تصفح Medicine Research حسب العنوان
السجلات المعروضة 850 -- 869 من 1320
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Nanoparticles: Attractive tools to treat colorectal cancer
( Elsevier , 2022 , Article)Colorectal Cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Despite the notable advances achieved over the last few decades, CRC remains a hard-to-treat deadly disease in many patients. This ... -
Nanotoxicology of dendrimers in the mammalian heart: Ex vivo and in vivo administration of g6 pamam nanoparticles impairs recovery of cardiac function following ischemia-reperfusion injury
( Dove Medical Press Ltd. , 2020 , Article)Aim: The effects of polyamidoamine (PAMAM) dendrimers on the mammalian heart are not completely understood. In this study, we have investigated the effects of a sixth-generation cationic dendrimer (G6 PAMAM) on cardiac ... -
Naturally-Occurring Bioactives in Oral Cancer: Preclinical and Clinical Studies, Bottlenecks and Future Directions
( IMR Press Limited , 2022 , Article)Oral cancer (OC) is the eighth most common cancer, particularly prevalent in developing countries. Current treatment includes a multidisciplinary approach, involving chemo, radio, and immunotherapy and surgery, which depends ... -
NDDNet: a deep learning model for predicting neurodegenerative diseases from gait pattern
( Springer Nature , 2023 , Article)Neurodegenerative diseases damage neuromuscular tissues and deteriorate motor neurons which affects the motor capacity of the patient. Particularly the walking gait is greatly influenced by the deterioration process. Early ... -
Neisseria gonorrhoeae Ketol-Acid Reductoisomerase Is a Potential Therapeutic Target
( IntechOpen , 2022 , Book chapter)The host-adapted human pathogen Neisseria gonorrhoeae is the causative agent of sexually transmitted infection gonorrhea. The increased emergence of gonorrhea infections worldwide, associated with the surging resistance ... -
The Net Clinical Benefit of Rivaroxaban Compared to Low-Molecular-Weight Heparin in the Treatment of Cancer-Associated Thrombosis: Systematic Review and Meta-Analysis
( SAGE , 2021 , Article)Cancer-associated thrombosis (CAT) carries significant morbidity and mortality. Low-molecular-weight heparin (LMWH) remains the standard of care, with recent systematic studies suggesting the efficacy and safety of rivaroxaban ... -
Network analysis of anxiety and depressive symptoms among quarantined individuals: Cross-sectional study
( Cambridge University Press , 2021 , Article)Background The mental health burden of COVID-19 has been examined in different settings. Existing research has relied on the latent variable model in assessing COVID-19-related distress. Network theory provides an alternative ... -
Neurological Complications of Local Anesthesia in Dentistry: A Review.
( Springer Nature , 2023 , Article)Local anesthesia is a technique that temporarily desensitizes a specific body area, typically for a surgical procedure, dental work, or pain management. It is described as a sensation loss in a specific area of the body ... -
Neuronal Cell Types in the Anterior Ventral Thalamic Nucleus of the Camel.
( Wiley , 2021 , Article)The anterior ventral nucleus neurons in of the camel brain were morphologically studied by Golgi impregnation method. Two neuronal types of were found in the camel anterior ventral thalamic nucleus, namely, Golgi-type I ... -
Neuronal Cell Types in the Spinal Trigeminal Nucleus of the Camel Brain.
( MDPI , 2023 , Article)Neurons in the spinal trigeminal nucleus of a camel were morphologically studied by the Golgi impregnation method. The neurons were classified based on the size and shape of their cell bodies, the density of their dendritic ... -
Neuropathic itch
( NLM (Medline) , 2019 , Article)Neuropathic itch is clinically important but has received much less attention as compared to neuropathic pain. In the past decade, itch-specific pathways have been characterized on a cellular and molecular level, but their ... -
Neurotrauma investigation through spatial omics guided by mass spectrometry imaging: Target identification and clinical applications
( Wiley , 2023 , Article Review)Traumatic brain injury (TBI) represents one of the major public health concerns worldwide due to the increase in TBI incidence as a result of injuries from daily life accidents such as sports and motor vehicle transportation ... -
Neutralizing antibodies against SARS-CoV-2 are higher but decline faster in mRNA vaccinees compared to individuals with natural infection.
( Oxford University Press , 2022 , Article)Waning protection against emerging SARS-CoV-2 variants by pre-existing antibodies elicited due to current vaccination or natural infection is a global concern. Whether this is due to the waning of immunity to SARS-COV-2 ... -
New clinical approaches and emerging evidence on immune-checkpoint inhibitors as anti-cancer therapeutics: CTLA-4 and PD-1 pathways and beyond
( Begell House Inc. , 2019 , Article)The development of immune checkpoint blockers, primarily comprising the anti-PD-1/anti-PD-L1 and anti-CTLA-4 monoclonal antibodies, has formed the therapeutic landscape of quite a few different cancer types. In spite of ... -
A new improved graphical and quantitative method for detecting bias in meta-analysis.
( Lippincott, Williams & Wilkins , 2018 , Article)Detection of publication and related biases remains suboptimal and threatens the validity and interpretation of meta-analytical findings. When bias is present, it usually differentially affects small and large studies ... -
New insight into the role of PTCH1 protein in serous ovarian carcinomas.
( Spandidos Publications , 2022 , Article)The Hedgehog (Hh) signaling pathway is essential for normal embryonic development, while its hyperactivation in the adult organism is associated with the development of various cancers. The role of the Hh signaling pathway ... -
A new method for synthesizing test accuracy data outperformed the bivariate method
( Elsevier , 2020 , Article)This paper outlines the development of a new method (split component synthesis; SCS) for meta-analysis of diagnostic accuracy studies and assesses its performance against the commonly used bivariate random effects model. ... -
Nicolau syndrome following Intramuscular Diclofenac Injection: a case report and review of the literature.
( Oxford University Press , 2023 , Article)Nicolau syndrome (NS), also referred as embolia cutis medicamentosa and livedo-like dermatitis, is an uncommon complication followed by drugs administered intramuscularly, intraarticularly or subcutaneously. In this case ... -
No Association Between Ct Value and COVID-19 Severity and Mortality in Qatar.
( Dove Press Ltd , 2023 , Article)The association between the cycle threshold (Ct) which reflects the SARS-CoV-2 viral load and the severity of COVID-19 is still not clear. We investigated the association between Ct values, symptoms and the risk of ICU ... -
Nociceptor subtypes and their incidence in rat lumbar dorsal root ganglia (DRGs): focussing on C-polymodal nociceptors, A?-nociceptors, moderate pressure receptors and their receptive field depths
( Elsevier Ltd , 2019 , Article Review)A recent study with Ca++-sensitive-dyes in neurons in whole DRGs (Table 5) found that much lower percentages of nociceptors were polymodal-nociceptors (PMNs) (Emery et al., 2016), than the 50–80% values in many ...