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The role of CD44, hyaluronan and NHE1 in cardiac remodeling.
(
Elsevier
, 2018 , Article)
Cardiac remodeling, characterized by excessive extracellular matrix (ECM) remodeling, predisposes the heart to failure if left unresolved. Understanding the signaling mechanisms involved in excessive extracellular matrix ...
Heart Function and Hemodynamics Analysis for Zebrafish Embryos
(
Wiley
, 2017 , Article)
The zebrafish has emerged to become a powerful vertebrate animal model for cardiovascular research in recent years. Its advantages include easy genetic manipulation, transparency, small size, low cost, and the ability to ...
Elaeagnus angustifolia Plant Extract Inhibits Angiogenesis and Downgrades Cell Invasion of Human Oral Cancer Cells via Erk1/Erk2 Inactivation.
(
Taylor & Francis (Routledge)
, 2018 , Article)
Oral cancer is a common malignancy in both men and women worldwide; this cancer is characterized by a marked propensity for invasion and spreading to local lymph nodes. On the other hand, Elaeagnus angustifolia (EA) is a ...
Effect of flow-induced shear stress in nanomaterial uptake by cells: Focus on targeted anti-cancer therapy
(
MDPI
, 2020 , Article)
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Recently, nanomedicines have gained a great deal of attention in diverse biomedical applications, including anti-cancer therapy. Being different from normal tissue, ...
Characterization of Endothelial Cilia Distribution During Cerebral-Vascular Development in Zebrafish (Danio rerio)
(
American Heart Association
, 2018 , Article)
Objective—Endothelial cells (ECs) sense and respond to flow-induced mechanical stress, in part, via microtubule-based projections called primary cilia. However, many critical steps during vascular morphogenesis occur ...
Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening.
(
Frontiers
, 2021 , Article)
Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung condition. It is characterized by disruption of gas exchange inside the alveoli, accumulation of protein edema, and an increase in lung stiffness. ...
Effect of left atrial ligation-driven altered inflow hemodynamics on embryonic heart development: clues for prenatal progression of hypoplastic left heart syndrome.
(
Springer
, 2021 , Article)
Congenital heart defects (CHDs) are abnormalities in the heart structure present at birth. One important condition is hypoplastic left heart syndrome (HLHS) where severely underdeveloped left ventricle (LV) cannot support ...
Support of intelligent emergent materials to combat COVID-19 pandemic
(
Springer
, 2021 , Article)
The COVID-19 pandemic, associated with SARS-CoV-2 infection
transmitted via human to human and cause lifethreatening
respiratory diseases, has emerged as an everincreasing
global health and economic crisis since its ...
Dexamethasone and transdehydroandrosterone significantly reduce pulmonary epithelial cell injuries associated with mechanical ventilation.
(
American Physiological Society
, 2021 , Article)
Many patients who suffer from pulmonary diseases cannot inflate their lungs normally, as they need mechanical ventilation (MV) to assist them. The stress associated with MV can damage the delicate epithelium in small airways ...
Mechanosensitive Pathways in Heart Development: Findings from Chick Embryo Studies.
(
MDPI
, 2021 , Article)
The heart is the first organ that starts to function in a developing embryo. It continues to undergo dramatic morphological changes while pumping blood to the rest of the body. Genetic regulation of heart development is ...