Browsing Biomedical Research Center Research by Title

Now showing items 492-511 of 677

    • Prevalence of antibiotic resistant Escherichia coli isolates from fecal samples of food handlers in Qatar 

      Eltai, Nahla O; Yassine, Hadi M.; Al Thani, Asmaa A.; Abu Madi, Marwan A.; Ismail, Ahmed; ... more authors ( BioMed Central , 2018 , Article)
      Background: It is well documented that food handlers harbor and shed enteric foodborne pathogens causing foodborne disease outbreaks. However, little known on enteric antibiotic resistant (AR) bacteria carriage in ...

    • Prevalence of antibiotic resistant Escherichia coli isolates from local and imported retail chicken carcasses. 

      Eltai, Nahla; Yassine, Hadi; El-Obeid, Tahra; Al-Hadidi, Sara; Al Thani, Asmaa; ... more authors ( International Association for Food Protection , 2020 , Article)
      The spread of antibiotic resistance has been associated with consumption of food contaminated with pathogenic and non-pathogenic resistant bacteria. The objective of this study was to determine the prevalence of antibiotic ...

    • Prevalence of Blastocystis sp. and other gastrointestinal pathogens among diarrheic COVID-19 patients in Italy 

      Marianna, Marangi; Boughattas, Sonia; Valzano, Felice; La Bella, Gianfranco; De Nittis, Rosella; ... more authors ( Elsevier , 2024 , Article)
      BackgroundGastrointestinal pathogens (GPs) contribute significantly to the burden of illness worldwide with diarrhoea being the most common among gastrointestinal symptoms (GSs). In the COVID-19 disease, diarrhoea, could ...

    • Prevalence of Gastrointestinal Protoz in Feral Cat Population in Qatar 

      Sharma, Aarti; Al-Sadeq, Duaa Walid; Al-Mohannadi, Maryam Saleh; Abu-Madi, Marawan Abdelhamid ( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)
      Introduction: Doha city has a high feral cat population that is estimated to outnumber its human inhabitants by 2-3:1 with a total population of 2-3 million cats according to Qatar Cat Control Unit (QCCU). Doha had a ...

    • Prevalence of hepatitis B and C viruses among migrant workers in Qatar. 

      Nasrallah, Gheyath K; Chemaitelly, Hiam; Ismail, Ahmed I A; Nizamuddin, Parveen B; Al-Sadeq, Duaa W; ... more authors ( Springer Nature , 2024 , Article)
      Limited data exist on viral hepatitis among migrant populations. This study investigated the prevalence of current hepatitis B virus (HBV) infection and lifetime hepatitis C virus (HCV) infection among Qatar's migrant craft ...

    • The prevalence of HEV among non-A-C hepatitis in Qatar and efciency of serological markers for the diagnosis of hepatitis E 

      Al Absi, Enas S.; Al-Sadeq, Duaa W.; Khalili, Makiyeh; Younes, Nadin; Al‑Dewik, Nader; ... more authors ( BMC , 2021 , Article)
      Background: The rapid growth of Qatar in the last two decades has attracted a large influx of immigrant workers who mostly come from HEV-hyperendemic countries. Thus, we aim to investigate the prevalence of HEV among acute ...

    • Prevalence of Virulence/Stress Genes in Campylobacter jejuni from Chicken Meat Sold in Qatari Retail Outlets 

      Abu-Madi, Marawan; Behnke, Jerzy M.; Sharma, Aarti; Bearden, Rebecca; Al-Banna, Nadia ( Public Library of Science , 2016 , Article)
      Chicken meat from the shelves of supermarkets in Qatar was tested for the presence of Campylobacter spp. and the presence of five virulence genes (htrB, cdtB, clpP, cadF and ciaB) was assessed in isolates. Forty eight ...

    • Production of Long-Acting CNGRC–CPG2 Fusion Proteins: New Derivatives to Overcome Drug Immunogenicity of Ligand-Directed Enzyme Prodrug Therapy for Targeted Cancer Treatment 

      Al-Mansoori, Layla; Al Qahtani, Alanod D.; Elsinga, Philip; Goda, Sayed K. ( SAGE , 2021 , Article)
      Objectives: Aminopeptidase N (APN) is an enzyme highly expressed in metastatic cancers and could be used in targeted cancer therapy. Our previous work showed the successful construction of CNGRC–carboxypeptidase G2 (CPG2) ...

    • Profiling of intestinal microbiota in patients infected with respiratory influenza a and b viruses 

      Al Khatib, Hebah A.; Mathew, Shilu; Smatti, Maria K.; Eltai, Nahla O.; Pathan, Sameer A.; ... more authors ( MDPI , 2021 , Article)
      Little is known about the association between respiratory viral infections and their impact on intestinal microbiota. Here, we compared the effect of influenza types, A and B, and influenza shedding in patients’ stools on ...

    • Profiling the Oral Microbiome and Plasma Biochemistry of Obese Hyperglycemic Subjects in Qatar 

      Sohail, Muhammad U; Elrayess, Mohamed A; Al Thani, A A; Al-Asmakh, M; Yassine, Hadi M ( MDPI , 2019 , Article)
      The present study is designed to compare demographic characteristics, plasma biochemistry, and the oral microbiome in obese (N = 37) and lean control (N = 36) subjects enrolled at Qatar Biobank, Qatar. Plasma hormones, ...

    • Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications 

      Al-Nesf, Maryam A. Y.; Abdesselem, Houari B.; Bensmail, Ilham; Ibrahim, Shahd; Saeed, Walaa A. H.; ... more authors ( Nature Research , 2022 , Article)
      COVID-19 complications still present a huge burden on healthcare systems and warrant predictive risk models to triage patients and inform early intervention. Here, we profile 893 plasma proteins from 50 severe and 50 ...

    • Protection against Reinfection with the Omicron BA.2.75 Subvariant 

      Chemaitelly, Hiam; Tang, Patrick; Coyle, Peter; Yassine, Hadi M.; Al-Khatib, Hebah A.; ... more authors ( Massachusetts Medical Society , 2023 , Other)
      The BA.2.75 sublineage of the B.1.1.529 (omicron) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may escape neutralizing antibodies. The BA.2.75 sublineage (primarily the BA.2.75.2 subvariant) ...

    • Protection against the omicron variant from previous SARS-CoV-2 infection 

      Altarawneh, Heba N.; Chemaitelly, Hiam; Hasan, Mohammad R.; Ayoub, Houssein H.; Qassim, Suelen; ... more authors ( Massachusetts Medical Society , 2022 , Other)
      Natural infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits strong protection against reinfection with the B.1.1.7 (alpha),1,2 B.1.351 (beta),1 and B.1.617.2 (delta)3 variants. However, the ...

    • Protection from previous natural infection compared with mRNA vaccination against SARS-CoV-2 infection and severe COVID-19 in Qatar: a retrospective cohort study 

      Hiam, Chemaitelly; Ayoub, Houssein H; AlMukdad, Sawsan; Coyle, Peter; Tang, Patrick; ... more authors ( Elsevier , 2022 , Article)
      BackgroundUnderstanding protection conferred by natural SARS-CoV-2 infection versus COVID-19 vaccination is important for informing vaccine mandate decisions. We compared protection conferred by natural infection versus ...

    • Protection of Omicron sub-lineage infection against reinfection with another Omicron sub-lineage 

      Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; ... more authors ( Nature Research , 2022 , Article)
      There is significant genetic distance between SARS-CoV-2 Omicron (B.1.1.529) variant BA.1 and BA.2 sub-lineages. This study investigates immune protection of infection with one sub-lineage against reinfection with the other ...

    • Protective Effect of Cyclically Pressurized Solid⁻Liquid Extraction Polyphenols from Grape Pomace on Oxidative Endothelial Cell Death. 

      Posadino, Anna Maria; Biosa, Grazia; Zayed, Hatem; Abou-Saleh, Haissam; Cossu, Annalisa; ... more authors ( MDPI , 2018 , Article)
      The aim of this work is the evaluation of a green extraction technology to exploit winery waste byproducts. Specifically, a solid⁻liquid extraction technology (Naviglio Extractor) was used to obtain polyphenolic antioxidants ...

    • Protective Effect of Previous SARS-CoV-2 Infection against Omicron BA.4 and BA.5 Subvariants. 

      Altarawneh, Heba N; Chemaitelly, Hiam; Ayoub, Houssein H; Hasan, Mohammad R; Coyle, Peter; ... more authors ( Massachusetts Medical Society , 2022 , Article)
      The BA.4 and BA.5 subvariants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 (omicron) variant have shown the capacity of escaping from neutralizing antibodies.1 These subvariants had an ...

    • Protein tyrosine phosphatase 1B inhibition improves endoplasmic reticulum stress-impaired endothelial cell angiogenic response: A critical role for cell survival 

      ABDELSALAM, SHAHENDA S.; PASHA, MAZHAR; EL-GAMAL, HEBA; HASAN, MARAM; ELRAYESS, MOHAMED A.; ... more authors ( Spandidos publications , 2021 , Article)
      Endoplasmic reticulum (ER) stress contributes to endothelial dysfunction, which is the initial step in atherogenesis. Blockade of protein tyrosine phosphatase (PTP)1B, a negative regulator of insulin receptors that is ...

    • Pseudomonas aeruginosa: arsenal of resistance mechanisms, decades of changing resistance profiles, and future antimicrobial therapies. 

      El Zowalaty, Mohamed E.; Al Thani, Asmaa A.; Webster, Thomas J.; El Zowalaty, Ahmed E.; Schweizer, Herbert P.; ... more authors ( Future Medicine , 2015 , Article)
      Antimicrobial resistance is one of the most serious public health issues facing humans since the discovery of antimicrobial agents. The frequent, prolonged, and uncontrolled use of antimicrobial agents are major factors ...

    • Pyridoxine non-responsive p.R336C mutation alters the molecular properties of cystathionine beta-synthase leading to severe homocystinuria phenotype 

      Al-Sadeq, Duaa W.; Thanassoulas, Angelos; Islam, Zeyaul; Kolatkar, Prasanna; Al-Dewik, Nader; ... more authors ( Elsevier , 2022 , Article)
      The prevalence of homocystinuria in Qatar is 1:1800, mainly due to a founder missense mutation p.R336C. • The cystathionine beta-synthase (CBS) R336C mutant was bacterially expressed, purified and its molecular properties ...