تصفح Laboratory Animal Research Center حسب المؤلف "Bagga, Puneet"
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Cytokine- and chemokine-induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy
Bhat, Ajaz A.; Nisar, Sabah; Singh, Mayank; Ashraf, Bazella; Masoodi, Tariq; Prasad, Chandra P.; Sharma, Atul; Maacha, Selma; Karedath, Thasni; Hashem, Sheema; Yasin, Syed Besina; Bagga, Puneet; Reddy, Ravinder; Frennaux, Michael P.; Uddin, Shahab; Dhawan, Punita; Haris, Mohammad; Macha, Muzafar A.... more authors ... less authors ( Wiley , 2022 , Article Review)Colorectal cancer (CRC) is a predominant life-threatening cancer, with liver and peritoneal metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor, nurtures a local inflammatory environment ... -
Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy
Bhat, A.A.; Bhat, Ajaz A.; Nisar, Sabah; Maacha, Selma; Carneiro-Lobo, Tatiana Correa; Akhtar, Sabah; Siveen, Kodappully Sivaraman; Wani, Nissar A.; Rizwan, Arshi; Bagga, Puneet; Singh, Mayank; Reddy, Ravinder; Uddin, Shahab; Grivel, Jean Charles; Chand, Gyan; Frenneaux, Michael P.; Siddiqi, Mushtaq A.; Bedognetti, Davide; El-Rifai, Wael; Macha, Muzafar A.; Haris, Mohammad... more authors ... less authors ( BMC , 2021 , Article Review)Esophageal cancer (EC) is a disease often marked by aggressive growth and poor prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant metastases among patients with advanced disease account ... -
Genetic variations influence brain changes in patients with attention-deficit hyperactivity disorder
Yadav, Santosh K.; Bhat, Ajaz A.; Hashem, Sheema; Nisar, Sabah; Kamal, Madeeha; Syed, Najeeb; Temanni, Mohamed Ramzi; Gupta, Rakesh K.; Kamran, Saddat; Azeem, Muhammad Waqar; Srivastava, Amit K.; Bagga, Puneet; Chawla, Sanjeev; Reddy, Ravinder; Frenneaux, Michael P.; Fakhro, Khalid; Haris, Mohammad... more authors ... less authors ( Springer Nature , 2021 , Article Review)Attention-deficit hyperactivity disorder (ADHD) is a neurological and neurodevelopmental childhood-onset disorder characterized by a persistent pattern of inattentiveness, impulsiveness, restlessness, and hyperactivity. ... -
Genetics of glutamate and its receptors in autism spectrum disorder
Nisar, Sabah; Bhat, Ajaz A.; Masoodi, Tariq; Hashem, Sheema; Akhtar, Sabah; Ali, Tayyiba Akbar; Amjad, Sara; Chawla, Sanjeev; Bagga, Puneet; Frenneaux, Michael P.; Reddy, Ravinder; Fakhro, Khalid; Haris, Mohammad... more authors ... less authors ( Springer Nature , 2022 , Article Review)Autism spectrum disorder (ASD) is a neurodevelopmental impairment characterized by deficits in social interaction skills, impaired communication, and repetitive and restricted behaviors that are thought to be due to altered ... -
Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies
Nisar, Sabah; Bhat, Ajaz A.; Singh, Mayank; Karedath, Thasni; Rizwan, Arshi; Hashem, Sheema; Bagga, Puneet; Reddy, Ravinder; Jamal, Farrukh; Uddin, Shahab; Chand, Gyan; Bedognetti, Davide; El-Rifai, Wael; Frenneaux, Michael P.; Macha, Muzafar A.; Ahmed, Ikhlak; Haris, Mohammad... more authors ... less authors ( Frontiers Media , 2021 , Article Review)Circular RNAs (circRNAs) are an evolutionarily conserved novel class of non-coding endogenous RNAs (ncRNAs) found in the eukaryotic transcriptome, originally believed to be aberrant RNA splicing by-products with decreased ... -
miRNAs as novel immunoregulators in cancer
Saife N., Lone; Bhat, Ajaz A.; Wani, Nissar A.; Karedath, Thasni; Hashem, Sheema; Nisar, Sabah; Singh, Mayank; Bagga, Puneet; Das, Bhudev Chandra; Bedognetti, Davide; Reddy, Ravinder; Frenneaux, Michael P.; El-Rifai, Wael; Siddiqi, Mushtaq A.; Haris, Mohammad; Macha, Muzafar A.... more authors ... less authors ( Elsevier , 2021 , Article Review)The immune system is a well-known vital regulator of tumor growth, and one of the main hallmarks of cancer is evading the immune system. Immune system deregulation can lead to immune surveillance evasion, sustained cancer ... -
Role of NAD+ in regulating cellular and metabolic signaling pathways
Sara, Amjad; Nisar, Sabah; Bhat, Ajaz A.; Shah, Ab Rauf; Frenneaux, Michael P.; Fakhro, Khalid; Haris, Mohammad; Reddy, Ravinder; Patay, Zoltan; Baur, Joseph; Bagga, Puneet... more authors ... less authors ( Elsevier , 2021 , Article Review)BackgroundNicotinamide adenine dinucleotide (NAD+), a critical coenzyme present in every living cell, is involved in a myriad of metabolic processes associated with cellular bioenergetics. For this reason, NAD+ is often ... -
Ubiquitin-specific peptidase 37: an important cog in the oncogenic machinery of cancerous cells.
Chauhan, Ravi; Bhat, Ajaz A; Masoodi, Tariq; Bagga, Puneet; Reddy, Ravinder; Gupta, Ashna; Sheikh, Zahoor Ahmad; Macha, Muzafar A; Haris, Mohammad; Singh, Mayank... more authors ... less authors ( BMC , 2021 , Article Review)Protein ubiquitination is one of the most crucial posttranslational modifications responsible for regulating the stability and activity of proteins involved in homeostatic cellular function. Inconsistencies in the ...