Browsing by Author "Crovella, Sergio"
Now showing items 21-40 of 70
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Docosahexaenoic Acid, a Key Compound for Enhancing Sensitization to Drug in Doxorubicin-Resistant MCF-7 Cell Line.
Crovella, Sergio; Ouhtit, Allal; Rahman, Shaikh Mizanoor; Rahman, Md Mizanur ( MDPI , 2023 , Article)Drug resistance is a well-known and significant obstacle in the battle against cancer, rendering chemotherapy treatments often ineffective. To improve the effectiveness of chemotherapy, researchers are exploring the use ... -
Effect of near-infrared and blue laser light on vero E6 cells SARS-CoV-2 infection model
Zupin, Luisa; Clemente, Libera; Fontana, Francesco; Crovella, Sergio ( Wiley , 2022 , Other)Photobiomodulation therapy (PBMT) employing laser light has been emerging as a safe strategy to challenge viruses. In this study the effect of blue and near-infrared (NIR) laser light was assessed in an in vitro model of ... -
Effect of Short Time of SARS-CoV-2 Infection in Caco-2 Cells.
Zupin, Luisa; Fontana, Francesco; Clemente, Libera; Ruscio, Maurizio; Ricci, Giuseppe; Crovella, Sergio... more authors ... less authors ( MDPI , 2022 , Article)Coronavirus disease 19 (COVID-19) clinical manifestations include the involvement of the gastrointestinal tract, affecting around 10% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected children. In ... -
Evaluation of residual infectivity after SARS-CoV-2 aerosol transmission in a controlled laboratory setting
Zupin, Luisa; Licen, Sabina; Milani, Margherita; Clemente, Libera; Martello, Lorenzo; Semeraro, Sabrina; Fontana, Francesco; Ruscio, Maurizio; Miani, Alessandro; Crovella, Sergio; Barbieri, Pierluigi... more authors ... less authors ( MDPI , 2021 , Article)Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is mainly transmitted through respiratory droplets, aerosols, or direct contact with fomites from an infected subject. It has been reported that SARS-CoV-2 ... -
Expression of the miR-9-5p, miR-125b-5p and its target gene NFKB1 and TRAF6 in childhood-onset systemic lupus erythematosus (cSLE)
Nascimento, Denise de Queiroga; da Silva, Isaura Isabelle Fonseca Gomes; Lima, Camilla Albertina Dantas; Cavalcanti, André de Souza; Roberti, Luciana Rodrigues; Queiroz, Rosane Gomes de Paula; Ferriani, Virginia Paes Leme; Crovella, Sergio; Carvalho, Luciana Martins de; Sandrin-Garcia, Paula... more authors ... less authors ( Taylor and Francis , 2022 , Article)Childhood- onset systemic lupus erythematosus (cSLE) is a multisystem inflammatory disease that can lead to severe clinical conditions resulting in early comorbidities. Several genetic, environmental, and immunological ... -
Fc Epsilon RI–Neuroimmune Interplay in Pruritus Triggered by Particulate Matter in Atopic Dermatitis Patients
Isaifan, Dina; Crovella, Sergio; Soubra, Lama; Al-Nesf, Maryam; Steinhoff, Martin ( MDPI , 2023 , Article Review)Atopic dermatitis (AD) is the most common chronic relapsing neuroinflammatory skin disease that is characterized by a complex and multifactorial pathophysiology. It reflects a profound interplay between genetic and ... -
FTIR Spectroscopy to Reveal Lipid and Protein Changes Induced on Sperm by Capacitation: Bases for an Improvement of Sample Selection in ART.
Pachetti, Maria; Zupin, Luisa; Venturin, Irene; Mitri, Elisa; Boscolo, Rita; D'Amico, Francesco; Vaccari, Lisa; Crovella, Sergio; Ricci, Giuseppe; Pascolo, Lorella... more authors ... less authors (2020 , Article)Although being a crucial step for Assisted Reproduction Technologies (ART) success, to date sperm selection is based only on morphology, motility and concentration characteristics. Considering the many possible alterations, ... -
Full-house nephropathy associated with high expression of SPATA5L1 due to a genetic pathogenic variant
De Carvalho, Luciana Martins; De Sousa, Graziella Ribeiro; Moura, Ronald; Saggioro, Fabiano; Facincani, Inalda; Costa, Roberto; Kahwage, Paola Pinheiro; De Paula Queiroz, Rosane Gomes; Valera, Elvis Terci; Crovella, Sergio; Sandrin-Garcia, Paula... more authors ... less authors ( Oxford University Press , 2022 , Article)DEAR EDITOR, Non-lupus full-house nephropathy is a diagnostic challenge of yet unknown aetiology that does not satisfy criteria for SLE classification . Spermatogenesis-associated protein 5-like protein 1 (SPATA5L1) is ... -
Hidradenitis Suppurativa: A Perspective on Genetic Factors Involved in the Disease.
Moltrasio, Chiara; Tricarico, Paola Maura; Romagnuolo, Maurizio; Marzano, Angelo Valerio; Crovella, Sergio ( MDPI , 2022 , Article)Hidradenitis Suppurativa (HS) is a chronic inflammatory skin disease of the pilosebaceous unit, clinically consisting of painful nodules, abscesses, and sinus tracts mostly in, but not limited to, intertriginous skin areas. ... -
Hiv-1 infection transcriptomics: Meta-analysis of cd4+ t cells gene expression profiles
Coelho, Antonio Victor Campos; Gratton, Rossella; de Melo, João Paulo Britto; Andrade-Santos, José Leandro; Guimarães, Rafael Lima; Crovella, Sergio; Tricarico, Paola Maura; Brandão, Lucas André Cavalcanti... more authors ... less authors ( MDPI , 2021 , Article Review)HIV-1 infection elicits a complex dynamic of the expression various host genes. High throughput sequencing added an expressive amount of information regarding HIV-1 infections and pathogenesis. RNA sequencing (RNA-Seq) is ... -
Holistic health record for Hidradenitis suppurativa patients.
Tricarico, Paola Maura; Moltrasio, Chiara; Gradišek, Anton; Marzano, Angelo V; Flacher, Vincent; Boufenghour, Wacym; von Stebut, Esther; Schmuth, Matthias; Jaschke, Wolfram; Gams, Matjaž; Boniotto, Michele; Crovella, Sergio... more authors ... less authors ( Nature Research , 2022 , Article)Hidradenitis suppurativa (HS) is a recurrent inflammatory skin disease with a complex etiopathogenesis whose treatment poses a challenge in the clinical practice. Here, we present a novel integrated pipeline produced by ... -
Host Response of Syrian Hamster to SARS-CoV-2 Infection including Differences with Humans and between Sexes
Castellan, Martina; Zamperin, Gianpiero; Franzoni, Giulia; Foiani, Greta; Zorzan, Maira; Drzewnioková, Petra; Mancin, Marzia; Brian, Irene; Bortolami, Alessio; Pagliari, Matteo; Oggiano, Annalisa; Vascellari, Marta; Panzarin, Valentina; Crovella, Sergio; Monne, Isabella; Terregino, Calogero; De Benedictis, Paola; Leopardi, Stefania... more authors ... less authors ( MDPI , 2023 , Article)The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has highlighted the importance of having proper tools and models to study the pathophysiology of emerging infectious diseases to test therapeutic ... -
Human Defensins from Antivirals to Vaccine Adjuvants: Rediscovery of the Innate Immunity Arsenal
Zupin, Luisa; Crovella, Sergio ( Bentham Science Publishers , 2022 , Other)Human defensins are a class of antimicrobial peptides, belonging to the innate immunity system. These peptides are expressed at the level of respiratory tract (both upper and lower) where they represent the first line of ... -
Impact of Sample Preparation Methods on Single-Cell X-ray Microscopy and Light Elemental Analysis Evaluated by Combined Low Energy X-ray Fluorescence, STXM and AFM
Merolle, Lucia; Pascolo, Lorella; Zupin, Luisa; Parisse, Pietro; Bonanni, Valentina; Gariani, Gianluca; Kenig, Sasa; Bedolla, Diana E.; Crovella, Sergio; Ricci, Giuseppe; Iotti, Stefano; Malucelli, Emil; Kourousias, George; Gianoncelli, Alessandra... more authors ... less authors ( MDPI , 2023 , Article)BACKGROUND: Although X-ray fluorescence microscopy is becoming a widely used technique for single-cell analysis, sample preparation for this microscopy remains one of the main challenges in obtaining optimal conditions for ... -
Impacts on Student Learning and Skills and Implementation Challenges of Two Student-Centered Learning Methods Applied in Online Education
soubra, lama; al Ghouti, Mohamed; Abu diyeh, Mohamed; Crovella, sergio; Abou saleh, Haissam ( MDPI , 2022 , Article)Online education became more prevalent during the COVID-19 pandemic in many countries around the world, including the Gulf Cooperation Council (GCC) countries. This study aims at assessing the impacts on learning and skills ... -
In silico analysis of molecular interactions between HIV-1 glycoprotein gp120 and TNF receptors
Neyla Maria Pereira, Alves; de Moura, Ronald Rodrigues; Bernardo, Lucas Coêlho; Agrelli, Almerinda; de Oliveira, Ana Sofia Lima Estevão; da Silva, Natália Pereira; Crovella, Sergio; Brandão, Lucas André Cavalcanti... more authors ... less authors ( Elsevier , 2021 , Article)Proinflammatory microenvironmental is crucial for the Human Immunodeficiency Virus Type 1 (HIV-1) pathogenesis. The viral glycoprotein 120 (gp120) must interact with the CD4+ T cell chemokine receptor (CCR5) and a co-receptor ... -
In vitro effects of photobiomodulation therapy on 50B11 sensory neurons: evaluation of cell metabolism, oxidative stress, mitochondrial membrane potential (MMP), and capsaicin-induced calcium flow
Zupin, Luisa; Barbi, Egidio; Sagredini, Raffaella; Ottaviani, Giulia; Crovella, Sergio; Celsi, Fulvio... more authors ... less authors ( Wiley , 2021 , Article)The analgesic properties of photobiomodulation therapy (PBMT) have been raising increasing interest in the clinical community due to the positive effects observed on patients, nevertheless the mechanistic basis of its ... -
Inflammation resolution in environmental pulmonary health and morbidity
Isaifan, Dina; Crovella, Sergio; Soubra, Lama ( Elsevier , 2022 , Other)NA -
A loss-of-function NCSTN mutation associated with familial Dowling Degos disease and hidradenitis suppurativa
de Oliveira, Ana Sofia Lima Estevao; de Siqueira, Roberta Cardoso; Nait-Meddour, Cécile; Tricarico, Paola Maura; Moura, Ronald; Agrelli, Almerinda; d'Adamo, Adamo Pio; Jamain, Stéphane; Crovella, Sergio; de Fátima Medeiros Brito, Maria; Boniotto, Michele; Brandão, Lucas André Cavalcanti... more authors ... less authors ( Wiley , 2023 , Article)Dowling Degos disease (DDD) is a rare autosomal dominant genodermatosis characterized by acquired, slowly progressive reticulated pigmented lesions primarily involving flexural skin areas. Mutations in KRT5, POGLUT-1 and ... -
Microalgae potential to protect from heavy metals-induced carcinogenicity
Hadjira, Hamai-Amara; Abou-Saleh, Haissam; A. Al-Ghouti, Mohammad; Crovella, Sergio; Saadaoui, Imen; Soubra, Lama... more authors ... less authors ( Elsevier , 2024 , Article)Toxic elements are present naturally in the environment; however, during the last century, their level has been continuously rising in the air, water, and soil due to anthropogenic activities, including urban runoff, ...