Browsing Biomedical Research Center Research by Author "n 97923942"
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Advances in osteobiologic materials for bone substitutes.
Hasan, Anwarul; Byambaa, Batzaya; Morshed, Mahboob; Cheikh, Mohammad Ibrahim; Shakoor, Rana Abdul; Mustafy, Tanvir; Marei, Hany E... more authors ... less authors ( John Wiley and Sons , 2018 , Article Review)A significant challenge in the current orthopedics is the development of suitable osteobiologic materials that can replace the conventional allografts, autografts, and xenografts and thereby serve as implant materials as ... -
Air-jet spun tissue engineering scaffolds incorporated with diamond nanosheets with improved mechanical strength and biocompatibility
Augustine, Robin; Kalva, Sumama Nuthana; Dalvi, Yogesh B.; Varghese, Ruby; Chandran, Maneesh; Hasan, Anwarul... more authors ... less authors ( Elsevier , 2023 , Article)The development of highly porous cell supportive polymeric scaffolds with sufficient mechanical strength has always been a challenging task in tissue engineering. The widely used nanofiber fabrication methods like ... -
Cholinergic and dopaminergic neuronal differentiation of human adipose tissue derived mesenchymal stem cells.
Marei, Hany El Sayed; El-Gamal, Aya; Althani, Asma; Afifi, Nahla; Abd-Elmaksoud, Ahmed; Farag, Amany; Cenciarelli, Carlo; Thomas, Caceci; Anwarul, Hasan... more authors ... less authors ( Wiley , 2018 , Article)Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into various cell types such as cartilage, bone, and fat cells. Recent studies have shown that induction of MSCs in vitro by growth factors including ... -
Combined chemo-magnetic field-photothermal breast cancer therapy based on porous magnetite nanospheres
Sharifi, Majid; Hasan, Anwarul; Nanakali, Nadir Mustafa Qadir; Salihi, Abbas; Qadir, Fikry Ali; Muhammad, Hawzheen A.; Shekha, Mudhir Sabir; Aziz, Falah Mohammad; Amen, Karwan M.; Najafi, Farrokh; Yousefi-Manesh, Hasan; Falahati, Mojtaba... more authors ... less authors ( Nature Research , 2020 , Article)The efficacy of different modalities of treating breast cancer is inhibited by several limitations such as off-targeted drug distribution, rapid drug clearance, and drug resistance. To overcome these limitations, we developed ... -
Crosstalk between Sodium–Glucose Cotransporter Inhibitors and Sodium–Hydrogen Exchanger 1 and 3 in Cardiometabolic Diseases
Al-Shamasi, Al-Anood; Elkaffash, Rozina; Mohamed, Meram; Rayan, Menatallah; Al-Khater, Dhabya; Gadeau, Alain-Pierre; Ahmed, Rashid; Hasan, Anwarul; Eldassouki, Hussein; Yalcin, Huseyin Cagatay; Abdul-Ghani, Muhammad; Mraiche, Fatima... more authors ... less authors ( MDPI , 2021 , Article)Abnormality in glucose homeostasis due to hyperglycemia or insulin resistance is the hallmark of type 2 diabetes mellitus (T2DM). These metabolic abnormalities in T2DM lead to cellular dysfunction and the development of ... -
CTGF Loaded Electrospun Dual Porous Core-Shell Membrane For Diabetic Wound Healing
Augustine, Robin; Zahid, Alap Ali; Hasan, Anwarul; Wang, Mian; Webster, Thomas J ( Dove Medical Press Ltd. , 2019 , Article)Purpose: Impairment of wound healing is a major issue in type-2 diabetes that often causes chronic infections, eventually leading to limb and/or organ amputation. Connective tissue growth factor (CTGF) is a signaling ... -
Differentiation of human olfactory bulb-derived neural stem cells toward oligodendrocyte.
Marei, Hany E; Shouman, Zeinab; Althani, Asma; Afifi, Nahla; A, Abd-Elmaksoud; Lashen, Samah; Hasan, Anwarul; Caceci, Thomas; Rizzi, Roberto; Cenciarelli, Carlo; Casalbore, Patrizia... more authors ... less authors ( Wiley , 2018 , Article)In the central nervous system (CNS), oligodendrocytes are the glial element in charge of myelin formation. Obtaining an overall presence of oligodendrocyte precursor cells/oligodendrocytes (OPCs/OLs) in culture from different ... -
Electrospun polylactic acid/date palm polyphenol extract nanofibres for tissue engineering applications
Khadija M., Zadeh; Luyt, Adriaan S.; Zarif, Lubna; Augustine, Robin; Hasan, Anwarul; Messori, Massimo; Hassan, Mohammad K.; Yalcin, Huseyin C.... more authors ... less authors ( Springer , 2019 , Article)In this study, a set of polylactic acid (PLA)/polyphenol extracted from date palm fruit (DP) blends were prepared by electrospinning process to be used as cell culture scaffolds for tissue engineering applications. For ... -
Electrospun polyvinyl alcohol membranes incorporated with green synthesized silver nanoparticles for wound dressing applications.
Augustine, Robin; Hasan, Anwarul; Yadu Nath, V K; Thomas, Jince; Augustine, Anitha; Kalarikkal, Nandakumar; Moustafa, Ala-Eddin Al; Thomas, Sabu... more authors ... less authors ( Springer Verlag , 2018 , Article)Electrospun membranes have the potential to act as an effective barrier for wounds from the external environment to prevent pathogens. In addition, materials with good antibacterial properties can effectively fight off the ... -
Experimental investigation of volume fraction in an annulus using electrical resistance tomography
Ur Rehman, Syed Raza; Zahid, Alap Ali; Hasan, Anwarul; Hassan, Ibrahim; Rahman, M. A.; Rushd, Sayeed... more authors ... less authors ( Society of Petroleum Engineers , 2019 , Conference Paper)Horizontal drilling technology has shown to improve the production and cost-effectiveness of the well by generating multiple extraction points from a single vertical well. The efficiency of hole cleaning is reduced because ... -
Fabrication and evaluation of anti-cancer efficacy of lactoferrin-coated maghemite and magnetite nanoparticles
Sharifi, Majid; Rezayat, Seyed Mahdi; Akhtari, Keivan; Hasan, Anwarul; Falahati, Mojtaba ( Taylor and Francis Ltd. , 2019 , Article)Studies on the anti-cancer effects of nanomaterials are a very important step in the clinical practice and treatment of cancerous tissues. Since IONPs have a high potential for cancer treatment, their anti-cancer properties ... -
Fabrication and In Vitro Characterization of a Tissue Engineered PCL-PLLA Heart Valve.
Hasan, Anwarul; Soliman, Sherif; El Hajj, Fatima; Tseng, Yuan-Tsan; Yalcin, Huseyin C; Marei, Hany Elsayed... more authors ... less authors ( Nature Publishing Group , 2018 , Article)Heart valve diseases are among the leading causes of cardiac failure around the globe. Nearly 90,000 heart valve replacements occur in the USA annually. Currently, available options for heart valve replacement include ... -
Genetically unmatched human iPSC and ESC exhibit equivalent gene expression and neuronal differentiation potential.
Marei, Hany E; Althani, A; Lashen, S; Cenciarelli, C; Hasan, Anwarul ( Nature Publishing Group , 2017 , Article)The potential uniformity between differentiation and therapeutic potential of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) remains debatable. We studied the gene expression profiles, ... -
Glioma extracellular vesicles for precision medicine: prognostic and theragnostic application
Marei, Hany E.; Althani, Asmaa; Afifi, Nahla; Hasan, Anwarul; Caceci, Thomas; Cifola, Ingrid; Caratelli, Sara; Sconocchia, Giuseppe; D’Agnano, Igea; Cenciarelli, Carlo... more authors ... less authors ( Springer , 2022 , Article Review)EV produced by tumour cells carry a diverse population of proteins, lipids, DNA, and RNA molecules throughout the body and appear to play an important role in the overall development of the disease state, according to ... -
Growth factor loaded in situ photocrosslinkable poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/gelatin methacryloyl hybrid patch for diabetic wound healing
Augustine, Robin; Hasan, Anwarul; Dalvi, Yogesh B.; Rehman, Syed Raza Ur; Varghese, Ruby; Unni, Raghunath Narayanan; Yalcin, Huseyin C.; Alfkey, Rashad; Thomas, Sabu; Al Moustafa, Ala Eddin... more authors ... less authors ( Elsevier , 2021 , Article)© 2020 The Authors Management of chronic diabetic ulcers remains as a major challenge in healthcare which requires extensive multidisciplinary approaches to ensure wound protection, management of excess wound exudates and ... -
Growth factor releasing core-shell polymeric scaffolds for tissue engineering applications
Augustine, Robin; Zahid, Alap; Wang, Mian; Webster, Thomas j.; Hasan, Anwarul ( Institute of Electrical and Electronics Engineers Inc. , 2019 , Conference Paper)Tissue engineering is the use of a combination of cells, biomaterials and appropriate signals to repair or improve the functions of damaged tissues. Our group is exploiting various approaches to effectively encapsulate ... -
Inhibition of p90 ribosomal S6 kinase potentiates cisplatin activity in A549 human lung adenocarcinoma cells
Abdulrahman, Nabeel; Siveen, Kodappully Sivaraman; Joseph, Jensa Mariam; Osman, Aisha; Yalcin, Huseyin C.; Hasan, Anwarul; Uddin, Shahab; Mraiche, Fatima... more authors ... less authors ( Wiley , 2020 , Article)© 2020 Royal Pharmaceutical Society Aim: Cisplatin is a standard treatment approach against lung adenocarcinoma. Resistance to cisplatin and the toxic side effects of cisplatin continue to remain a challenge. Combining ... -
Loop-mediated isothermal amplification (Lamp): A rapid, sensitive, specific, and cost-effective point-of-care test for coronaviruses in the context of covid-19 pandemic
Augustine, Robin; Hasan, Anwarul; Das, Suvarthi; Ahmed, Rashid; Mori, Yasuyoshi; Notomi, Tsugunori; Kevadiya, Bhavesh D.; Thakor, Avnesh S.... more authors ... less authors ( MDPI , 2020 , Article)The rampant spread of COVID-19 and the worldwide prevalence of infected cases demand a rapid, simple, and cost-effective Point of Care Test (PoCT) for the accurate diagnosis of this pandemic. The most common molecular tests ... -
M cell targeting engineered biomaterials for effective vaccination
ArifulIslam, Mohammad; Firdous, Jannatul; Badruddoza, Abu Zayed Md; Reesor, Emma; Azad , Mohammad; Hasan, Anwarul; Lim, Michael; Cao, Wuji; Guillemette, Simon; SuCho, Chong... more authors ... less authors ( Elsevier Ltd , 2019 , Article)Vaccines are one of the greatest medical interventions of all time and have been successful in controlling and eliminating a myriad of diseases over the past two centuries. Among several vaccination strategies, mucosal ... -
Mesenchymal Stem Cells in the Treatment of Traumatic Brain Injury.
Hasan, Anwarul; Deeb, George; Rahal, Rahaf; Atwi, Khairallah; Mondello, Stefania; Marei, Hany Elsayed; Gali, Amr; Sleiman, Eliana; Hasan, Anwarul... more authors ... less authors ( Frontiers Media , 2017 , Article)Traumatic brain injury (TBI) is characterized by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. The ...