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Instrumentation of Flow-Through USP IV Dissolution Apparatus to Assess Poorly Soluble Basic Drug Products: a Technical Note
(
Springer New York LLC
, 2016 , Article)
Supersaturation and precipitation are common limitations encountered especially with poorly soluble basic drugs. The aims of this work were to explore the pattern of dissolution and precipitation of poorly soluble basic ...
Delivery of anticancer molecules using carbon nanotubes
(
Springer International Publishing
, 2016 , Book chapter)
Since their discovery in 1991, carbon nanotubes (CNTs) have emerged as material structures with numerous potential applications with a number of products already in the market place. An exciting application, which is ...
Design characteristics of inhaler devices used for pulmonary delivery of medical aerosols
(
Springer International Publishing
, 2016 , Book chapter)
For the treatment of respiratory diseases, it is vital to deliver therapeutic doses of drugs to specific regions in the tracheobronchial tree (TBT) of the lung with maximal efficiency and minimal wastage of medication. ...
Preparation and Characterization of Letrozole-Loaded Poly (D,L-Lactide) Nanoparticles for Breast Cancer Therapy
(
Hamad bin Khalifa University Press (HBKU Press)
, 2016 , Conference Paper)
Introduction: Breast cancer has been ranked first as the most prevalent type of cancer and the leading cause of cancer-related mortality among women worldwide. Letrozole (LTZ), an aromatase inhibitor, has been shown to be ...
A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies
(
Elsevier B.V.
, 2016 , Article)
Membrane extrusion was investigated for predicting the stability of soya phosphatidylcholine liposomes and surfactosomes (Tween 80-enriched liposomes) to nebulization. Formulations were prepared with or without cholesterol, ...