Browsing Pharmacy Research by Author "Alkilany, Alaaldin M."
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Can we use normal saline stored under stress conditions? A simulated prehospital emergency medical setting
Rachid, Ousama; Akkbik, Mohammed; Alkilany, Alaaldin M.; Makhlouf, Ahmed; Al Shaikh, Loua; Alinier, Guillaume... more authors ... less authors ( Elsevier Ltd , 2023 , Article)Background: Data on stability and suitability to use normal saline stored under stress conditions in ambulances is lacking. Objective: We aimed to study the impact of exposure to extreme temperature variations on normal ... -
Comprehensive evaluation of the pharmacological and toxicological effects of γ-valerolactone as compared to γ-hydroxybutyric acid: Insights from in vivo and in silico models
Arfè, Raffaella; Bilel, Sabrine; Tirri, Micaela; Corli, Giorgia; Bergamin, Eva; Serpelloni, Giovanni; Bassi, Marta; Borsari, Martina; Boccuto, Federica; Bernardi, Tatiana; Caruso, Lorenzo; Alkilany, Alaaldin M.; Rachid, Ousama; Botrè, Francesco; De-Giorgio, Fabio; Marti, Matteo... more authors ... less authors ( Elsevier , 2023 , Article)Γ-valerolactone (GVL), marketed online as “Tranquilli-G” and “excellent Valium”, is used as a legal substitute for γ-hydroxybutyric acid (GHB); however, until now, GVL has only been connected to one Drug-Facilitated Sexual ... -
Eutectics in Pharmacy Curriculum: A Simple Demonstration with Pharmaceutical Relevance
Daou, Anis; Arakkal, Shijimol M.; Alkilany, Alaaldin M. ( acs Publications , 2023 , Article)In chemistry, a eutectic mixture refers to a mixture of two or more components at which the lowest possible freezing point is observed. This phenomenon is covered in a wide range of curricula such as physics, chemistry, ... -
PLGA-Gold Nanocomposite: Preparation and Biomedical Applications
Alkilany, Alaaldin M.; Rachid, Ousama; Alkawareek, Mahmoud Y.; Billa, Nashiru; Daou, Anis; Murphy, Catherine J.... more authors ... less authors ( MDPI , 2022 , Article)A composite system consisting of both organic and inorganic nanoparticles is an approach to prepare a new material exhibiting “the best of both worlds”. In this review, we highlight the recent advances in the preparation ... -
Quality by Design Approach in Liposomal Formulations: Robust Product Development
Alshaer, Walhan; Nsairat, Hamdi; Lafi, Zainab; Hourani, Omar M.; Al-Kadash, Abdulfattah; Esawi, Ezaldeen; Alkilany, Alaaldin M.... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Nanomedicine is an emerging field with continuous growth and differentiation. Liposomal formulations are a major platform in nanomedicine, with more than fifteen FDA-approved liposomal products in the market. However, as ... -
Therapeutic outcomes and biodistribution of gold nanoparticles in collagen-induced arthritis animal model
Nehal E., Abdel-Hakem; Talaat, Roba M.; Samaka, Rehab M.; Bassyouniy, Iman H.; EL-Shahat, Mohamed; Alkawareek, Mahmoud Y.; Alkilany, Alaaldin M.... more authors ... less authors ( Elsevier , 2022 , Other)The role of gold nanoparticles (AuNPs) in the treatment of autoimmune diseases remains mysterious. Therefore, we investigated the effect of AuNPs on collagen-induced arthritis (CIA) and the impact of particle size on the ...