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Proliposome powder or tablets for generating inhalable liposomes using a medical nebulizer
(
Springer
, 2021 , Article)
© 2020, The Author(s). Purpose: The aim of this study was to develop and compare proliposome powder and proliposome tablet formulations for drug delivery from a Pari-LC Sprint nebulizer. Methods: Proliposome powders were ...
Impact of phospholipids, surfactants and cholesterol selection on the performance of transfersomes vesicles using medical nebulizers for pulmonary drug delivery
(
Elsevier
, 2021 , Article)
The aim of this study is to formulate and optimize novel transfersome formulations for pulmonary drug delivery. Transfersome formulations (F1 – F18) were prepared by a thin-film method using three phospholipids (Soya ...
Recent advancements in stimuli responsive drug delivery platforms for active and passive cancer targeting
(
MDPI AG
, 2021 , Article Review)
The tumor-specific targeting of chemotherapeutic agents for specific necrosis of cancer cells without affecting the normal cells poses a great challenge for researchers and scientists. Though extensive research has been ...
Fabrication, characterization and optimization of nanostructured lipid carrier formulations using Beclomethasone dipropionate for pulmonary drug delivery via medical nebulizers
(
Elsevier
, 2021 , Article)
Aerosolization is a non-invasive approach in drug delivery for localized and systemic effect. Nanostructured lipid carriers (NLCs) are new generation versatile carriers, which offer protection from degradation and enhance ...
Galactosylated iron oxide nanoparticles for enhancing oral bioavailability of ceftriaxone
(
Taylor and Francis Ltd.
, 2021 , Article)
The current study focuses on the development, characterization, biocompatibility investigation and oral bioavailability evaluation of ceftriaxone (CFT)-loaded lactobionic acid (LBA)-functionalized iron oxide magnetic ...
Impact of nanosizing on the formation and characteristics of polymethacrylate films: micro- versus nano-suspensions
(
Taylor and Francis Ltd.
, 2021 , Article)
Aqueous-based film coating suspensions are associated with reliance on alkalinising reagents and poor film formation. The impact of particle size in this process and resultant film properties remains unclear. This study ...
Piroxicam loaded polymer hybrid microspheres based tablets with modified release kinetics: Development, characterization and in vivo evaluation
(
Pakistan Journal of Pharmaceutical Sciences
, 2021 , Article)
Piroxicam (PC) is a non-steroidal anti-inflammatory drug characterized by poor aqueous solubility and
reported to cause and impart crucial GIT irritation, bleeding, peptic and duodenal ulcer. Engineering of PC ...
Cyclodextrin diethyldithiocarbamate copper ii inclusion complexes: A promising chemotherapeutic delivery system against chemoresistant triple negative breast cancer cell lines
(
MDPI AG
, 2021 , Article)
Diethyldithiocarbamate Copper II (DDC-Cu) has shown potent anticancer activity against a wide range of cancer cells, but further investigations are hindered by its practical insolubility in water. In this study, inclusion ...
Norfloxacin loaded lipid polymer hybrid nanoparticles for oral administration: Fabrication, characterization, in silico modelling and toxicity evaluation
(
MDPI
, 2021 , Article)
Norfloxacin (NOR), widely employed as an anti-bacterial drug, has poor oral bioavailability. Nano based drug delivery systems are widely used to overcome the existing oral bioavailability challenges. Lipid–Polymer Hybrid ...