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Proliposome powders prepared using a slurry method for the generation of beclometasone dipropionate liposomes
(
Elsevier
, 2015 , Article)
A novel “slurry method” was described for the preparation of proliposome powders using soya phosphatidylcholine (SPC) with cholesterol (1:1) and for incorporation of beclometasone dipropionate (BDP) at 2mole% of the total ...
Spray-Dried Alginate Microparticles for Potential Intranasal Delivery of Ropinirole Hydrochloride: Development, Characterization and Histopathological Evaluation
(
Taylor & Francis
, 2019 , Article)
Ropinirole hydrochloride (RH) is an anti-Parkinson drug with relativity low oral bioavailability owing to its extensive hepatic first pass metabolism. Spray-dried mucoadhesive alginate microspheres of RH were developed and ...
Proliposome powder or tablets for generating inhalable liposomes using a medical nebulizer
(
Springer
, 2021 , Article)
© 2020, The Author(s). Purpose: The aim of this study was to develop and compare proliposome powder and proliposome tablet formulations for drug delivery from a Pari-LC Sprint nebulizer. Methods: Proliposome powders were ...
Delivery of anticancer molecules using carbon nanotubes
(
Springer International Publishing
, 2016 , Book chapter)
Since their discovery in 1991, carbon nanotubes (CNTs) have emerged as material structures with numerous potential applications with a number of products already in the market place. An exciting application, which is ...
Design characteristics of inhaler devices used for pulmonary delivery of medical aerosols
(
Springer International Publishing
, 2016 , Book chapter)
For the treatment of respiratory diseases, it is vital to deliver therapeutic doses of drugs to specific regions in the tracheobronchial tree (TBT) of the lung with maximal efficiency and minimal wastage of medication. ...
Introduction to nanotechnology
(
Elsevier
, 2019 , Book chapter)
Nanotechnology describes the science and technology related to the control and manipulation of matter and devices on a scale less than 100 nm and involves fields such as applied physics, materials science, chemistry, ...
Impact of nanosizing on the formation and characteristics of polymethacrylate films: micro- versus nano-suspensions
(
Taylor and Francis Ltd.
, 2021 , Article)
Aqueous-based film coating suspensions are associated with reliance on alkalinising reagents and poor film formation. The impact of particle size in this process and resultant film properties remains unclear. This study ...
Amlexanox-loaded nanoliposomes showing enhanced anti-inflammatory activity in cultured macrophages: A potential formulation for treatment of oral aphthous stomatitis
(
Elsevier
, 2023 , Article)
Oral aphthous stomatitis is a common disorder treated with the immunomodulatory drug Amlexanox (AMX), that was administered as a mucoadhesive paste (Aphthasol®). This product was discontinued by FDA in 2014 due to the ...
A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies
(
Elsevier B.V.
, 2016 , Article)
Membrane extrusion was investigated for predicting the stability of soya phosphatidylcholine liposomes and surfactosomes (Tween 80-enriched liposomes) to nebulization. Formulations were prepared with or without cholesterol, ...
Liposome mediated-CYP1A1 gene silencing nanomedicine prepared using lipid film-coated proliposomes as a potential treatment strategy of lung cancer.
(
Elsevier
, 2019 , Article)
The occurrence of lung cancer is linked with tobacco smoking, mainly through the generation of polycyclic aromatic hydrocarbons (PAHs). Elevated activity of cytochrome P4501A1 (CYP1A1) plays an important role in the metabolic ...