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Effect of recombinant human erythropoietin and doxorubicin in combination on the proliferation of MCF-7 and MDA-MB231 breast cancer cells
(
Spandidos Publications
, 2016 , Article)
Patients with cancer often exhibit signs of anemia as the result of the disease. Thus, cancer chemotherapies often include erythropoietin (EPO) in the regime to improve the survival rate of these patients. The aim of the ...
A Critical Review of the Current Evidence for Measuring Drug Concentrations of First-Line Agents Used to Treat Tuberculosis in Children
(
Springer International Publishing
, 2016 , Article Review)
Tuberculosis is a leading cause of infectious disease-related morbidity and mortality worldwide. Additionally, treatment is complex with most patients requiring combination therapy of first-line agents for multiple months. ...
Glucocorticoid-induced fetal origins of adult hypertension: Association with epigenetic events
(
Elsevier Inc.
, 2016 , Article Review)
Hypertension is a predominant risk factor for cardiovascular diseases and a major health care burden. Accumulating epidemiological and experimental evidence suggest that adult-onset hypertension may have its origins during ...
Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors
(
Elsevier Masson SAS
, 2016 , Article)
A novel series of substituted chalcones were designed and synthesized to be evaluated as selective human MAO-B inhibitors. A combination of either methylsulfonyl or trifluoromethyl substituents on the aromatic ketone moiety ...
Glycoside-based niosomal nanocarrier for enhanced in-vivo performance of Cefixime
(
Elsevier B.V.
, 2016 , Article)
This study aimed to evaluate the potential of a novel glycoside non-ionic surfactant synthesized and characterized in our laboratory for increased oral bioavailability of Cefixime. The surfactant was synthesized by simple ...
Identification of SER-PRO-CYS Peptide in Blood Serum of Multiple Sclerosis Patients
(
Bentham Science Publishers
, 2016 , Article)
Monitoring of multiple sclerosis (MS) requires additional molecular markers. Recently, we used original TCA-precipitation/extraction approach in combination with MALDI TOF/TOF mass-spectrometry and identified earlier unknown ...