Browsing Pharmacy Research by Subject "diabetes"
Now showing items 1-15 of 15
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A program for obese youth at-risk for diabetes in Qatar
( Hamad bin Khalifa University Press (HBKU Press) , 2015 , Article)Background: Obesity is an international public health problem well documented in Qatar among children and adolescents and contributes to diabetes, a disease already highly prevalent in the country. We describe an intervention ... -
Assessment of the antidiabetic potential of extract and novel phytoniosomes formulation of Tradescantia pallida leaves in the alloxan-induced diabetic mouse model
( Wiley , 2023 , Article)Diabetes inflicts health and economic burdens on communities and the present antidiabetic therapies have several drawbacks. Tradescantia pallida leaves have been used as a food colorant and food preservative; however, to ... -
Barriers to Diabetes Adherence (BDA): Translation and Cultural Adaptation of the Instrument into Arabic Context
( Elsevier , 2020 , Article)Objectives: Barriers to Diabetes Adherence (BDA) instrument is a measure developed in English to assess barriers to adherence in adolescents with type 1 diabetes (T1DM). The main objectives of the present study were to ... -
Crosstalk Between Oxidative Stress and Endoplasmic Reticulum (ER) Stress in Endothelial Dysfunction and Aberrant Angiogenesis Associated With Diabetes: A Focus on the Protective Roles of Heme Oxygenase (HO)-1
( Frontiers Media , 2019 , Article Review)Type-2 diabetes prevalence is continuing to rise worldwide due to physical inactivity and obesity epidemic. Diabetes and fluctuations of blood sugar are related to multiple micro- and macrovascular complications, that are ... -
CTLA4-Ig (abatacept): a promising investigational drug for use in type 1 diabetes.
( Taylor & Francis , 2020 , Article Review)Type 1 diabetes (T1D) is an autoimmune disease that results from the destruction of insulin-producing beta cells in the pancreas; it leads to the under or nonproduction of insulin. T1D is associated with numerous ... -
Endoplasmic Reticulum Stress: A Critical Molecular Driver of Endothelial Dysfunction and Cardiovascular Disturbances Associated with Diabetes.
( MDPI , 2019 , Article)Physical inactivity and sedentary lifestyle contribute to the widespread epidemic of obesity among both adults and children leading to rising cases of diabetes. Cardiovascular disease complications associated with obesity ... -
From an Apple to a Pear: Moving Fat around for Reversing Insulin Resistance.
( MDPI , 2022 , Article Review)Type 2 diabetes (T2D) is a chronic condition where the body is resistant to insulin, leading to an elevated blood glucose state. Obesity is a main factor leading to T2D. Many clinical studies, however, have described a ... -
Interplay between Endoplasmic Reticulum Stress and Large Extracellular Vesicles (Microparticles) in Endothelial Cell Dysfunction
( MDPI , 2020 , Article)Upon increased demand for protein synthesis, accumulation of misfolded and/or unfolded proteins within the endoplasmic reticulum (ER), a pro-survival response is activated termed unfolded protein response (UPR), aiming at ... -
Molecular Mechanisms Underpinning Microparticle-Mediated Cellular Injury in Cardiovascular Complications Associated with Diabetes.
( Hindawi , 2019 , Article)Microparticles (MPs) are small vesicles shed from the cytoplasmic membrane of healthy, activated, or apoptotic cells. MPs are very heterogeneous in size (100-1,000 nm), and they harbor proteins and surface antigens specific ... -
Obesity Paradox among Heart Failure with Reduced Ejection Fraction Patients: A Retrospective Cohort Study
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Background and Objectives: There is consensus on the negative effects of obesity on the development of heart failure. However, several studies have suggested that obesity may have paradoxical survival benefits in heart ... -
Readability and Comprehensibility of Patient Information Leaflets for Antidiabetic Medications in Qatar
( SAGE Publications Inc. , 2017 , Article)Background:The readability and comprehensibility of the patient information leaflets (PILs) provided with antidiabetic medications are of questionable standards; this issue negatively affects adherence to drug therapy, ... -
The Role of Protein Tyrosine Phosphatase (PTP)-1B in Cardiovascular Disease and Its Interplay with Insulin Resistance.
( MDPI , 2019 , Article Review)Endothelial dysfunction is a key feature of cardiovascular disorders associated with obesity and diabetes. Several studies identified protein tyrosine phosphatase (PTP)-1B, a member of the PTP superfamily, as a major ... -
Synthesizing and Appraising the Quality of the Evidence on Factors Associated with Medication Adherence in Diabetes: A Systematic Review of Systematic Reviews
( Elsevier Inc. , 2017 , Article)Background Nonadherence to medications is a common phenomenon in patients with diabetes. Several studies and systematic reviews have investigated the barriers to medication adherence in diabetes. However, no study has ... -
A Systematic Review of Cost-Effectiveness of Non-Statin Lipid-Lowering Drugs for Primary and Secondary Prevention of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus
( Elsevier , 2022 , Article)Although studies of nonstatin lipid-lowering therapies have demonstrated cardiovascular benefits; whether these benefits provide good value has not been evaluated in type 2 diabetes mellitus patients. A systematic review ... -
The Impact of Clinical Pharmacist Diabetes Education on Medication Adherence in Patients with Type 2 Diabetes Mellitus: An Interventional Study from Khartoum, Sudan
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)Background: Continuous therapeutic care with good medication adherence is the cornerstone of management of all chronic diseases including diabetes. This study aimed to evaluate the impact of clinical pharmacist intervention ...