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Molecular profiling of the metaplastic spindle cell carcinoma of the breast reveals potentially targetable biomarkers
(
Elsevier
, 2020 , Article)
IntroductionSpindle cell carcinoma is a rare subtype of metaplastic breast cancer (MBC), with triple-negative (TNBC: ER-/PR-/Her2-) phenotype. It is associated with a marked resistance to conventional chemotherapy and has ...
Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
(
Elsevier
, 2021 , Article)
HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. It is characterized by aggressive behavior and treatment resistance. On the other hand, poly (amidoamine) (PAMAM) ...
The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach
(
Elsevier
, 2020 , Article)
Breast cancer (BC) is one of the leading causes of cancer-related death among women worldwide, and claudin-low breast cancer (CLBC) is a subtype of BC that remains poorly described. This study aimed to identify upregulated ...
High-risk human papillomaviruses and Epstein-Barr virus in breast cancer in Lebanese women and their association with tumor grade: a molecular and tissue microarray study.
(
BMC
, 2021 , Article)
High-risk human papillomaviruses (HPVs) are present and can cooperate with Epstein-Barr virus (EBV) to initiate and/or enhance the progression of several types of human carcinomas including cervical as well as head and ...
Molecular Evidence of Anticancer Activity of Camel Milk Combined with Camel Urine
(
Austin Publishing Group
, 2021 , Article)
Camel Milk (CM) and Camel Urine (CU) is a traditional practice in the
Middle East and other countries as an alternative treatment against cancer. We
hypothesized that a combination of CM and CU (CM+CU), used at ...
Cost-effectiveness analyses of breast cancer medications use in developing countries: a systematic review
(
Taylor and Francis Ltd.
, 2020 , Article)
Background: Pharmacoeconomics is important for breast-cancer medications due to their high costs. To our knowledge, no systematic literature reviews of pharmacoeconomic studies for breast-cancer medication use are present ...
3D bioprinting of engineered breast cancer constructs for personalized and targeted cancer therapy
(
Elsevier B.V.
, 2021 , Article)
The bioprinting technique with specialized tissue production allows the study of biological, physiological, and behavioral changes of cancerous and non-cancerous tissues in response to pharmacological compounds in personalized ...
Development of point-of-care nanobiosensors for breast cancers diagnosis
(
Elsevier B.V.
, 2020 , Article)
Nanobiosensors have played a key role as portable devices in the rapid breast cancer diagnosis and in clinical medicine like point-of-care devices. However, understanding biomarkers and nanomaterials is crucial for improving ...
Diagnostic and drug release systems based on microneedle arrays in breast cancer therapy
(
Elsevier B.V.
, 2021 , Article)
Microneedle arrays have recently received much attention as cancer detection and treatment platforms, because invasive injections and detection of the biopsy are not needed, and drug metabolism by the liver, as well as ...
Acinic cell carcinoma of the breast: A comprehensive review
(
Elsevier
, 2022 , Article)
Acinic cell carcinoma of the breast is a rare special subtype of breast cancer in the category of salivary gland-type tumors. It is morphologically similar to acinic cell carcinomas of salivary glands and pancreas and has ...