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Targeting SARS-CoV2 Spike Protein Receptor Binding Domain by Therapeutic Antibodies
(
Elsevier
, 2020 , Article)
The Authors As the number of people infected with the newly identified 2019 novel coronavirus (SARS-CoV2) is continuously increasing every day, development of potential therapeutic platforms is vital. Based on the comparatively ...
Introduction to Tissue Engineering
(
Wiley-VCH Verlag
, 2016 , Article)
Tissue engineering is a recent field that aims at developing or regenerating artificial tissues and organs. The idea of replacing a damaged body part using materials from natural origin was proposed and even applied over ...
Natural halloysite nanotubes /chitosan based bio-nanocomposite for delivering norfloxacin, an anti-microbial agent in sustained release manner
(
Elsevier B.V.
, 2020 , Article)
Applying nanotechnology to deliver drug could result in several benefits such as prolong duration of action, enhancement in overall bioavailability, targeting to specific site, low initial loading dose require, systemic ...
Enzyme?polymeric/inorganic metal oxide/hybrid nanoparticle bio-conjugates in the development of therapeutic and biosensing platforms
(
Elsevier B.V.
, 2021 , Article)
Background: Because enzymes can control several metabolic pathways and regulate the production of free radicals, their simultaneous use with nanoplatforms showing protective and combinational properties is of great interest ...
Nanozyme-based sensing platforms for detection of toxic mercury ions: An alternative approach to conventional methods
(
Elsevier B.V.
, 2020 , Article)
Mercury (Hg) is known as a poisonous heavy metal which stimulates a wide range of adverse effects on the human health. Therefore, development of some feasible, practical and highly sensitive platforms would be desirable ...
Exploring the interaction of synthesized nickel oxide nanoparticles through hydrothermal method with hemoglobin and lymphocytes: Bio-thermodynamic and cellular studies
(
Elsevier B.V.
, 2020 , Article)
The NiO NPs were synthesized by hydrothermal method and their interaction with Hb was investigated by employing fluorescence, UV?vis absorption techniques as well as docking studies. Also, the cytotoxic impacts of NiO NPs ...
Enzyme immobilization onto the nanomaterials: Application in enzyme stability and prodrug-activated cancer therapy
(
Elsevier B.V.
, 2020 , Article)
Nanoparticles (NPs) have been widely used for immobilization of wide ranges of enzymes. However, the stabilization of enzymes on NPs is a major challenge, crucial for regulating enzymatic activity and their medical ...
Modulation of proteomic and inflammatory signals by Bradykinin in podocytes
(
Elsevier B.V.
, 2020 , Article)
Podocyte damage is one of the hallmarks of diabetic nephropathy leading to proteinuria and kidney damage. The underlying mechanisms of podocyte injury are not well defined. Bradykinin (BK) was shown to contribute to diabetic ...
Antioxidant properties of gold nanozyme: A review
(
Elsevier B.V.
, 2020 , Article)
AuNPs with enzyme-like features have received strong attention in different areas, although limited data is available in literature on their biological/industrial functions. NPs especially Au counterparts have been shown ...
Gold nanozyme: Biosensing and therapeutic activities
(
Elsevier Ltd
, 2020 , Article)
The utilization of AuNPs in therapeutic applications has been accelerated by discovering their catalytic activity consistent with the activity of natural enzymes. However, to reduce unwanted activities, it is imperative ...