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Now showing items 891-900 of 940
Clinical pharmacists’ interventions for preventing adverse events in critically ill neonates in Qatar: an economic impact analysis
(
Springer Nature
, 2024 , Article)
Objective: This study aimed to assess the overall economic impact of clinical pharmacist interventions in the neonatal ICU (NICU) in Qatar. Methods: A retrospective review of neonates’ records was performed over a 3-month ...
Pharmacoeconomic evaluation of fluconazole, posaconazole and voriconazole for antifungal prophylaxis in patients with acute myeloid leukaemia undergoing first consolidation chemotherapy
(
Oxford University Press
, 2013 , Article)
Background: Fluconazole, posaconazole and voriconazole are used prophylactically in patients with acute myeloid leukaemia (AML). This study evaluated the clinical and economic outcomes of these agents when used in AML ...
Medication use problems and factors affecting older adults in primary healthcare
(
Elsevier
, 2023 , Article)
Background: As the largest demographic group utilizing primary healthcare facilities, older adults often face the challenge of managing multiple chronic illnesses, leading to numerous medications. Objective: The present ...
Exploring determinants of antimicrobial prescribing behaviour using the Theoretical Domains Framework
(
Elsevier
, 2024 , Article)
BackgroundFew theoretically-based, qualitative studies have explored determinants of antimicrobial prescribing behaviour in hospitals. Understanding these can promote successful development and implementation of behaviour ...
Impact of pharmaceutical care interventions in improving clinical outcomes among patients with pulmonary tuberculosis: a systematic review
(
Taylor & Francis
, 2024 , Article)
Background: Pharmacists can play an important role in the fight against tuberculosis (TB) through optimising medication use and safety, promoting adherence to anti-TB drugs, and providing patient education. Limited evidence ...
Apabetalone (RVX-208): A Potential Epigenetic Therapy for the Treatment of Cardiovascular, Renal, Neurological, Viral, and Cancer Disorders
(
American Chemical Society (ACS)
, 2024 , Article)
Bromodomain and extra-terminal domain proteins (BET proteins) are epigenetic reader proteins that have been implicated in regulating gene expression through binding to chromatin and interaction with transcription factors. ...
Soft biodegradable elastomers based on poly (octanediol-tartarate) for drug delivery and tissue engineering: Synthesis, characterization and biocompatibility studies
(
Taylor & Francis
, 2011 , Article)
The synthesis, characterization and cytocompatibility of amorphous poly (octanediol-tartarate) thermoset biodegradable elastomeric polyesters are reported. The synthesis was achieved by preparing an aliphatic saturated ...
Shrinking the battlefield in cancer therapy: Nanotechnology against cancer stem cells
(
Elsevier
, 2023 , Article)
Cancer remains one of the leading causes of mortality worldwide, presenting a significant healthcare challenge owing to the limited efficacy of current treatments. The application of nanotechnology in cancer treatment ...
Optimizing polypharmacy management in the elderly: a comprehensive European benchmarking survey and the development of an innovative online benchmarking application
(
Frontiers Media
, 2023 , Article)
Background: Polypharmacy, defined as the simultaneous use of multiple medications by a patient, is a worldwide problem of rising prevalence. Paving the way for drug interactions, adverse drug reactions and non-adherence, ...
Obesity Paradox among Heart Failure with Reduced Ejection Fraction Patients: A Retrospective Cohort Study
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2022 , Article)
Background and Objectives: There is consensus on the negative effects of obesity on the development of heart failure. However, several studies have suggested that obesity may have paradoxical survival benefits in heart ...