تصفح Medicine Research حسب العنوان

السجلات المعروضة 527 -- 546 من 1337

    • The Exposure to Human Breast Cancer Cells Altered 14 Post-Translational Modifications of Human Serum Albumin. 

      Kannan, Surya; Souchelnytskyi, Serhiy ( International Federation of Clinical Chemistry and Laboratory Medicine , 2022 , Article)
      Serum albumin is in contact with practically all cells in the human body, including tumor cells in cancer patients. The purpose of this study was to explore whether cancer cells affect post-translational modifications ...

    • Expression and subcellular localization of Discoidin Domain Receptor 1 (DDR1) define prostate cancer aggressiveness 

      Bonfil, R. Daniel; Chen, Wei; Vranic, Semir; Sohail, Anjum; Shi, Dongping; ... more authors ( BMC , 2021 , Article)
      Background: The Discoidin Domain Receptor 1 (DDR1) is one of the two members of a unique family of receptor tyrosine kinase receptors that signal in response to collagen, which has been implicated in cancer progression. ...

    • Expression of sperm PLC? and clinical outcomes of ICSI-AOA in men affected by globozoospermia due to DPY19L2 deletion 

      Tavalaee M.; Nomikos M.; Lai F.A.; Nasr-Esfahani M.H. ( Elsevier Ltd , 2018 , Article)
      Globozoospermia is characterized by the presence of 100% acrosomeless round-headed spermatozoa in an ejaculate. Failed fertilization after intracytoplasmic sperm injection (ICSI) is commonly reported for globozoospermic ...

    • External Validation and Recalibration of the CURB-65 and PSI for Predicting 30-Day Mortality and Critical Care Intervention in Multiethnic Patients with COVID-19 

      Elmoheen, Amr; Abdelhafez, Ibrahim; Salem, Waleed; Bahgat, Mohamed; Elkandow, Ali; ... more authors ( Elsevier , 2021 , Article)
      Objectives: To validate and recalibrate the CURB-65 and pneumonia severity index (PSI) in predicting 30-day mortality and critical care intervention (CCI) in a multiethnic population with COVID-19, along with evaluating ...

    • Extremity Ischemia After Jellyfish Envenomation: A Case Report and Systematic Review of the Literature 

      Saif, Badran; Eldos, Yazeed; Hoffman, Robert J.; Obaray, Sabeena; Sivakumar, Bran; ... more authors ( Elsevier , 2022 , Article)
      BackgroundExtremity ischemia and necrosis after jellyfish envenomation can be mutilating and cause long-term functional deficits. The best way to manage these presentations is unknown. ObjectiveThe aim of this review was ...

    • F-box proteins in cancer stemness: An emerging prognostic and therapeutic target 

      Abdul Q., Khan; Al-Tamimi, Maha; Uddin, Shahab; Steinhoff, Martin ( Elsevier , 2021 , Article)
      Cancer is a complex heterogenic disease with significant therapeutic challenges. The presence of cancer stem cells (CSCs) in cancer tissue orchestrates tumor growth, progression, and metastasis, the tumor heterogeneity, ...

    • Facial Nerve Palsy in Hypertriglyceridemia-Induced Pancreatitis: A Case Report and Literature Review. 

      Khalil, Sondos K; Khalil, Sulafa K; Al Refai, Fakhreddin; B Yousif, Zahra; Maliyakkal, Abdul Majeed; ... more authors ( Springer , 2023 , Article)
      Acute pancreatitis is associated with multiple local or systemic complications in response to systemic inflammation that may eventually result in multi-organ failure. Neurological complications are uncommon in acute ...

    • Factors associated with depression and anxiety in the adult population of Qatar after the first COVID-19 wave: a cross-sectional study 

      Khaled, Salma Mawfek; Amro, Iman; Bader, Lina; Woodruff, Peter; Alabdulla, Majid A.; ... more authors ( springer , 2021 , Article)
      There is limited data from Arabic-speaking countries on risk factors for depression and anxiety during the COVID-19 pandemic. Country-specific data is necessary given differences in culture, demographics, and COVID-19 ...

    • Failed immune responses across multiple pathologies share pan-tumor and circulating lymphocytic targets 

      Monette, Anne; Morou, Antigoni; Al-Banna, Nadia A.; Rousseau, Louise; Lattouf, Jean-Baptiste; ... more authors ( American Society for Clinical Investigation , 2019 , Article)
      Tumor-infiltrating lymphocytes (TILs) are widely associated with positive outcomes, yet carry key indicators of a systemic failed immune response against unresolved cancer. Cancer immunotherapies can reverse their tolerance ...

    • Fascin in Gynecological Cancers: An Update of the Literature 

      Gupta, Ishita; Vranic, Semir; Al-Thawadi, Hamda; Al Moustafa, Ala-Eddin ( MDPI , 2021 , Article)
      Fascin is an actin-binding protein that is encoded by the gene (located on chromosome 7). It triggers membrane projections and stimulates cell motility in cancer cells. Fascin overexpression has been described in different ...

    • Fatty acid-binding protein 5 (FABP5)-related signal transduction pathway in castration-resistant prostate cancer cells: a potential therapeutic target 

      Naeem, Abdulghani A.; Abdulsamad, Saud A.; Rudland, Philip S.; Malki, Mohammed I.; Ke, Youqiang ( Oxford University Press , 2019 , Article Review)
      In this short communication, a novel fatty acid-binding protein 5 (FABP5)-related signal transduction pathway in prostate cancer is reviewed. In castration-resistant prostate cancer (CRPC) cells, the FABP5-related signal ...

    • Fetal ECG extraction from maternal ECG using deeply supervised LinkNet++ model 

      Arafat, Rahman; Mahmud, Sakib; Chowdhury, Muhammad E.H.; Yalcin, Huseyin Cagatay; Khandakar, Amith; ... more authors ( Elsevier , 2023 , Article)
      Fetal heart monitoring and early disease detection using non-invasive fetal electrocardiograms (fECG) can help substantially to reduce infant death through improved diagnosis of Coronary Heart Disease (CHD) in the fetus. ...

    • Fetal holoprosencephaly 

      Al-Khawaja, Fatima; Madut, Mary J.; Abdo, Gamal; Noor, Helmi; Ahmed, Badreldeen ( Jaypee Brothers Medical Publishers (P) Ltd , 2020 , Article)
      Holoprosencephaly is a birth defect that leads to an abnormal brain development where the brain fails to divide into two hemispheres. Possible causes are environmental or genetic factors. Holoprosencephaly can include ...

    • Fetal lung maturity assessment: A historic perspective and Non – invasive assessment using an automatic quantitative ultrasound analysis (a potentially useful clinical tool) 

      Ahmed, Badreldeen; Konje, Justin C. ( Elsevier , 2021 , Article)
      Immature fetal lung is associated with many adverse outcomes including respiratory distress syndrome and transient tachypnoea of the newborn. Several methods/tools have been used over several decades to assess fetal lung ...

    • Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity 

      Gupta, Vijay; Salim, Safa; Hmila, Issam; Vaikath, Nishant N.; Sudhakaran, Indulekha P.; ... more authors ( Springer Nature , 2020 , Article)
      Synucleinopathies including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA) are characterized by pathological accumulation of α-synuclein (α-syn). Amongst the various approaches ...

    • First sliding Amyand hernia harbouring appendicular schistosomiasis: Case report 

      Toffaha, Ali; El Ansari, Walid; Elaiwy, Orwa; Obaid, Munzir; Al-Yahri, Omer; ... more authors ( Elsevier Ltd , 2019 , Article)
      Introduction: Amyand's hernia (AH) is rare, schistosomiasis of the appendix is very uncommon, and both conditions coexisting together is an extremely rare event. Pre-operative diagnosis of each of the two conditions is ...

    • Five insights from the Global Burden of Disease Study 2019 

      Christopher J L, Murray; Abbafati, Cristiana; Abbas, Kaja M; Abbasi, Mohammad; Abbasi-Kangevari, Mohsen; ... more authors ( Elsevier , 2020 , Article Review)
      The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system ...

    • Flight Versus Ground Out-of-hospital Rapid Sequence Intubation Success: a Systematic Review and Meta-analysis 

      Fouche, P.F.; Stein, C.; Simpson, P.; Carlson, J.N.; Zverinova, K.M.; ... more authors ( Taylor and Francis Ltd , 2018 , Article)
      Introduction: Endotracheal intubation (ETI) is a critical procedure performed by both air medical and ground based emergency medical services (EMS). Previous work has suggested that ETI success rates are greater for air ...

    • Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents 

      Ayoub, Abeer J.; El-Achkar, Ghewa A.; Ghayad, Sandra E.; Hariss, Layal; Haidar, Razan H.; ... more authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)
      Benzofuran and 2,3-dihydrobenzofuran scaffolds are heterocycles of high value in medicinal chemistry and drug synthesis. Targeting inflammation in cancer associated with chronic inflammation is a promising therapy. In the ...

    • Follicular dendritic cells 

      Abd El-Aleem, Seham A; Saber, Entesar Ali; Aziz, Neven M; El-Sherif, Hani; Abdelraof, Asmaa M; ... more authors ( Wiley , 2021 , Article Review)
      Follicular dendritic cells (FDCs) are unique accessory immune cells that contribute to the regulation of humoral immunity. They are multitasker cells essential for the organization and maintenance of the lymphoid architecture, ...