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Claudin-1, A Double-Edged Sword in Cancer.
(
MDPI
, 2020 , Article Review)
Claudins, a group of membrane proteins involved in the formation of tight junctions, are mainly found in endothelial or epithelial cells. These proteins have attracted much attention in recent years and have been implicated ...
Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications
(
MDPI
, 2020 , Article Review)
Vitamin D and its active metabolites are important nutrients for human skeletal health. UV irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the liver and kidneys into its active form, ...
GATA-3 as a potential therapeutic target for insulin resistance and type 2 diabetes mellitus.
(
PubMed Central
, 2020 , Article Review)
Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes as it leads to ectopic fat deposition. The anti-adipogenic transcription factor GATA-3 was ...
Advances in Cardiovascular Biomarker Discovery.
(
MDPI
, 2020 , Article Review)
Cardiovascular diseases are the leading causes of mortality worldwide. Among them, hypertension and its pathological complications pose a major risk for the development of other cardiovascular diseases, including heart ...
Molecular Mechanisms of Colon Cancer Progression and Metastasis: Recent Insights and Advancements.
(
MDPI
, 2020 , Article Review)
Colorectal cancer (CRC), the third most common type of cancer, is the second leading cause of cancer-related mortality rates worldwide. Although modern research was able to shed light on the pathogenesis of CRC and provide ...
The Interplay Between Diet and the Epigenome in the Pathogenesis of Type-1 Diabetes
(
Frontiers
, 2021 , Article Review)
The autoimmune disease, Type 1 Diabetes Mellitus (T1DM), results in the destruction of pancreatic β-cells, and the International Diabetes Federation reports that its incidence is increasing worldwide. T1DM is a complex ...
Protocols for meta-analysis of intervention safety seldom specified methods to deal with rare events
(
Elsevier
, 2020 , Article Review)
ObjectivesMeta-analyses of rare events often generate unstable results, and selective reporting of the results may mislead the health care decision. Developing a synthesis plan for rare events in protocol may help to ...
Balancing the benefits from the water–energy–land–food nexus through agroforestry in the Sahel
(
Elsevier
, 2020 , Article Review)
Regions affected by resource scarcity, poverty, and land-use conflicts need to advocate the merits of practices strongly grounded in sustainable land management. This review paper provides an analysis of agroforestry as ...
Information, Thermodynamics and Life: A Narrative Review
(
MDPI
, 2021 , Article Review)
Information is probably one of the most difficult physical quantities to comprehend. This applies not only to the very definition of information, but also to the physical entity of information, meaning how can it be ...
An overview of brine management: Emerging desalination technologies, life cycle assessment, and metal recovery methodologies
(
Elsevier
, 2021 , Article Review)
This study examines which management methods are the most recent and advanced in managing rejected brine generated from desalination plants. It also provides up-to-date information regarding the most adequate technologies ...