Browsing by Author "Souchelnytskyi, N."
Now showing items 1-5 of 5
-
A protocol for the detection of genetic markers in saliva by polymerase chain reaction without a nucleic acid purifi cation step: Examples of SARS-CoV-2 and GAPDH markers
Kannan, S.; Ericsson, J.; Souchelnytskyi, N.; Souchelnytskyi, S. ( Danylo Halytskyi Lviv National Medical University , 2021 , Article)Introduction. Polymerase chain reaction (PCR)-based diagnostic tests use purifi ed nucleic acids (NAs) from clinical samples. The NAs purifi cation step adds time, cost, and aff ects the quality of testing. The objective ... -
Application of nucleic acid amplification tests in managing COVID-19 pandemic
Souchelnytskyi, S.; Souchelnytskyi, N. ( Danylo Halytskyi Lviv National Medical University , 2020 , Article)Background. COVID-19 pandemic highlighted the importance of sensitive and specific tests that would be cost-efficient, fast and scalable. There are more than 200 COVID-19 detection tests available worldwide, with every ... -
Cell-based diagnostic of bronchial carcinoma: Case study of a diagnostic value of tests of circulating tumor cells and organoid culture
Souchelnytskyi, N.; Kost, A.; Souchelnytskyi, S. ( Danylo Halytskyi Lviv National Medical University , 2020 , Article)Diagnostic based on analysis of living tumor cells is frequently used in oncology. Circulating tumor cells in the blood and cells obtained from a tumor biopsy are used to access their carcinogenic properties and subsequently ... -
A LONG-TERM 10G-HYPERGRAVITY EXPOSURE PROMOTES CELL-CELL CONTACTS AND REDUCES ADHESIVENESS TO A SUBSTRATE, MIGRATION, AND INVASIVENESS OF MCF-7HUMAN BREAST CANCER CELLS.
Kannan, S; Shailesh, H; Mohamed, H; Souchelnytskyi, N; Souchelnytskyi, S ( Exp Oncol , 2022 , Article)G-force is a fundamental force controlling human cells. Cancer is one of the 4 major health challenges in the Space missions. Cancer in Space project evaluates the reaction of human cancer cells to the conditions of the ... -
Proteomics of transforming growth factor ?1 (TGF ?1) signaling in 184A1 human breast epithelial cells suggests the involvement of casein kinase 2? in TGF ?1-dependent p53 phosphorylation at Ser392
Woksepp, H.; Saini, R. K.R.; Zakharchenko, O.; Gautier, A.; Souchelnytskyi, N.; Souchelnytskyi, S.... more authors ... less authors ( Morion LLC , 2019 , Article)Aim: Transforming growth factor ?1 (TGF ?1) is a potent regulator of breast tumorigenesis. It inhibits proliferation of carcinoma cells, but the strength of its inhibitory action varies for cells from benigh, non-metastatic ...