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Heart Function and Hemodynamics Analysis for Zebrafish Embryos
(
Wiley
, 2017 , Article)
The zebrafish has emerged to become a powerful vertebrate animal model for cardiovascular research in recent years. Its advantages include easy genetic manipulation, transparency, small size, low cost, and the ability to ...
Effect of flow-induced shear stress in nanomaterial uptake by cells: Focus on targeted anti-cancer therapy
(
MDPI
, 2020 , Article)
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Recently, nanomedicines have gained a great deal of attention in diverse biomedical applications, including anti-cancer therapy. Being different from normal tissue, ...
Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening.
(
Frontiers
, 2021 , Article)
Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung condition. It is characterized by disruption of gas exchange inside the alveoli, accumulation of protein edema, and an increase in lung stiffness. ...
Effect of left atrial ligation-driven altered inflow hemodynamics on embryonic heart development: clues for prenatal progression of hypoplastic left heart syndrome.
(
Springer
, 2021 , Article)
Congenital heart defects (CHDs) are abnormalities in the heart structure present at birth. One important condition is hypoplastic left heart syndrome (HLHS) where severely underdeveloped left ventricle (LV) cannot support ...
Support of intelligent emergent materials to combat COVID-19 pandemic
(
Springer
, 2021 , Article)
The COVID-19 pandemic, associated with SARS-CoV-2 infection
transmitted via human to human and cause lifethreatening
respiratory diseases, has emerged as an everincreasing
global health and economic crisis since its ...
Dexamethasone and transdehydroandrosterone significantly reduce pulmonary epithelial cell injuries associated with mechanical ventilation.
(
American Physiological Society
, 2021 , Article)
Many patients who suffer from pulmonary diseases cannot inflate their lungs normally, as they need mechanical ventilation (MV) to assist them. The stress associated with MV can damage the delicate epithelium in small airways ...
Mechanosensitive Pathways in Heart Development: Findings from Chick Embryo Studies.
(
MDPI
, 2021 , Article)
The heart is the first organ that starts to function in a developing embryo. It continues to undergo dramatic morphological changes while pumping blood to the rest of the body. Genetic regulation of heart development is ...
From Acellular Matrices to Smart Polymers: Degradable Scaffolds that are Transforming the Shape of Urethral Tissue Engineering.
(
MDPI
, 2019 , Article)
Several congenital and acquired conditions may result in severe narrowing of the urethra in men, which represent an ongoing surgical challenge and a significant burden on both health and quality of life. In the field of ...
Assessment of calcified aortic valve leaflet deformations and blood flow dynamics using fluid-structure interaction modeling
(
Elsevier
, 2017 , Article)
Aortic valve diseases are among the most common cardiovascular defects. Since a non-functioning valve results in disturbed blood flow conditions, the diagnosis of such defects is based on identification of stenosis via ...
Application of a flow-induced stress wave and investigation of associated injuries on cell monolayers using a parallel plate flow chamber
(
MDPI
, 2020 , Article)
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Parallel plate flow chambers are widely used to expose cultured cells to physiological flows for the investigation of a variety of diseases. These applications ...