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Glycoprofiling as a novel tool in serological assays of systemic sclerosis: A comparative study with three bioanalytical methods
(
Elsevier
, 2015 , Article)
Systemic sclerosis (SSc) is an autoimmune disease seriously affecting patient’s quality of life. The heterogeneity of the disease also means that identification and subsequent validation of biomarkers of the disease is ...
Highly stable Ti3C2Tx (MXene)/Pt nanoparticles-modified glassy carbon electrode for H2O2 and small molecules sensing applications
(
Elsevier B.V.
, 2018 , Article)
© 2018 Elsevier B.V. Electrochemical performance of a 2D Ti3C2Tx (MXene, where T: [dbnd]O, –OH, –F) sheets modified with Pt nanoparticles (PtNPs) was investigated. The results showed that Ti3C2Tx/PtNP nanocomposite deposited ...
Glycomics of prostate cancer: updates
(
Taylor and Francis Ltd
, 2019 , Article)
Introduction: Prostate cancer (PCa) is a life-threatening disease affecting millions of men. The current best PCa biomarker (level of prostate-specific antigen in serum) lacks specificity for PCa diagnostics and this is ...
Anisotropy in CNT composite fabricated by combining directional freezing and gamma irradiation of acrylic acid
(
Elsevier, Ltd
, 2016 , Article)
A novel fabrication process for composite consisting of organized modified carbon nanotubes (CNT) in the polyacrylic acid (PAA) matrix has been developed. The CNT were organized along crystallite domains during a directional ...
PH-Switchable Interaction of a Carboxybetaine Ester-Based SAM with DNA and Gold Nanoparticles
(
American Chemical Society
, 2017 , Article)
We describe a self-assembled monolayer (SAM) on a gold surface with a carboxybetaine ester functionality to control the interaction between DNA and gold nanoparticles via pH. The negatively charged phosphate backbone of ...
Mixed Zwitterion-Based Self-Assembled Monolayer Interface for Impedimetric Glycomic Analyses of Human IgG Samples in an Array Format
(
American Chemical Society
, 2016 , Article)
An impedimetric lectin biosensor for the detection of changes in the glycan structure of antibodies isolated from human serum is here correlated with the progression of rheumatoid arthritis (RA). The biosensor was built ...
Simple, Reversible, and Fast Modulation in Superwettability, Gradient, and Adsorption by Counterion Exchange on Self-Assembled Monolayer
(
American Chemical Society
, 2016 , Article)
A simple fabrication method for preparation of surfaces able to switch from superhydrophobic to superhydrophilic state in a reversible and fast way is described. A self-assembled monolayer (SAM) consisting of quaternary ...
Immobilization of bilirubin oxidase on graphene oxide flakes with different negative charge density for oxygen reduction. The effect of GO charge density on enzyme coverage, electron transfer rate and current density
(
Elsevier Ltd
, 2017 , Article)
Previously we showed that an effective bilirubin oxidase (BOD)-based biocathode using graphene oxide (GO) could be prepared in 2 steps: 1. electrostatic adsorption of BOD on GO; 2. electrochemical reduction of the BOD-GO ...
Electrochemical performance of Ti3C2Tx MXene in aqueous media: towards ultrasensitive H2O2 sensing
(
Elsevier Ltd
, 2017 , Article)
An extensive characterization of pristine and oxidized Ti3C2Tx (T: O, OH, F) MXene showed that exposure of MXene to an anodic potential in the aqueous solution oxidizes the nanomaterial forming TiO2 layer or TiO2 domains ...
Immobilization of concanavalin A lectin on a reduced graphene oxide-thionine surface by glutaraldehyde crosslinking for the construction of an impedimetric biosensor
(
Elsevier B.V.
, 2017 , Article)
Lectins, which are proteins with selective affinity to glycans or glycoproteins, have been recognized as promising agents for the construction of devices for the detection of specific glycoproteins and for glycoprofiling. ...