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Is it the time for Hepatitis E virus (HEV) Testing for Blood Donors in Qatar?
(
Qatar Foundation
, 2016 , Conference Paper)
HEV is the etiologic agent of acute hepatitis E. Although HEV usually causes a self-limiting infection, the disease may
develop into a chronic or fulminant form of Hepatitis. Sporadic HEV infections spread in several ...
Preparation, characterization, and in ovo vaccination of dextran-spermine nanoparticle DNA vaccine coexpressing the fusion and hemagglutinin genes against Newcastle disease
(
Dove Press
, 2016 , Article)
Plasmid DNA (pDNA)-based vaccines have emerged as effective subunit vaccines against viral and bacterial pathogens. In this study, a DNA vaccine, namely plasmid internal ribosome entry site-HN/F, was applied in ovo against ...
The Role of Cardiac Myosin Binding Protein C3 in Hypertrophic Cardiomyopathy- Progress and Novel Therapeutic Opportunities
(
Wiley
, 2016 , Article)
Hypertrophic cardiomyopathy (HCM) is a common autosomal dominant genetic cardiovascular disorder marked by genetic and phenotypic heterogeneity. Mutations in the gene encodes the cardiac myosin-binding protein C, cMYBPC3 ...
Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation
(
Nature Publishing Group
, 2016 , Article)
Activation of immune cells (but not B cells) with lectins is widely known. We used the structurally defined interaction between influenza hemagglutinin (HA) and its cell surface receptor sialic acid (SA) to identify a B ...
Impact of single-walled carbon nanotubes on the embryo: a brief review
(
Dove Press
, 2016 , Article)
Carbon nanotubes (CNTs) are considered one of the most interesting materials in the 21st century due to their unique physiochemical characteristics and applicability to various industrial products and medical applications. ...
The eutherian pseudoautosomal region
(
S. Karger AG
, 2016 , Article Review)
The pseudoautosomal region (PAR) is a unique segment of sequence homology between differentiated sex chromosomes where recombination occurs during meiosis. Molecular and functional properties of the PAR are distinctive ...
Chromosome aberrations and fertility disorders in domestic animals
(
Annual Reviews Inc.
, 2016 , Article Review)
The association between chromosomal abnormalities and reduced fertility in domestic animals is well recorded and has been studied for decades. Chromosome aberrations directly affect meiosis, gametogenesis, and the viability ...
Effect of recombinant human erythropoietin and doxorubicin in combination on the proliferation of MCF-7 and MDA-MB231 breast cancer cells
(
Spandidos Publications
, 2016 , Article)
Patients with cancer often exhibit signs of anemia as the result of the disease. Thus, cancer chemotherapies often include erythropoietin (EPO) in the regime to improve the survival rate of these patients. The aim of the ...
Effectiveness of antipseudomonal antibiotics and mechanisms of multidrug resistance in Pseudomonas aeruginosa
(
Polish Society of Microbiologists
, 2016 , Article)
Pseudomonas aeruginosa is a leading human pathogen that causes serious infections at various tissues and organs leading to life threatening health problems and possible deadly outcomes. Resistance patterns vary widely ...
DNA-based influenza vaccines as immunoprophylactic agents toward universality
(
Future Medicine Ltd.
, 2016 , Article Review)
Influenza is an illness of global public health concern. Influenza viruses have been responsible for several pandemics affecting humans. Current influenza vaccines have proved satisfactory safety; however, they have ...