تصفح حسب المؤلف "Aditya, M."
-
Exome sequence analysis of rare frequency variants in Late-Onset Alzheimer Disease
Sundarrajan, Sudharsana; Venkatesan, Arthi; Kumar S, Udhaya; Gopikrishnan, Mohanraj; Tayubi, Iftikhar Aslam; Aditya, M.; Siddaiah, Gowrishankar Bychapur; George Priya Doss, C.; Zayed, Hatem... more authors ... less authors ( Springer Nature , 2023 , Article)Alzheimer disease (AD) is a leading cause of dementia in elderly patients who continue to live between 3 and 11 years of diagnosis. A steep rise in AD incidents is observed in the elderly population in East-Asian countries. ... -
SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways.
Majeed, Yasser; Halabi, Najeeb; Madani, Aisha Y; Engelke, Rudolf; Bhagwat, Aditya M; Abdesselem, Houari; Agha, Maha V; Vakayil, Muneera; Courjaret, Raphael; Goswami, Neha; Hamidane, Hisham Ben; Elrayess, Mohamed A; Rafii, Arash; Graumann, Johannes; Schmidt, Frank; Mazloum, Nayef A... more authors ... less authors ( Nature Research , 2021 , Article)The NAD-dependent deacetylase SIRT1 controls key metabolic functions by deacetylating target proteins and strategies that promote SIRT1 function such as SIRT1 overexpression or NAD boosters alleviate metabolic complications. ...