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Impact of phthalate metabolites on vitamin D levels and subclinical inflammation: national health and nutrition examination survey, 2013–2018
(
Taylor and Francis Ltd.
, 2024 , Article)
This study explores the association between phthalates and total vitamin D levels and the link between phthalates exposure and subclinical inflammation using monocyte percentage to high-density lipoprotein cholesterol ratio ...
Integrated health system intervention aimed at reducing type 2 diabetes risk in women after gestational diabetes in South Africa (IINDIAGO): A randomised controlled trial protocol
(
BMJ Publishing Group
, 2024 , Article)
Introduction South Africa has a high prevalence of gestational diabetes mellitus (GDM; 15%) and many of these women (48%) progress to type 2 diabetes mellitus (T2DM) within 5 years post partum. A significant proportion ...
Prenatal psychological distress and 11β-HSD2 gene expression in human placentas: Systematic review and meta-analysis
(
Elsevier
, 2024 , Article Review)
BackgroundThe placenta acts as a buffer to regulate the degree of fetal exposure to maternal cortisol through the 11-Beta Hydroxysteroid Dehydrogenase isoenzyme type 2 (11-β HSD2) enzyme. We conducted a systematic review ...
A combined strategies intervention on the World Health Organization prescribing indicators: A quasi-randomised trial.
(
AOSIS Publishing
, 2024 , Article)
Irrational medicine use is a global problem that may potentiate antimicrobial resistance. This study aims to assess prescribing practices and the effect of a prescription audit and feedback coupled with small-group education ...
Comparison of postoperative pain in children after maintenance anaesthesia with propofol or sevoflurane: a systematic review and meta-analysis.
(
Elsevier
, 2024 , Article Review)
Propofol and sevoflurane are two of the most commonly used anaesthetics for paediatric surgery. Data from some clinical trials suggest that postoperative pain incidence is lower when propofol is used for maintenance of ...
Is medical training solely to blame? Generational influences on the mental health of our medical trainees
(
Taylor & Francis
, 2024 , Article)
Introduction: The negative impact of medical training on trainee mental health continues to be a concern. Situated within a sociocultural milieu, Generation Z and Generation Y, defined by their highly involved parents and ...