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Now showing items 1431-1440 of 1443
Optimal dilation time for combined small endoscopic sphincterotomy and balloon dilation for common bile duct stones: a multicentre, single-blinded, randomised controlled trial
(
Elsevier Ltd
, 2019 , Article)
Background
Endoscopic sphincterotomy is the established treatment for common bile duct stones. Balloon dilation offers an alternative. Prolonged dilation (300 s) with a 10 mm diameter balloon decreases the occurrence of ...
Evaluation of community pharmacists' preparedness for the provision of cardiovascular disease risk assessment and management services: A study with simulated patients
(
Elsevier Inc.
, 2019 , Article)
Background
Individuals who suffer from major cardiovascular events every year have one or more risk factors. Cardiovascular disease (CVD) risk assessment is an important strategy for the early identification of modifiable ...
Evaluations of Morphine and Fentanyl for Mechanically Ventilated Patients With Respiratory Disorders in Intensive Care: A Systematic Review of Methodological Trends and Reporting Quality
(
Elsevier Inc.
, 2019 , Article)
Background: Mechanically ventilated patients with respiratory disorders may require sedatives, such as opioids. Objectives: To define methodological trends, gaps, and the reporting quality of the comparative clinical and ...
Impact of a Collaborative Pharmaceutical Care Service Among Patients With Diabetes in an Ambulatory Care Setting in Qatar: A Multiple Time Series Study
(
Elsevier Inc.
, 2019 , Article)
Background
Diabetes mellitus is highly prevalent in the Middle East and the burden associated with it is dramatically increasing. Pharmacists working in collaborative healthcare teams have an important role to improve ...
A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase
(
Elsevier
, 2019 , Article)
DNA repair mechanism is a process through which the cell repairs its damaged DNA. Although there are several mechanisms involved in the DNA repair mechanisms, the direct reversal method is the simplest and does not require ...
Patient-dentist relationship and dental anxiety among young Sudanese adult patients
(
Elsevier
, 2019 , Article)
Objective: To evaluate the effects of the patient–dentist relationship on dental anxiety among young adult Sudanese patients. Materials and methods: In this cross-sectional study, 864 patients attending outpatient dental ...
P-value driven methods were underpowered to detect publication bias: analysis of Cochrane review meta-analyses
(
Elsevier
, 2019 , Article)
To investigate the effect of number of studies in a meta-analysis on the detection of publication bias using p-value driven methods. The proportion of meta-analyses detected by Egger's, Harbord's, Peters', and Begg's tests ...
PD-L1 status in breast cancer: Current view and perspectives.
(
Elsevier
, 2019 , Article)
Breast cancer was traditionally not considered a particularly immunogenic tumor. However, recent developments have shown that some aggressive triple-negative breast cancers are immunogenic, exhibit a resistance to chemotherapy ...
Impact of a Collaborative Pharmaceutical Care Service Among Patients With Diabetes in an Ambulatory Care Setting in Qatar: A Multiple Time Series Study
(
Elsevier
, 2019 , Article)
Background
Diabetes mellitus is highly prevalent in the Middle East and the burden associated with it is dramatically increasing. Pharmacists working in collaborative healthcare teams have an important role to improve ...
Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity
(
Elsevier
, 2019 , Article)
The study of rare families with inherited pain insensitivity can identify new human-validated analgesic drug targets. Here, a 66-yr-old female presented with nil requirement for postoperative analgesia after a normally ...