Browsing by Author "Al-Kuwari, Einas"
Now showing items 1-20 of 31
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Addressing bias in the definition of SARS-CoV-2 reinfection: implications for underestimation
Chemaitelly, Hiam; Ayoub, Houssein H.; Tang, Patrick; Yassine, Hadi M.; Al Thani, Asmaa A.; Hasan, Mohammad R.; Coyle, Peter; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F.; Nasrallah, Gheyath K.; Al-Kuwari, Mohamed Ghaith; Butt, Adeel A.; Al-Romaihi, Hamad Eid; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J.... more authors ... less authors ( Frontiers Media , 2024 , Article)Introduction: Reinfections are increasingly becoming a feature in the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, accurately defining reinfection poses methodological ... -
Analytic comparison between three high-throughput commercial SARS-CoV-2 antibody assays reveals minor discrepancies in a high-incidence population
Nasrallah, Gheyath K; Dargham, Soha R; Shurrab, Farah; Al-Sadeq, Duaa W; Al-Jighefee, Hadeel; Chemaitelly, Hiam; Al Kanaani, Zaina; Al Khal, Abdullatif; Al Kuwari, Einas; Coyle, Peter; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Rahim, Hanan F Abdul; Yassine, Hadi M; Al Kuwari, Mohamed G; Qotba, Hamda; Al Romaihi, Hamad Eid; Tang, Patrick; Bertollini, Roberto; Al-Thani, Mohamed H; Althani, Asmaa A; Abu-Raddad, Laith J... more authors ... less authors ( Nature Research , 2021 , Article)Performance of three automated commercial serological IgG-based assays was investigated for assessing SARS-CoV-2 "ever" (past or current) infection in a population-based sample in a high exposure setting. PCR and serological ... -
Assessment of the Risk of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reinfection in an Intense Reexposure Setting
Abu-Raddad, Laith J.; Chemaitelly, Hiam; Malek, Joel A.; Ahmed, Ayeda A.; Mohamoud, Yasmin A.; Younuskunju, Shameem; Ayoub, Houssein H.; Al Kanaani, Zaina; Al Khal, Abdullatif; Al Kuwari, Einas; Butt, Adeel A.; Coyle, Peter; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul Rahim, Hanan F.; Yassine, Hadi M.; Al Kuwari, Mohamed G.; Al Romaihi, Hamad Eid; Al-Thani, Mohamed H.; Bertollini, Roberto... more authors ... less authors ( NLM (Medline) , 2021 , Article)BACKGROUND: Risk of reinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unknown. We assessed the risk and incidence rate of documented SARS-CoV-2 reinfection in a cohort of laboratory-confirmed ... -
Association of Prior SARS-CoV-2 Infection With Risk of Breakthrough Infection Following mRNA Vaccination in Qatar.
Abu-Raddad, Laith J; Chemaitelly, Hiam; Ayoub, Houssein H; Yassine, Hadi M; Benslimane, Fatiha M; Al Khatib, Hebah A; Tang, Patrick; Hasan, Mohammad R; Coyle, Peter; Al Kanaani, Zaina; Al Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul Rahim, Hanan F; Nasrallah, Gheyath K; Al Kuwari, Mohamed Ghaith; Butt, Adeel A; Al Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al Khal, Abdullatif; Bertollini, Roberto... more authors ... less authors ( American Medical Association , 2021 , Article)The effect of prior SARS-CoV-2 infection on vaccine protection remains poorly understood. To assess protection from SARS-CoV-2 breakthrough infection after mRNA vaccination among persons with vs without prior SARS-CoV-2 ... -
BNT162b2 and mRNA-1273 COVID-19 vaccine effectiveness against the SARS-CoV-2 Delta variant in Qatar.
Tang, Patrick; Hasan, Mohammad R; Chemaitelly, Hiam; Yassine, Hadi M; Benslimane, Fatiha M; Al Khatib, Hebah A; AlMukdad, Sawsan; Coyle, Peter; Ayoub, Houssein H; Al Kanaani, Zaina; Al Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul Rahim, Hanan F; Nasrallah, Gheyath K; Al Kuwari, Mohamed Ghaith; Al Romaihi, Hamad Eid; Butt, Adeel A; Al-Thani, Mohamed H; Al Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J... more authors ... less authors ( Nature Researc , 2021 , Article)With the global expansion of the highly transmissible SARS-CoV-2 Delta (B.1.617.2) variant, we conducted a matched test-negative case-control study to assess the real-world effectiveness of COVID-19 messenger RNA vaccines ... -
BNT162b2 antigen dose and SARS-CoV-2 omicron infection in adolescents
Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; Al Thani, Asmaa A.; Al-Khatib, Hebah A.; Hasan, Mohammad R.; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F.; Nasrallah, Gheyath K.; Al-Kuwari, Mohamed Ghaith; Al-Romaihi, Hamad Eid; Butt, Adeel A.; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J.... more authors ... less authors ( Elsevier , 2023 , Other)COVID-19 vaccine antigen dose might affect protection against SARS-CoV-2 infection,1, 2 but direct evidence to quantify this effect is absent. We conducted a matched, retrospective, cohort study using a regression ... -
Characterizing the effective reproduction number during the COVID-19 pandemic: Insights from Qatar’s experience
Bsat, Raghid; Chemaitelly, Hiam; Coyle, Peter; Tang, Patrick; Hasan, Mohammad R; Al Kanaani, Zaina; Al Kuwari, Einas; Butt, Adeel A; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Nasrallah, Gheyath K; Benslimane, Fatiha M; Al Khatib, Hebah A; Yassine, Hadi M; Al Kuwari, Mohamed G; Al Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al Kha, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J; Ayoub, Houssein H... more authors ... less authors ( International Society of Global Health , 2022 , Article)Background: The effective reproduction number, Rt, is a tool to track and understand epidemic dynamics. This investigation of Rt estimations was conducted to guide the national COVID-19 response in Qatar, from the onset ... -
Covid-19 Vaccine Protection among Children and Adolescents in Qatar.
Chemaitelly, Hiam; AlMukdad, Sawsan; Ayoub, Houssein H; Altarawneh, Heba N; Coyle, Peter; Tang, Patrick; Yassine, Hadi M; Al-Khatib, Hebah A; Smatti, Maria K; Hasan, Mohammad R; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar H; Latif, Ali N; Shaik, Riyazuddin M; Abdul-Rahim, Hanan F; Nasrallah, Gheyath K; Al-Kuwari, Mohamed G; Al-Romaihi, Hamad E; Butt, Adeel A; Al-Thani, Mohamed H; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J... more authors ... less authors ( Massachusetts Medical Society , 2022 , Article)The BNT162b2 vaccine against coronavirus disease 2019 (Covid-19) has been authorized for use in children 5 to 11 years of age and adolescents 12 to 17 years of age but in different antigen doses. We assessed the real-world ... -
Duration of immune protection of SARS-CoV-2 natural infection against reinfection.
Chemaitelly, Hiam; Nagelkerke, Nico; Ayoub, Houssein H; Coyle, Peter; Tang, Patrick; Yassine, Hadi M; Al-Khatib, Hebah A; Smatti, Maria K; Hasan, Mohammad R; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F; Nasrallah, Gheyath K; Al-Kuwari, Mohamed Ghaith; Butt, Adeel A; Al-Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J... more authors ... less authors ( Oxford University Press , 2022 , Article)The future of the SARS-CoV-2 pandemic hinges on virus evolution and duration of immune protection of natural infection against reinfection. We investigated duration of protection afforded by natural infection, the effect ... -
Effectiveness of two and three doses of COVID-19 mRNA vaccines against infection, symptoms, and severity in the pre-omicron era: A time-dependent gradient
Layan, Sukik; Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; Al Thani, Asmaa A.; Hasan, Mohammad R.; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F.; Nasrallah, Gheyath K.; Al-Kuwari, Mohamed Ghaith; Butt, Adeel A.; Al-Romaihi, Hamad Eid; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Bertollini, Roberto; Abdel-Rahman, Manar E.; Abu-Raddad, Laith J.... more authors ... less authors ( Elsevier , 2024 , Article)BackgroundVaccines were developed and deployed to combat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This study aimed to characterize patterns in the protection provided by the BNT162b2 and ... -
Effects of BA.1/BA.2 subvariant, vaccination, and prior infection on infectiousness of SARS-CoV-2 omicron infections.
Qassim, Suelen H; Chemaitelly, Hiam; Ayoub, Houssein H; AlMukdad, Sawsan; Tang, Patrick; Hasan, Mohammad R; Yassine, Hadi M; Al-Khatib, Hebah A; Smatti, Maria K; Abdul-Rahim, Hanan F; Nasrallah, Gheyath K; Al-Kuwari, Mohamed Ghaith; Al-Khal, Abdullatif; Coyle, Peter; Kaleeckal, Anvar Hassan; Shaik, Riyazuddin Mohammad; Latif, Ali Nizar; Al-Kuwari, Einas; Jeremijenko, Andrew; Butt, Adeel A; Bertollini, Roberto; Al-Romaihi, Hamad Eid; Al-Thani, Mohamed H; Abu-Raddad, Laith J... more authors ... less authors ( Oxford University Press , 2022 , Article)Compared to BA.1, BA.2 was associated with lower RT-qPCR cycle threshold (Ct) value-3.53 fewer cycles (95% CI: 3.46-3.60), signifying higher infectiousness. This may reflect higher viral load and/or longer duration of ... -
Epidemiological impact of prioritising SARS-CoV-2 vaccination by antibody status: Mathematical modelling analyses
Ayoub, H.H.; Ayoub, Houssein H.; Chemaitelly, Hiam; Makhoul, Monia; Al Kanaani, Zaina; Al Kuwari, Einas; Butt, Adeel A.; Coyle, Peter; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul Rahim, Hanan F.; Nasrallah, Gheyath K.; Yassine, Hadi M.; Al Kuwari, Mohamed G.; Al Romaihi, Hamad Eid; Al-Thani, Mohamed H.; Bertollini, Roberto; Al Khal, Abdullatif; Abu-Raddad, Laith J.... more authors ... less authors ( BMJ Publishing Group , 2021 , Article)Background Vaccines against SARS-CoV-2 have been developed, but their availability falls far short of global needs. This study aimed to investigate the impact of prioritising available doses on the basis of recipient ... -
Epidemiological investigation of the first 5685 cases of SARS-CoV-2 infection in Qatar, 28 February-18 April 2020
Al Kuwari, Hanan M.; Abdul Rahim, Hanan F.; Abu-Raddad, Laith J.; Abou-Samra, Abdul Badi; Al Kanaani, Zaina; Al Khal, Abdullatif; Al Kuwari, Einas; Al Marri, Salih; Al Masalmani, Muna; Al Romaihi, Hamad E.; Al Thani, Mohamed H.; Coyle, Peter V.; Latif, Ali N.; Owen, Robert; Bertollini, Roberto; Butt, Adeel Ajwad... more authors ... less authors ( BMJ Publishing Group , 2020 , Article)© Authors 2020 Objective To define the epidemiological curve of COVID-19 in Qatar and determine factors associated with severe or critical illness. Design Case series of first 5685 COVID-19 cases in Qatar. Setting and ... -
Immune Imprinting and Protection against Repeat Reinfection with SARS-CoV-2
Chemaitelly, Hiam; Ayoub, Houssein H.; Tang, Patrick; Hasan, Mohammad R.; Coyle, Peter; Yassine, Hadi M.; Al-Khatib, Hebah A.; Smatti, Maria K.; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar H.; Latif, Ali N.; Shaik, Riyazuddin M.; Abdul-Rahim, Hanan F.; Nasrallah, Gheyath K.; Al-Kuwari, Mohamed G.; Butt, Adeel A.; Al-Romaihi, Hamad E.; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J.... more authors ... less authors ( Massachusetts Medical Society , 2022 , Other)More than 2 years into the coronavirus disease 2019 (Covid-19) pandemic, the global population carries heterogeneous immune histories derived from various exposures to infection, viral variants, and vaccination.1 Evidence ... -
Introduction and expansion of the SARS-CoV-2 B.1.1.7 variant and reinfections in Qatar: A nationally representative cohort study
J. Abu-Raddad, Laith; Chemaitelly, Hiam; H. Ayoub, Houssein; Coyle, Peter; A. Malek, Joel; A. Ahmed, Ayeda; A. Mohamoud, Yasmin; Younuskunju, Shameem; Tang, Patrick; Al Kanaani, Zaina; Al Kuwari, Einas; A. Butt, Adeel; Jeremijenko, Andrew; Hassan Kaleeckal, Anvar; Nizar Latif, Ali; Mohammad Shaik, Riyazuddin; F. Abdul Rahim, Hanan; K. Nasrallah, Gheyath; M. Yassine, Hadi; Ghaith Al Kuwari, Mohamed; Eid Al Romaihi, Hamad; H. Al-Thani, Mohamed; Al Khal, Abdullatif; Bertollini, Roberto... more authors ... less authors ( Public Library of Science , 2021 , Article)Background The epidemiology of the SARS-CoV-2 B.1.1.7 (or Alpha) variant is insufficiently understood. This study’s objective was to describe the introduction and expansion of this variant in Qatar and to estimate the ... -
Long-term COVID-19 booster effectiveness by infection history and clinical vulnerability and immune imprinting: a retrospective population-based cohort study
Hiam, Chemaitelly; Ayoub, Houssein H; Tang, Patrick; Coyle, Peter; Yassine, Hadi M; Al Thani, Asmaa A; Al-Khatib, Hebah A; Hasan, Mohammad R; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F; Nasrallah, Gheyath K; Al-Kuwari, Mohamed Ghaith; Butt, Adeel A; Al-Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al-Khal, Abdullatif; Bertollini, Roberto; Faust, Jeremy Samuel; Abu-Raddad, Laith J... more authors ... less authors ( Elsevier , 2023 , Article)BackgroundLong-term effectiveness of COVID-19 mRNA boosters in populations with different previous infection histories and clinical vulnerability profiles is inadequately understood. We aimed to investigate the effectiveness ... -
mRNA-1273 COVID-19 vaccine effectiveness against the B.1.1.7 and B.1.351 variants and severe COVID-19 disease in Qatar
Chemaitelly, Hiam; Yassine, Hadi M.; Benslimane, Fatiha M.; Al Khatib, Hebah A.; Tang, Patrick; Hasan, Mohammad R.; Malek, Joel A.; Coyle, Peter; Ayoub, Houssein H.; Al Kanaani, Zaina; Al Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul Rahim, Hanan F.; Nasrallah, Gheyath K.; Al Kuwari, Mohamed Ghaith; Al Romaihi, Hamad Eid; Al-Thani, Mohamed H.; Al Khal, Abdullatif; Butt, Adeel A.; Bertollini, Roberto; Abu-Raddad, Laith J.... more authors ... less authors (2021 , Article)The SARS-CoV-2 pandemic continues to be a global health concern. The mRNA-1273 (Moderna) vaccine was reported to have an efficacy of 94.1% at preventing symptomatic COVID-19 due to infection with ‘wild-type’ variants in a ... -
Pfizer-BioNTech mRNA BNT162b2 Covid-19 vaccine protection against variants of concern after one versus two doses.
Abu-Raddad, Laith J; Chemaitelly, Hiam; Yassine, Hadi M; Benslimane, Fatiha M; Al Khatib, Hebah A; Tang, Patrick; Malek, Joel A; Coyle, Peter; Ayoub, Houssein H; Al Kanaani, Zaina; Al Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul Rahim, Hanan F; Nasrallah, Gheyath K; Al Kuwari, Mohamed Ghaith; Al Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al Khal, Abdullatif; Butt, Adeel A; Bertollini, Roberto... more authors ... less authors ( Oxford University Press , 2021 , Article)Strategies for rolling out vaccination against Coronavirus Disease 2019 (Covid-19) varied across countries. A key question is whether delaying administration of the second vaccine dose to vaccinate the largest number of ... -
Protection against the omicron variant from previous SARS-CoV-2 infection
Altarawneh, Heba N.; Chemaitelly, Hiam; Hasan, Mohammad R.; Ayoub, Houssein H.; Qassim, Suelen; AlMukdad, Sawsan; Coyle, Peter; Yassine, Hadi M.; Al-Khatib, Hebah A.; Benslimane, Fatiha M.; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar H.; Latif, Ali N.; Shaik, Riyazuddin M.; Abdul-Rahim, Hanan F.; Nasrallah, Gheyath K.; Al-Kuwari, Mohamed G.; Butt, Adeel A.; Al-Romaihi, Hamad E.; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Bertollini, Roberto; Tang, Patrick; Abu-Raddad, Laith J.... more authors ... less authors ( Massachusetts Medical Society , 2022 , Other)Natural infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits strong protection against reinfection with the B.1.1.7 (alpha),1,2 B.1.351 (beta),1 and B.1.617.2 (delta)3 variants. However, the ... -
Protection of Omicron sub-lineage infection against reinfection with another Omicron sub-lineage
Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; Al-Khatib, Hebah A.; Smatti, Maria K.; Hasan, Mohammad R.; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F.; Nasrallah, Gheyath K.; Al-Kuwari, Mohamed Ghaith; Butt, Adeel A.; Al-Romaihi, Hamad Eid; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J.... more authors ... less authors ( Nature Research , 2022 , Article)There is significant genetic distance between SARS-CoV-2 Omicron (B.1.1.529) variant BA.1 and BA.2 sub-lineages. This study investigates immune protection of infection with one sub-lineage against reinfection with the other ...