Laboratory Animal Research Center: Recent submissions

Now showing items 101-109 of 109

    • Animal Health Monitoring Program (AHMP) of LARC 

      Shanmugakonar, Muralitharan; Abujassoum, Hamda; Khan, Imran; Al Naemi, Hamda (2017 , Poster)
      Animal health monitoring is important to maintain the health of the animals used for research purpose. Maintaining healthy research animals is the prime requisite for best research outcomes. Health monitoring is performed ...

    • Diagnostic Microbiology Laboratory Monitoring of LARC 

      Khan, Imran; Shanmugakonar, Muralitharan; Aboujassoum, Hamda; Al Naemi, Hamda (2017 , Poster)
      Microbial free environment of a research facility is critical to maintain animal health. Establishing Microbiological Monitoring Program is mandatory to assure the quality of the system. Microbiological monitoring involves ...

    • Environmental Health Monitoring Program (EHMP) of LARC 

      Shanmugakonar, Muralitharan; Abujassoum, Hamda; Khan, Imran; Al Naemi, Hamda (2017 , Poster)
      Routine environmental monitoring is the prime necessity to maintain a Specific Pathogen Free (SPF) facility. Monitoring the animals & its environment is important to control the contamination and outbreak of disease. ...

    • ANIMAL MODEL FOR CHILDHOOD OBESITY 

      Al-Naemi, Hamda; Das, Sandra Concepcion (2017 , Poster)
      Obesity has been recognized as a global health problem and linked with chronic diseases such as diabetes mellitus, cardiovascular syndromes, musculoskeletal disorders and some cancers. Children exposed to high carbohydrate, ...

    • Effect of CARMA 2sh gene in Mouse embryonic stem (ES) cells 

      Shanmugakonar, Muralitharan; Varadharajan, Kavitha; Vito, Pasquale (2017 , Poster)
      CARMA2 belongs to the CARMA family of proteins. They are involved in the regulation and activation of NF-κB that have a central role in the control of immune and inflammatory response, and cell survival and proliferation. ...

    • ENDOTHELIAL NITRIC OXIDE ACTIVITY & BIOAVAILABILITY DURING OBESITY CONDITIONS 

      Das, Sandra Concepcion; Al-Naemi, Hamda (2017 , Poster)
      Obesity has been recognized as a pandemic and linked with several metabolic dysfunctions. One of the hallmarks in the onset of obesity is the development of hypertension coupled with endothelial dysfunction. (ED) A fundamental ...

    • CARMA2sh and ULK2 control pathogen-associated molecular patterns recognition in human keratinocytes: psoriasis-linked CARMA2sh mutants escape ULK2 censorship 

      Scudiero, Ivan; Mazzone, Pellegrino; D'Andrea, Luca E.; Ferravante, Angela; Zotti, Tiziana; ... more authors ( Nature , 2017 , Article)
      The molecular complexes formed by specific members of the family of CARMA proteins, the CARD domain-containing adapter molecule BCL10 and MALT1 (CBM complex) represent a central hub in regulating activation of the pleiotropic ...

    • Expression of active and inactive forms of CIK and CARMA 2sh proteins in Normal Human Epidermal Keratinocytes (NHEK) 

      Shanmugakonar, Muralitharan; Varadharajan, Kavitha; Vito, Pasquale (2016 , Poster)
      Psoriasis is a debilitating skin disease affecting approximately 23% of human population. The disease is considered to have key genetic underpinning and genome wide association studies and meta analysis have identified ...

    • NF-κB Essential MOdulator (NEMO) Is Critical for Thyroid Function 

      Reale, Carla; Iervolino, Anna; Scudiero, Ivan; Ferravante, Angela; Egildo D, Luca; ... more authors ( American Society for Biochemistry and Molecular Biology , 2016 , Article)
      The I-κB kinase (IKK) subunit NEMO/IKKγ (NEMO) is an adapter molecule that is critical for canonical activation of NF-κB, a pleiotropic transcription factor controlling immunity, differentiation, cell growth, tumorigenesis ...