Browsing by Author "Mahmoud, Hesham"
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Trends in oral anticoagulant use in Qatar: a 5-year experience
Elewa Hazem; Alhaddad, Amani; Al-Rawi, Safa; Nounou, Amir; Mahmoud, Hesham; Singh, Rajvir... more authors ... less authors ( Springer New York LLC , 2017 , Article)In Qatar, dabigatran was introduced in 2011 followed by rivaroxaban in 2014. In this study, we aim to explore the trends in oral anticoagulant use in Qatar over the past 5 years and to what extent did DOACs replace warfarin. ... -
Warfarin-Rifampin-Gene (WARIF-G) Interaction: A Retrospective, Genetic, Case–Control Study
Salem, Muhammad; El-Bardissy, Ahmed; Elshafei, Mohamed Nabil; Khalil, Ahmed; Mahmoud, Hesham; Fahmi, Amr Mohamed; Kasem, Mohamed; Bader, Loulia; Sherbash, Mohamed; Elawady, Mostafa Ibrahim; Abdalazim, Walaa; Howady, Faraj; Elewa, Hazem... more authors ... less authors ( Wiley-Blackwell , 2023 , Article)Warfarin is extensively metabolized by cytochrome P450 2C9 (CYP2C9). Concomitant use with the potent CYP2C9 inducer, rifampin, requires close monitoring and dosage adjustments. Although, in theory, warfarin dose increase ...