تصفح حسب المؤلف "Shaito, Abdullah"
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Potential Adverse Effects of Resveratrol: A Literature Review.
Shaito, Abdullah; Posadino, Anna Maria; Younes, Nadin; Hasan, Hiba; Halabi, Sarah; Alhababi, Dalal; Al-Mohannadi, Anjud; Abdel-Rahman, Wael M; Eid, Ali H; Nasrallah, Gheyath K; Pintus, Gianfranco... more authors ... less authors ( MDPI , 2020 , Article Review)Due to its health benefits, resveratrol (RE) is one of the most researched natural polyphenols. Resveratrol's health benefits were first highlighted in the early 1990s in the French paradox study, which opened extensive ... -
Resveratrol-mediated regulation of mitochondria biogenesis-associated pathways in neurodegenerative diseases: molecular insights and potential therapeutic applications.
Shaito, Abdullah; Al-Mansoob, Maryam; Ahmad, Salma M S; Haider, Mohammad Z; Eid, Ali H; Posadino, Anna Maria; Pintus, Gianfranco; Giordo, Roberta... more authors ... less authors ( Bentham Science Publisher , 2022 , Article Review)Neurodegenerative disorders include neurological conditions that affect nerve cells, causing the progressive loss of their functions and ultimately leading to loss of mobility, coordination, and mental functioning. The ... -
Role of RhoA and Rho-associated kinase in phenotypic switching of vascular smooth muscle cells: Implications for vascular function
Tedy, Sawma; Shaito, Abdullah; Najm, Nicolas; Sidani, Munir; Orekhov, Alexander; El-Yazbi, Ahmed F.; Iratni, Rabah; Eid, Ali H.... more authors ... less authors ( Elsevier , 2022 , Article Review)Cardiovascular disease (CVD) continues to be the primary cause of global mortality. Vascular smooth muscle cells (VSMCs) are integral components of vascular structure and function, evident by their vital roles in modulating ... -
SARS-CoV-2 involvement in central nervous system tissue damage
Haidar, Muhammad Ali; Shakkour, Zaynab; Reslan, Mohammad Amine; Al-Haj, Nadine; Chamoun, Perla; Habashy, Karl; Kaafarani, Hasan; Shahjouei, Shima; Farran, Sarah H; Shaito, Abdullah; Saba, Esber S; Badran, Bassam; Sabra, Mirna; Kobeissy, Firas; Bizri, Maya... more authors ... less authors ( Wolters Kluwer , 2022 , Article Review)As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread globally, it became evident that the SARS-CoV-2 virus infects multiple organs including the brain. Several clinical studies revealed ... -
Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms
Hasan, Slika; Mansour, Hadi; Wehbe, Nadine; Nasser, Suzanne A.; Iratni, Rabah; Nasrallah, Gheyath; Shaito, Abdullah; Ghaddar, Tarek; Kobeissy, Firas; Eid, Ali H.... more authors ... less authors ( Elsevier , 2022 , Article)Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants have attracted attention as emerging therapeutic ... -
Traumatic Brain Injury Can Affect Emotions and Behaviors
Shakkour, Zaynab; Habashy, Karl John; Haidar, Muhammad Ali; Nasrallah, Leila; Tabet, Maha; Yehya, Yara; Sarieddine, Rana; El Hayek, Samer; Shaito, Abdullah; Kobeissy, Firas... more authors ... less authors ( Frontiers Media , 2023 , Article)Proper brain functioning is responsible for our feelings, behavior, and thinking. However, an injury to the brain can disrupt brain function, which can affect our emotions and behaviors. A traumatic brain injury (TBI) can ... -
Ubiquitin-Related Modifier 1 (URM-1) Modulates Cx43 in Breast Cancer Cell Lines.
El-Hajjar, Layal; Saliba, Jessica; Karam, Mario; Shaito, Abdullah; El Hajj, Hiba; El-Sabban, Marwan... more authors ... less authors ( MDPI , 2023 , Article)Gap-junction-forming connexins are exquisitely regulated by post-translational modifications (PTMs). In particular, the PTM of connexin 43 (Cx43), a tumor suppressor protein, regulates its turnover and activity. Here, we ... -
Unveiling a Biomarker Signature of Meningioma: the Need for a Panel of Genomic, Epigenetic, Proteomic, and RNA Biomarkers to Advance Diagnosis and Prognosis
Halabi, Reem; Dakroub, Fatima; Haider, Mohammad Z.; Patel, Stuti; Amhaz, Nayef A.; Reslan, Mohammad A.; Eid, Ali H.; Mechref, Yehia; Darwiche, Nadine; Kobeissy, Firas H.; Omeis, Ibrahim; Shaito, Abdullah... more authors ... less authors ( preprints , 2023 , Preprint)Meningiomas are the most prevalent primary intracranial tumors. The majority are benign but can undergo dedifferentiation in grades classified from I to III. Meningiomas tremendous variability in tumor behavior and slow ... -
Western and ketogenic diets in neurological disorders: can you tell the difference?
Habashy, Karl John; Ahmad, Fatima; Ibeh, Stanley; Mantash, Sarah; Kobeissy, Fatima; Issa, Hawraa; Habis, Ralph; Tfaily, Ali; Nabha, Sanaa; Harati, Hayat; Reslan, Mohammad Amine; Yehya, Yara; Barsa, Chloe; Shaito, Abdullah; Zibara, Kazem; El-Yazbi, Ahmed F; Kobeissy, Firas H... more authors ... less authors ( International Life Sciences Institute , 2022 , Article)The prevalence of obesity tripled worldwide between 1975 and 2016, and it is projected that half of the US population will be overweight by 2030. The obesity pandemic is attributed, in part, to the increasing consumption ... -
XPC multifaceted roles beyond DNA damage repair: p53-dependent and p53-independent functions of XPC in cell fate decisions
Abir, Zebian; El-Dor, Maya; Shaito, Abdullah; Mazurier, Frédéric; Rezvani, Hamid Reza; Zibara, Kazem... more authors ... less authors ( Elsevier , 2022 , Article)Xeroderma pigmentosum group C protein (XPC) acts as a DNA damage recognition factor for bulky adducts and as an initiator of global genome nucleotide excision repair (GG-NER). Novel insights have shown that the role of XPC ... -
Ziziphus nummularia: A Comprehensive Review of Its Phytochemical Constituents and Pharmacological Properties
Mesmar, Joelle; Abdallah, Rola; Badran, Adnan; Maresca, Marc; Shaito, Abdullah; Baydoun, Elias... more authors ... less authors ( MDPI , 2022 , Article Review)Ziziphus nummularia, a small bush of the Rhamnaceae family, has been widely used in traditional folk medicine, is rich in bioactive molecules, and has many reported pharmacological and therapeutic properties. Objective: ...