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Dasatinib and PD-L1 inhibitors provoke toxicity and inhibit angiogenesis in the embryo
(
Elsevier
, 2021 , Article)
Dasatinib is a targeted cancer therapy, while programmed death ligand 1 (PD-L1) inhibitors are a form of immune checkpoint therapy used to treat various types of cancers. Several studies showed the potential efficacy of ...
Naked Poly(amidoamine) Dendrimer Nanoparticles Exhibit Intrinsic Embryotoxicity During the Early Stages of Normal Development.
(
American Science Publishers ASP
, 2020 , Article)
To investigate the impact of poly(amidoamine) dendrimers (PAMAMs) in the embryo, we explored the outcome of different generations (G₄ and G) on the early stages of embryogenesis using the chicken embryo as a model. We also ...
Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis
(
Elsevier
, 2021 , Article)
ObjectivesCytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our objective was to perform a living systematic ...
MXene Nanosheets May Induce Toxic Effect on the Early Stage of Embryogenesis.
(
American Scientific Publishers
, 2020 , Article)
MXene (Ti₃C₂T), as a novel 2D material, has produced a great interest due to its promising properties in biomedical applications, nevertheless, there is a lack of studies dedicated to investigate the possible toxic effect ...
Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential
(
Elsevier
, 2021 , Article)
Drug delivery systems or vectors are usually needed to improve the bioavailability and effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an organ, tissue or cellular level. However, emerging ...
Screening the growth inhibition mechanism of sulfate reducing bacteria by chitosan/lignosulfonate nanocomposite (CS@LS) in seawater media
(
Elsevier
, 2021 , Article)
Sulfate-reducing bacteria (SRBs) induced biofilm formation is a global industrial concern due to its role in the development of microbial-induced corrosion (MIC). Herein, we have developed a biodegradable chitosan/lignosulfonate ...
Heavy metal ions removal from industrial wastewater using magnetic nanoparticles (MNP)
(
Elsevier B.V.
, 2020 , Article)
A novel iron oxide magnetic nanoparticles (MNPs) grafted on hyperbranched polyglycerol (HPG) polymer were synthesized, characterized and tested for heavy metals (Ni, Cu and AL) removals from secondary effluent industrial ...
Decontamination of toxic Malathion pesticide in aqueous solutions by Fenton-based processes: Degradation pathway, toxicity assessment and health risk assessment
(
Elsevier B.V.
, 2022 , Article)
This study evaluates the degradation efficiency of Malathion using Fenton (Fe2+/H2O2: F), photo-Fenton (UV/Fe2+/H2O2: PF), and sono-photo Fenton (US/UV/Fe2+/H2O2: SPF) processes as well as determines the toxicity of the ...
Nanozyme-based sensing platforms for detection of toxic mercury ions: An alternative approach to conventional methods
(
Elsevier B.V.
, 2020 , Article)
Mercury (Hg) is known as a poisonous heavy metal which stimulates a wide range of adverse effects on the human health. Therefore, development of some feasible, practical and highly sensitive platforms would be desirable ...
Mesoporous silica coated carbon nanofibers reduce embryotoxicity via ERK and JNK pathways
(
Elsevier Ltd
, 2021 , Article)
Carbon nanofibers (CNFs) have been implicated in biomedical applications, yet, they are still considered as a potential hazard. Conversely, mesoporous silica is a biocompatible compound that has been used in various ...