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Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
(
MDPI
, 2021 , Article)
Diabetes-associated long-term hyperglycaemia leads to oxidative stress-mediated fibrosis in different tissues and organs. Endothelial-to-mesenchymal-transition (EndMT) appears to play a role in diabetes-associated fibrotic ...
Early Hepatic Gene Expression Profile of Lipid Metabolism of Mice on High Fat Diet after Treatment with Anti‐Obesity Drugs
(
FASEB
, 2020 , Conference Paper)
Obesity is a multifactorial disorder of global scale. The liver plays a vital role in fat metabolism. Disorder of hepatic fat metabolism is associated with obesity and fatty liver disease. This study aimed to detect the ...
Serum Uric Acid Level Is Positively Associated With Higher Bone Mineral Density at Multiple Skeletal Sites Among Healthy Qataris
(
Frontiers Media
, 2021 , Article)
Background: Oxidative stress has been implicated as a fundamental mechanism in the decline of bone mass. Although serum uric acid (SUA) has potent antioxidant properties, the findings of many epidemiological and experimental ...
Women's Health and Well-Being in the United Nations Sustainable Development Goals: A Narrative Review of Achievements and Gaps in the Gulf States.
(
MDPI
, 2020 , Article)
In 2014, United Nations member states proposed a set of sustainable development goals (SDGs) to help further the millennium development goals that they had proposed in New York in 2000. Of these 13 SDGs, Goal 3 (i.e., SDG ...
Computational model to analyze and characterize the functional mutations of NOD2 protein causing inflammatory disorder - Blau syndrome.
(
Elsevier
, 2020 , Article)
Blau syndrome (BS), which affects the eyes, skin, and joints, is an autosomal dominant genetic inflammatory disorder. BS is caused by mutations in the NOD2 gene. However, there are no direct treatments, and treatment with ...
Adiposity indicators as cardiometabolic risk predictors in adults from country with high burden of obesity
(
Dove Medical Press
, 2020 , Article)
Background : In Qatar more than 70% 0f the adults are overweight and obese. Different adiposity assessment methods have been proposed to identify individuals at cardio-metabolic risk.
Purpose : This study aimed to compare ...
Thymoquinone Suppresses Cell Proliferation and Enhances Apoptosis of HL60 Leukemia Cells through Re-Expression of JAK/STAT Negative Regulators.
(
West Asia Organization for Cancer Prevention (WAOCP)
, 2021 , Article)
The natural compound, thymoquinone (TQ) has demonstrated potential anticancer properties in inhibiting cell proliferation and promoting apoptosis in myeloid leukemia cells, breast cancer cells, and others. However, the ...
Developing an indicator system for a healthy City: Taking an urban area as a pilot
(
Dove Medical Press
, 2020 , Article)
Purpose: The Healthy Cities Project is an important strategy for global health. This study aimed to develop a scientific and appropriate indicator system for the evaluation of a Healthy City in Chongqing, China. Methods: ...
Epidemiological, molecular, and clinical features of rotavirus infections among pediatrics in Qatar
(
Springer
, 2021 , Article)
Acute gastroenteritis (AGE) remains a major cause of diarrhea in developing and developed countries. Rotavirus (RV) is a leading cause of severe pediatric diarrhea worldwide. Here we report on the prevalence of circulating ...
Dietary Supplements: Are Current Policies Adequate for Promoting Health?
(
MDPI
, 2020 , Article)
Globally, there has been a dramatic increase in the use of dietary supplements over recent decades [...].