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السجلات المعروضة 141 -- 150 من 920
Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
(
Elsevier
, 2021 , Article)
HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. It is characterized by aggressive behavior and treatment resistance. On the other hand, poly (amidoamine) (PAMAM) ...
Inhibition of p90 ribosomal S6 kinase potentiates cisplatin activity in A549 human lung adenocarcinoma cells
(
Wiley
, 2020 , Article)
© 2020 Royal Pharmaceutical Society Aim: Cisplatin is a standard treatment approach against lung adenocarcinoma. Resistance to cisplatin and the toxic side effects of cisplatin continue to remain a challenge. Combining ...
Sugar-based novel niosomal nanocarrier system for enhanced oral bioavailability of levofloxacin
(
Taylor and Francis Ltd
, 2016 , Article)
Context: Vesicular systems have attracted great attention in drug delivery because of their amphiphilicity, biodegradability, non-toxicity and potential for increasing drug bioavailability. Objective: A novel sugar-based ...
Proton pump inhibitor co-prescription with dual antiplatelet therapy among patients with acute coronary syndrome in Qatar
(
Springer Netherlands
, 2016 , Article)
Background There are increasing concerns about clinically significant interactions between proton pump inhibitors (PPIs) and clopidogrel, resulting in adverse cardiovascular outcomes in patients with acute coronary syndromes ...
A Facile and Novel Approach to Manufacture Paclitaxel-Loaded Proliposome Tablet Formulations of Micro or Nano Vesicles for Nebulization
(
Springer
, 2020 , Article)
© 2020, The Author(s). Purpose: The aim of this study was to develop novel paclitaxel-loaded proliposome tablet formulations for pulmonary drug delivery. Method: Proliposome powder formulations (i.e. F1 – F27) were prepared ...
Self-reported attitudes and perceived preparedness to provide pharmaceutical care among final year pharmacy students in Qatar and Kuwait
(
International Pharmaceutical Federation
, 2018 , Article)
Purpose: While pharmaceutical care (PC) had been introduced and taught in schools of pharmacy decades ago, it is still being introduced with different degrees of success in many developing countries around the world. This ...
Protein expression profiling identifies key proteins and pathways involved in growth inhibitory effects exerted by guggulsterone in human colorectal cancer cells
(
MDPI AG
, 2019 , Article)
Colorectal cancer (CRC) is a leading killer cancer worldwide and one of the most common malignancies with increasing incidences of mortality. Guggulsterone (GS) is a plant sterol used for treatment of various ailments such ...
Exploring the experiences and preparedness of humanitarian pharmacists in responding to an emergency-response situation
(
Elsevier
, 2020 , Article)
Background: Pharmacists are more frequently being deployed along with other members of the multi-disciplinary team in order to provide humanitarian aid. This team will need to work collaboratively to overcome challenges ...
Knowledge and perception about pharmacovigilance among pharmacy students of universities in Sana'a Yemen
(
Journal of Clinical and Diagnostic Research
, 2017 , Article)
Introduction: Pharmacists in community or hospital setting play a key role in reporting Adverse Drug Reaction (ADRs) during practice. Under reporting is considered as a profession malpractice worldwide. Aim: To determine ...
Characteristics and quality of adverse drug reaction reporting: a comparison of pharmacists with other healthcare providers at a multi-specialty hospital in Qatar
(
Springer International Publishing
, 2017 , Article)
Objective: Rumailah Hospital (RH) is a multi-specialty hospital with a capacity of 605 beds that serves subacute and long-term patients in Qatar. Since under-reporting and low-quality reporting of adverse drug reactions ...