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السجلات المعروضة 131 -- 140 من 916
Spray-Dried Alginate Microparticles for Potential Intranasal Delivery of Ropinirole Hydrochloride: Development, Characterization and Histopathological Evaluation
(
Taylor & Francis
, 2019 , Article)
Ropinirole hydrochloride (RH) is an anti-Parkinson drug with relativity low oral bioavailability owing to its extensive hepatic first pass metabolism. Spray-dried mucoadhesive alginate microspheres of RH were developed and ...
Prevention and screening recommendations in type 2 diabetes: Review and critical appraisal of clinical practice guidelines.
(
Elsevier
, 2018 , Article)
The aim of this review was to identify and appraise guidelines reporting recommendations for the screening and prevention of type 2 diabetes. Five guidelines were included for analysis and all were endorsed by national or ...
Medication errors in hospitals in the Middle East: a systematic review of prevalence, nature, severity and contributory factors
(
Springer
, 2019 , Article)
© 2019, The Author(s). Purpose: The aim was to critically appraise, synthesise and present the evidence of medication errors amongst hospitalised patients in Middle Eastern countries, specifically prevalence, nature, ...
Microparticles as Potential Mediators of High Glucose-Induced Renal Cell Injury.
(
MDPI
, 2019 , Article)
Diabetic nephropathy (DN) is the most common cause of chronic kidney disease worldwide. Activation of signaling pathways such as the mammalian target of rapamycin (mTOR), extracellular signal-regulated kinases (ERK), ...
Maternal and perinatal outcomes and pharmacological management of Covid-19 infection in pregnancy: a systematic review protocol
(
BMC
, 2020 , Article)
Over 4.2 million confirmed cases and more than 285,000 deaths, COVID-19 pandemic continues to harm significant number of people worldwide. Several studies have reported the impact of COVID-19 in general population; however, ...
Impact of a pharmacist-delivered discharge and follow-up intervention for patients with acute coronary syndromes in Qatar: A study protocol for a randomised controlled trial
(
BMJ Publishing Group
, 2016 , Article)
Introduction: Acute coronary syndrome (ACS) is one of the leading causes of morbidity and mortality worldwide. Secondary cardiovascular risk reduction therapy (consisting of an aspirin, a ?-blocker, an ACE inhibitor or an ...
Open-label study of absorption and clearance of 1% voriconazole eye drops
(
American Society for Microbiology
, 2016 , Article)
Twenty participants undergoing elective cataract surgery received 1% voriconazole eye drops (1 drop per eye) either 20, 40, 60, or 80 min before surgery. Median voriconazole concentrations of 1.9 to 3.2 mg/liter in aqueous ...
Development of a biocompatible creatinine-based niosomal delivery system for enhanced oral bioavailability of clarithromycin
(
Taylor and Francis Ltd
, 2016 , Article)
Context: Nonionic surfactant vesicles have gained increasing scientific attention for hydrophobic drugs delivery due to their biocompatibility, stability and low cost. Objective: The aim of the present study was to synthesize ...
Incidence of co-trimoxazole-induced hyperkalemia in a tertiary care hospital
(
Dovepress
, 2021 , Article)
Background: Co-trimoxazole is a broad-spectrum antibiotic associated with hyperkalemia. Objective: To determine the incidence of hyperkalemia and its risk factors in patients receiving co-trimoxazole. Materials and Methods: ...
Suppression of GATA-3 increases adipogenesis, reduces inflammation and improves insulin sensitivity in 3T3L-1 preadipocytes
(
Elsevier
, 2020 , Article)
© 2020 Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes. Adipose tissue inflammation is a crucial mediator of this process. GATA-3 plays important ...