Browsing by Author "Munusamy, Shankar"
Now showing items 1-5 of 5
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AMPK Activation Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro
Allouch, Soumaya; Munusamy, Shankar ( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Background: Chronic kidney disease (CKD) is characterized by progressive decline in renal function; if left untreated, it ultimately results in end-stage renal disease (ESRD), a condition that demands either dialysis or ... -
Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma
Munusamy, Shankar; Gopalakrishnan, Akila; Ravindran, Sreenithya; Alali, Feras; Eid, Ali H. ( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Background and Objectives: Renal cell carcinoma is the most common and lethal form of all renal cancers, and accounts for 4.1% of all cancer cases in Qatar. Mutations to Von-Hippel Lindeau (VHL) gene in renal cells activates ... -
Comparison Of In Vitro Models Of Diabetic Nephropathy Using Renal Tubular Cells
El Gamal, Heba; Munusamy, Shankar ( Hamad bin Khalifa University Press (HBKU Press) , 2014 , Conference Paper)Background: Diabetic nephropathy (DN) is a chronic and serious complication associated with diabetes. The standardization of an in vitro model to best represent DN is very challenging due to the chronic nature of the ... -
Role of methylglyoxal in diabetic cardiovascular and kidney diseases: Insights from basic science for application into clinical practice
Sankaralingam, Sowndramalingam; Ibrahim, Angham; Rahman, M. D.Mizanur; Eid, Ali H.; Munusamy, Shankar ( Bentham Science Publishers , 2018 , Other)Background: The incidence and prevalence of diabetes mellitus are increasing globally at alarming rates. Cardiovascular and renal complications are the major cause of morbidity and mortality in patients with diabetes. ... -
Synthesis And Pharmacological Screening Of Novel Piperine Analogs For Potential In Vitro Protection From Endoplasmic Reticulum Stress
Samir Hammad, Ayat; Munusamy, Shankar; Khalil, Ashraf ( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Background: The endoplasmic reticulum (ER) is the chief organelle involved in protein homeostasis. Perturbations to the ER protein folding machinery caused by hyperlipidemia, hyperglycemia or hypoglycemia has been shown ...