Browsing by Author "Graham, Barney S"
Now showing items 1-8 of 8
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Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B cell Responses to Influenza Hemagglutinin.
Andrews, Sarah F; Chambers, Michael J; Schramm, Chaim A; Plyler, Jason; Raab, Julie E; Kanekiyo, Masaru; Gillespie, Rebecca A; Ransier, Amy; Darko, Sam; Hu, Jianfei; Chen, Xuejun; Yassine, Hadi M; Boyington, Jeffrey C; Crank, Michelle C; Chen, Grace L; Coates, Emily; Mascola, John R; Douek, Daniel C; Graham, Barney S; Ledgerwood, Julie E; McDermott, Adrian B... more authors ... less authors ( Elsevier , 2019 , Article)Vaccine-induced memory B cell responses to evolving viruses like influenza A involve activation of pre-existing immunity and generation of new responses. To define the contribution of these two types of responses, we ... -
Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses.
Kanekiyo, Masaru; Joyce, M Gordon; Gillespie, Rebecca A; Gallagher, John R; Andrews, Sarah F; Yassine, Hadi M; Wheatley, Adam K; Fisher, Brian E; Ambrozak, David R; Creanga, Adrian; Leung, Kwanyee; Yang, Eun Sung; Boyoglu-Barnum, Seyhan; Georgiev, Ivelin S; Tsybovsky, Yaroslav; Prabhakaran, Madhu S; Andersen, Hanne; Kong, Wing-Pui; Baxa, Ulrich; Zephir, Kathryn L; Ledgerwood, Julie E; Koup, Richard A; Kwong, Peter D; Harris, Audray K; McDermott, Adrian B; Mascola, John R; Graham, Barney S... more authors ... less authors ( Nature Research , 2019 , Article)In the version of this article initially published, the labels (50 Å) above the scale bars in Fig. 1b were incorrect. The correct size is 50 nm. The error has been corrected in the HTML and PDF versions of the article. -
Comparative Serological Study for the Prevalence of Anti-MERS Coronavirus Antibodies in High- and Low-Risk Groups in Qatar
Al Kahlout, Reham; Nasrallah, Gheyath; Farag, Elmoubasher; Wang, Lingshu; Lattwein, Erik; Müller, Marcel; El Zowalaty, Mohamed; Al Romaihi, Hamad; Graham, Barney; Al Thani, Asmaa; Yassine, Hadi... more authors ... less authors ( Hindawi Publishing Corporation , 2019 , Article)Infection with Middle East respiratory syndrome coronavirus (MERS-CoV) could be asymptomatic or cause mild influenza-like illness. Therefore, the prevalence of MERS-CoV infections in the general population could be ... -
Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages.
Corbett, Kizzmekia S; Moin, Syed M; Yassine, Hadi M; Cagigi, Alberto; Kanekiyo, Masaru; Boyoglu-Barnum, Seyhan; Myers, Sky I; Tsybovsky, Yaroslav; Wheatley, Adam K; Schramm, Chaim A; Gillespie, Rebecca A; Shi, Wei; Wang, Lingshu; Zhang, Yi; Andrews, Sarah F; Joyce, M Gordon; Crank, Michelle C; Douek, Daniel C; McDermott, Adrian B; Mascola, John R; Graham, Barney S; Boyington, Jeffrey C... more authors ... less authors ( American Society for Microbiology , 2019 , Article)Influenza vaccines targeting the highly conserved stem of the hemagglutinin (HA) surface glycoprotein have the potential to protect against pandemic and drifted seasonal influenza viruses not covered by current vaccines. ... -
Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses.
Boyoglu-Barnum, Seyhan; Hutchinson, Geoffrey B; Boyington, Jeffrey C; Moin, Syed M; Gillespie, Rebecca A; Tsybovsky, Yaroslav; Stephens, Tyler; Vaile, John R; Lederhofer, Julia; Corbett, Kizzmekia S; Fisher, Brian E; Yassine, Hadi M; Andrews, Sarah F; Crank, Michelle C; McDermott, Adrian B; Mascola, John R; Graham, Barney S; Kanekiyo, Masaru... more authors ... less authors ( Nature Research , 2020 , Article)The conserved hemagglutinin (HA) stem has been a focus of universal influenza vaccine efforts. Influenza A group 1 HA stem-nanoparticles have been demonstrated to confer heterosubtypic protection in animals; however, the ... -
Level of Maternal Respiratory Syncytial Virus (RSV) F Antibodies in Hospitalized Children and Correlates of Protection.
Taleb, Sara A; Al-Ansari, Khalid; Nasrallah, Gheyath K; Elrayess, Mohamed A; Al-Thani, Asmaa A; Derrien-Colemyn, Alexandrine; Ruckwardt, Tracy J; Graham, Barney S; Yassine, Hadi M... more authors ... less authors (2021)RSV is a major cause of lower respiratory infections among children, where no vaccine is available. The stabilized form of the fusion (F) protein, pre-F, is a leading vaccine candidate targeting different populations, ... -
Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses.
Kanekiyo, Masaru; Joyce, M Gordon; Gillespie, Rebecca A; Gallagher, John R; Andrews, Sarah F; Yassine, Hadi M; Wheatley, Adam K; Fisher, Brian E; Ambrozak, David R; Creanga, Adrian; Leung, Kwanyee; Yang, Eun Sung; Boyoglu-Barnum, Seyhan; Georgiev, Ivelin S; Tsybovsky, Yaroslav; Prabhakaran, Madhu S; Andersen, Hanne; Kong, Wing-Pui; Baxa, Ulrich; Zephir, Kathryn L; Ledgerwood, Julie E; Koup, Richard A; Kwong, Peter D; Harris, Audray K; McDermott, Adrian B; Mascola, John R; Graham, Barney S... more authors ... less authors ( Nature Research , 2019 , Article)The present vaccine against influenza virus has the inevitable risk of antigenic discordance between the vaccine and the circulating strains, which diminishes vaccine efficacy. This necessitates new approaches that provide ... -
Use of Hemagglutinin Stem Probes Demonstrate Prevalence of Broadly Reactive Group 1 Influenza Antibodies in Human Sera.
Yassine, Hadi M; McTamney, Patrick M; Boyington, Jeffery C; Ruckwardt, Tracy J; Crank, Michelle C; Smatti, Maria K; Ledgerwood, Julie E; Graham, Barney S... more authors ... less authors ( Nature Publishing Group , 2018 , Article)A better understanding of the seroprevalence and specificity of influenza HA stem-directed broadly neutralizing antibodies (bNAbs) in the human population could significantly inform influenza vaccine design efforts. Here, ...