WPS
on normal development is not yet fully ...
Computational Modeling of Motile Cilia-Driven Cerebrospinal Flow in the Brain Ventricles of Zebrafish Embryo.
(
MDPI
, 2022 , Article)
Motile cilia are hair-like microscopic structures which generate directional flow to provide fluid transport in various biological processes. Ciliary beating is one of the sources of cerebrospinal flow (CSF) in brain ...