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Silybin as a potent inhibitor of a-synuclein aggregation and associated cytotoxicity against neuroblastoma cells induced by zinc oxide nanoparticles
(
Elsevier B.V.
, 2020 , Article)
a-synuclein (a-syn) amyloid fibrils, the leading neurotoxic types, are predominately formed through interaction with nanoparticles (NPs). However, some natural compounds like silybin can reduce the formation of NPs-induced ...
Cerium oxide NPs mitigate the amyloid formation of α-synuclein and associated cytotoxicity
(
Dove Medical Press Ltd.
, 2019 , Article)
Aim: Among therapeutic proposals for amyloid-associated disorders, special attention has been given to the exploitation of nanoparticles (NPs) as promising agents against aggregation. Methods: In this paper, the inhibitory ...
Albumin binding, antioxidant and antibacterial effects of cerium oxide nanoparticles
(
Elsevier B.V.
, 2019 , Article)
Herein, the interaction of CeO2 NPs with HSA was explored by fluorescence, CD, UV–vis and molecular docking studies. Afterwards, the antioxidant activity of CeO2 NPs against H2O2-induced oxidative stress in BM-MSCs were ...
Exploring the interaction of cobalt oxide nanoparticles with Albumin, leukemia cancer cells and pathogenic bacterial by multispectroscopic, docking, cellular and antibacterial approaches
(
Dove Medical Press Ltd.
, 2020 , Article)
Aim: The interaction of NPs with biological systems may reveal useful details about their pharmacodynamic, anticancer and antibacterial effects. Methods: Herein, the interaction of as-synthesized Co3O4 NPs with HSA was ...