Browsing Pharmacy Research by Subject "Warfarin"
Now showing items 1-16 of 16
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Anticoagulation clinic drive-up service during COVID-19 pandemic in Qatar
( Springer , 2021 , Article)Coronavirus Disease 2019 (COVID-19) is a pandemic affecting many countries worldwide. Given the increasing incidence especially in elderly and individuals with comorbid conditions, it is advised by health authorities to ... -
Assessment of the attitude, awareness and practice of periprocedural warfarin management among health care professional in Qatar. A cross sectional survey
( Springer , 2020 , Article)It is estimated that 10–15% of oral anticoagulant (OAC) patients, would need to hold their OAC for scheduled surgery. Especially for warfarin, this process is complex and requires multi-layer risk assessment and decisions ... -
Cancer-Associated Venous Thromboembolism
( Springer Healthcare , 2016 , Article Review)Cancer patients are at high risk for venous thromboembolism (VTE) which is considered the second leading cause of death among this population. Both cancer and cancer treatment increase this risk. Since the risk of VTE is ... -
Comparative effectiveness and safety of direct oral anticoagulants compared to warfarin in morbidly obese patients with acute venous thromboembolism: systematic review and a meta-analysis
( Springer , 2021 , Article)Direct oral anticoagulant (DOAC) agents are becoming the anticoagulation strategy of choice. However, their use in the treatment of acute venous thromboembolism (VTE) in morbidly obese patients (bodyweight of > 120 kg or ... -
Effect of SAMe-TT2R2 score and genetic polymorphism on the quality of anticoagulation control in Qatari patients treated with warfarin.
( Springer Nature , 2020 , Article)There is no strong evidence on pharmacogenetics role on the quality of INR control after the initiation phase and on the maintenance of stable INR on the long term as measured by the time in therapeutic range (TTR). The ... -
Evaluation of pharmacist-based compared to doctor-based anticoagulation management in Qatar
( Blackwell Publishing Ltd , 2016 , Article)Rationale, aims and objectives For over 60 years, warfarin has been the mainstay anticoagulant used in the outpatient setting for the prevention and treatment of a wide variety of thromboembolic clinical conditions. ... -
Evaluation of warfarin management in primary health care centers in Qatar: A retrospective cross-sectional analysis of the national dataset
( Elsevier , 2024 , Article Review)Background: Warfarin management is associated with severe complications, highlighting the critical need to evaluate the quality of its administration. Objectives: To evaluate the quality of warfarin management for patients ... -
Genetic and non-genetic factors impact on inr normalization in preprocedural warfarin management
( Dove Medical Press , 2021 , Article)Background: Annually, 10% of warfarin patients will likely need to stop warfarin prior to elective surgery to achieve a baseline international normalization ratio (INR) level (INR ≤ 1.2) at the time of the procedure. This ... -
Genetic polymorphism effect on warfarin–rifampin interaction: A case report and review of literature
( Dove Medical Press , 2021 , Article)Warfarin–rifampin interaction has been reported since the 1970s. Due to rifampin’s strong induction of CYP2C9, most cases could not attain the target international normalized ratio (INR) despite warfarin dose escalation. ... -
Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region
( Springer International Publishing , 2017 , Article Review)Background Genetic polymorphisms are known to influence outcomes with phenytoin yet effects in the Middle East and North Africa region are poorly understood. Objectives The objective of this systematic review was to ... -
Impact of GGCX, STX1B and FPGS Polymorphisms on Warfarin Dose Requirements in European-Americans and Egyptians
( Blackwell Publishing Ltd , 2016 , Article)Genotype-based algorithms that include VKORC1 and CYP2C9 genotypes are less predictive of warfarin dose variability in Africans as opposed to Europeans. Polymorphisms in GGCX, FPGS, or STX1B are associated with warfarin ... -
Rifampin-warfarin interaction in a mitral valve replacement patient receiving rifampin for infective endocarditis: a case report
( SpringerOpen , 2016 , Article)Warfarin therapy is associated with many drug interactions that may cause a significant alteration in its anticoagulant effect. Rifampin is a widely used antimicrobial that has major interactions with several medications ... -
Telephone versus office-based management of warfarin: Impact on international normalized ratios and outcomes
( Springer-Verlag Tokyo , 2014 , Article)Studies have concluded that telephone-based management of warfarin is an effective alternative to in-office management. High rates of patient and physician satisfaction have been reported with telephone-based monitoring. ... -
The impact of genetic and non-genetic factors on warfarin dose prediction in MENA region: A systematic review
( Public Library of Science , 2016 , Article Review)Background Warfarin is the most commonly used oral anticoagulant for the treatment and prevention of thromboembolic disorders. Pharmacogenomics studies have shown that variants in CYP2C9 and VKORC1 genes are strongly and ... -
Trends in New 75% Oral Anticgulant Use in Qatar: A 5-Year Experience
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Introduction: Warfarin has been the cornerstone oral anticoagulant for more than 60 years. Direct oral anticoagulants (DOACs) have been introduced to the market since 2008. In Qatar, dabigatran was introduced in 2011 ... -
Trends in oral anticoagulant use in Qatar: a 5-year experience
( Springer New York LLC , 2017 , Article)In Qatar, dabigatran was introduced in 2011 followed by rivaroxaban in 2014. In this study, we aim to explore the trends in oral anticoagulant use in Qatar over the past 5 years and to what extent did DOACs replace warfarin. ...