Browsing by Author "Wehbe,Zena"
Now showing items 1-8 of 8
-
An updated overview of cyanidins for chemoprevention and cancer therapy
Posadino, Anna Maria; Giordo, Roberta; Ramli, Iman; Zayed, Hatem; Nasrallah, Gheyath K.; Wehbe, Zena; Eid, Ali H.; Gürer, Eda Sönmez; Kennedy, John F.; Aldahish, Afaf Ahmed; Calina, Daniela; Razis, Ahmad Faizal Abdull; Modu, Babagana; Habtemariam, Solomon; Sharifi-Rad, Javad; Pintus, Gianfranco; Cho, William C.... more authors ... less authors ( Elsevier , 2023 , Article Review)Anthocyanins are colored polyphenolic compounds that belong to the flavonoids family and are largely present in many vegetables and fruits. They have been used in traditional medicine in many cultures for a long time. The ... -
Dysregulation of angiotensin converting enzyme 2 expression and function in comorbid disease conditions possibly contributes to coronavirus infectious disease 2019 complication severity
Hammoud, Safaa H.; Wehbe, Zena; Abdelhady, Samar; Kobeissy, Firas; Eid, Ali H.; El-Yazbi, Ahmed F.... more authors ... less authors ( American Society for Pharmacology and Experimental Therapy , 2021 , Article Review)ACE2 has emerged as a double agent in the COVID-19 ordeal, as it is both physiologically protective and virally conducive. The identification of ACE2 in as many as 72 tissues suggests that extrapulmonary invasion and damage ... -
Estrogen and Bisphenol A in Hypertension
Wehbe, Zena; Nasser, Suzanne A.; El-Yazbi, Ahmed; Nasreddine, Salam; Eid, Ali H. ( Springer , 2020 , Article Review)Purpose of Review: Cardiovascular disease (CVD) is a non-subsiding disease that remains a leading cause of morbidity and mortality. CVD has been associated with endocrine disruptors, such as bisphenol A (BPA). This review ... -
Macrophage responses associated with COVID-19: A pharmacological perspective
Booz, George W.; Altara, Raffaele; Eid, Ali H.; Wehbe, Zena; Fares, Souha; Zaraket, Hassan; Habeichi, Nada J.; Zouein, Fouad A.... more authors ... less authors ( Elsevier , 2020 , Article)COVID-19 has caused worldwide death and economic destruction. The pandemic is the result of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has demonstrated high rates of infectivity leading to great ... -
Molecular and Biological Mechanisms Underlying Gender Differences in COVID-19 Severity and Mortality
Wehbe, Zena; Hammoud, Safaa Hisham; Yassine, Hadi M; Fardoun, Manal; El-Yazbi, Ahmed F; Eid, Ali H... more authors ... less authors ( Frontiers Media , 2021 , Article)Globally, over two million people have perished due to the recent pandemic caused by SARS-CoV-2. The available epidemiological global data for SARS-CoV-2 portrays a higher rate of severity and mortality in males. Analyzing ... -
Molecular Insights Into SARS COV-2 Interaction With Cardiovascular Disease: Role of RAAS and MAPK Signaling
Wehbe, Zena; Hammoud, Safaa; Soudani, Nadia; Zaraket, Hassan; El-Yazbi, Ahmed; Eid, Ali H.... more authors ... less authors ( Frontiers Media S.A. , 2020 , Article)In December 2019, reports of viral pneumonia came out of Wuhan city in Hubei province in China. In early 2020, the causative agent was identified as a novel coronavirus (CoV) sharing some sequence similarity with SARS-CoV ... -
Nano-targeting vascular remodeling in cancer: Recent developments and future directions
Roberta, Giordo; Wehbe, Zena; Paliogiannis, Panagiotis; Eid, Ali H.; Mangoni, Arduino A.; Pintus, Gianfranco... more authors ... less authors ( Elsevier , 2022 , Article Review)Tumor growth and progression are strictly dependent on the adequate blood supply of oxygen and nutrients. The formation of new blood vessels and vascular networks is essential to ensure this demand. Blood vessels also ... -
Repurposing Ivermectin for COVID-19: Molecular Aspects and Therapeutic Possibilities
Wehbe, Zena; Wehbe, Maya; Iratni, Rabah; Pintus, Gianfranco; Zaraket, Hassan; Yassine, Hadi M; Eid, Ali H... more authors ... less authors ( Frontiers Media , 2021 , Article)As of January 2021, SARS-CoV-2 has killed over 2 million individuals across the world. As such, there is an urgent need for vaccines and therapeutics to reduce the burden of COVID-19. Several vaccines, including mRNA, ...