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Now showing items 91-98 of 98
First sliding Amyand hernia harbouring appendicular schistosomiasis: Case report
(
Elsevier Ltd
, 2019 , Article)
Introduction: Amyand's hernia (AH) is rare, schistosomiasis of the appendix is very uncommon, and both conditions coexisting together is an extremely rare event. Pre-operative diagnosis of each of the two conditions is ...
Diagnostic value of bronchoalveolar lavage in the subset of patients with negative sputum/smear and mycobacterial culture and a suspicion of pulmonary tuberculosis
(
Elsevier B.V.
, 2019 , Article)
Background: The diagnostic value of bronchoalveolar lavage in patients with negative sputum/smear for tuberculous bacilli has been well studied. However, its value in the subset of patients with both negative sputum/smear ...
Encoding the β-Arrestin Trafficking Fate of Ghrelin Receptor GHSR1a: C-Tail-Independent Molecular Determinants in GPCRs
(
American Chemical Society
, 2019 , Article)
G-protein-coupled receptors (GPCRs) can bias signaling through distinct biochemical pathways that originate from G-protein/receptor and β-arrestin/receptor complexes. Receptor conformations supporting β-arrestin engagement ...
Drug-free holidays: Compliance, tolerability, and acceptability of a 3-day atovaquone/proguanil schedule for pretravel malaria chemoprophylaxis in australian travelers
(
Oxford University Press
, 2019 , Article)
Background
Poor compliance with chemoprophylaxis is a major contributing factor to the risk of malaria in travelers. Pre-travel chemoprophylaxis may improve compliance by enabling “drug-free holidays.” The standard treatment ...
Autism spectrum disorder: A concept in evolution
(
slack journals
, 2019 , Article)
Autism is a fascinating topic that has attracted the interest of researchers and the lay public alike. The history of autism is filled with accomplishments of people who were astute observers of childhood psychopathology. ...
P-value driven methods were underpowered to detect publication bias: analysis of Cochrane review meta-analyses
(
Elsevier
, 2019 , Article)
To investigate the effect of number of studies in a meta-analysis on the detection of publication bias using p-value driven methods. The proportion of meta-analyses detected by Egger's, Harbord's, Peters', and Begg's tests ...
PD-L1 status in breast cancer: Current view and perspectives.
(
Elsevier
, 2019 , Article)
Breast cancer was traditionally not considered a particularly immunogenic tumor. However, recent developments have shown that some aggressive triple-negative breast cancers are immunogenic, exhibit a resistance to chemotherapy ...
Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity
(
Elsevier
, 2019 , Article)
The study of rare families with inherited pain insensitivity can identify new human-validated analgesic drug targets. Here, a 66-yr-old female presented with nil requirement for postoperative analgesia after a normally ...